Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia

por Stuani, Lucille, Sabatier, Marie, Sarry, Jean-Emmanuel
Publicado 2019

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

por Lopez‐Reyes, Rosa G., Quinet, Grégoire, Gonzalez‐Santamarta, Maria, Larrue, Clément, Sarry, Jean‐Emmanuel, Rodriguez, Manuel S.
Publicado 2020

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia

por Larrue, Clément, Heydt, Quentin, Saland, Estelle, Boutzen, Héléna, Kaoma, Tony, Sarry, Jean-Emmanuel, Joffre, Carine, Récher, Christian
Publicado 2019

Clinically Relevant Oxygraphic Assay to Assess Mitochondrial Energy Metabolism in Acute Myeloid Leukemia Patients

por Fovez, Quentin, Laine, William, Goursaud, Laure, Berthon, Celine, Germain, Nicolas, Degand, Claire, Sarry, Jean-Emmanuel, Quesnel, Bruno, Marchetti, Philippe, Kluza, Jerome
Publicado 2021

Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia

por Larrue, Clement, Mouche, Sarah, Lin, Shan, Simonetta, Federico, Scheidegger, Nastassja K., Poulain, Laury, Birsen, Rudy, Sarry, Jean-Emmanuel, Stegmaier, Kimberly, Tamburini, Jerome
Publicado 2023

SHED-Dependent Oncogenic Signaling of the PEAK3 Pseudo-Kinase

por Ounoughene, Youcef, Fourgous, Elise, Boublik, Yvan, Saland, Estelle, Guiraud, Nathan, Recher, Christian, Urbach, Serge, Fort, Philippe, Sarry, Jean-Emmanuel, Fesquet, Didier, Roche, Serge
Publicado 2021

Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

por Cartel, Maëlle, Mouchel, Pierre-Luc, Gotanègre, Mathilde, David, Laure, Bertoli, Sarah, Mansat-De Mas, Véronique, Besson, Arnaud, Sarry, Jean-Emmanuel, Manenti, Stéphane, Didier, Christine
Publicado 2020

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

por Mouchel, Pierre-Luc, Serhan, Nizar, Betous, Rémy, Farge, Thomas, Saland, Estelle, De Medina, Philippe, Hoffmann, Jean-Sébastien, Sarry, Jean-Emmanuel, Poirot, Marc, Silvente-Poirot, Sandrine, Récher, Christian
Publicado 2020

Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells

por Luna-Yolba, Raquel, Marmoiton, Justine, Gigo, Véronique, Marechal, Xavier, Boet, Emeline, Sahal, Ambrine, Alet, Nathalie, Abramovich, Ifat, Gottlieb, Eyal, Visentin, Virgile, Paillasse, Michael R., Sarry, Jean-Emmanuel
Publicado 2021

Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response

por Sesen, Julie, Dahan, Perrine, Scotland, Sarah J., Saland, Estelle, Dang, Van-Thi, Lemarié, Anthony, Tyler, Betty M., Brem, Henry, Toulas, Christine, Cohen-Jonathan Moyal, Elizabeth, Sarry, Jean-Emmanuel, Skuli, Nicolas
Publicado 2015

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

por Stuani, Lucille, Riols, Fabien, Millard, Pierre, Sabatier, Marie, Batut, Aurélie, Saland, Estelle, Viars, Fanny, Tonini, Laure, Zaghdoudi, Sonia, Linares, Laetitia K., Portais, Jean-Charles, Sarry, Jean-Emmanuel, Bertrand-Michel, Justine
Publicado 2018

Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation

por Boutin, Laetitia, Arnautou, Pierre, Trignol, Aurélie, Ségot, Amandine, Farge, Thomas, Desterke, Christophe, Soave, Sabrina, Clay, Denis, Raffoux, Emmanuel, Sarry, Jean-Emmanuel, Malfuson, Jean-Valère, Lataillade, Jean-Jacques, Le Bousse-Kerdilès, Marie-Caroline, Anginot, Adrienne
Publicado 2020

Coordinating Effect of VEGFC and Oleic Acid Participates to Tumor Lymphangiogenesis

por Morfoisse, Florent, De Toni, Fabienne, Nigri, Jeremy, Hosseini, Mohsen, Zamora, Audrey, Tatin, Florence, Pujol, Françoise, Sarry, Jean-Emmanuel, Langin, Dominique, Lacazette, Eric, Prats, Anne-Catherine, Tomasini, Richard, Galitzky, Jean, Bouloumié, Anne, Garmy-Susini, Barbara
Publicado 2021

APR-246 induces early cell death by ferroptosis in acute myeloid leukemia

por Birsen, Rudy, Larrue, Clement, Decroocq, Justine, Johnson, Natacha, Guiraud, Nathan, Gotanegre, Mathilde, Cantero-Aguilar, Lilia, Grignano, Eric, Huynh, Tony, Fontenay, Michaela, Kosmider, Olivier, Mayeux, Patrick, Chapuis, Nicolas, Sarry, Jean Emmanuel, Tamburini, Jerome, Bouscary, Didier
Publicado 2021

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias

por Paolillo, Rosa, Boulanger, Mathias, Gâtel, Pierre, Gabellier, Ludovic, De Toledo, Marion, Tempé, Denis, Hallal, Rawan, Akl, Dana, Moreaux, Jérôme, Baik, Hayeon, Gueret, Elise, Recher, Christian, Sarry, Jean-Emmanuel, Cartron, Guillaume, Piechaczyk, Marc, Bossis, Guillaume
Publicado 2022

Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo

por Serhan, Nizar, Mouchel, Pierre-Luc, de Medina, Philippe, Segala, Gregory, Mougel, Aurélie, Saland, Estelle, Rives, Arnaud, Lamaziere, Antonin, Despres, Gaëtan, Sarry, Jean-Emmanuel, Larrue, Clément, Vergez, François, Largeaud, Laetitia, Record, Michel, Récher, Christian, Silvente-Poirot, Sandrine, Poirot, Marc
Publicado 2020

Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold

por Griessinger, Emmanuel, Pereira-Martins, Diego, Nebout, Marielle, Bosc, Claudie, Saland, Estelle, Boet, Emiline, Sahal, Ambrine, Chiche, Johanna, Debayle, Delphine, Fleuriot, Lucile, Pruis, Maurien, De Mas, Véronique, Vergez, François, Récher, Christian, Huls, Gerwin, Sarry, Jean-Emmanuel, Schuringa, Jan Jacob, Peyron, Jean-François
Publicado 2023

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience

por LaRochelle, Olivier, Bertoli, Sarah, Vergez, François, Sarry, Jean-Emmanuel, Mansat-De Mas, Véronique, Dobbelstein, Sophie, Dastugue, Nicole, Strzelecki, Anne-Claire, Cavelier, Cindy, Creancier, Laurent, Pillon, Arnaud, Kruczynski, Anna, Demur, Cécile, Sarry, Audrey, Huguet, Françoise, Huynh, Anne, Récher, Christian, Delabesse, Eric
Publicado 2011

Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2(V617F) myeloproliferative neoplasms

por Courdy, Charly, Platteeuw, Loïc, Ducau, Charlotte, De Araujo, Isabelle, Boet, Emeline, Sahal, Ambrine, Saland, Estelle, Edmond, Valérie, Tavitian, Suzanne, Bertoli, Sarah, Cougoul, Pierre, Granat, Fanny, Poillet, Laura, Marty, Caroline, Plo, Isabelle, Sarry, Jean-Emmanuel, Manenti, Stéphane, Mansat-De Mas, Véronique, Joffre, Carine
Publicado 2023

Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions

por Seiler, Kristina, Humbert, Magali, Minder, Petra, Mashimo, Iris, Schläfli, Anna M., Krauer, Deborah, Federzoni, Elena A., Vu, Bich, Moresco, James J., Yates, John R., Sadowski, Martin C., Radpour, Ramin, Kaufmann, Thomas, Sarry, Jean-Emmanuel, Dengjel, Joern, Tschan, Mario P., Torbett, Bruce E.
Publicado 2022