Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules

por Fujimura, Ken, Sasaki, Atsuo T., Anderson, Paul
Publicado 2012

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

por Sasaki, Atsuo T., Chun, Cheryl, Takeda, Kosuke, Firtel, Richard A.
Publicado 2004

Metabolic Compartmentalization at the Leading Edge of Metastatic Cancer Cells

por Wolfe, Kara, Kamata, Ryo, Coutinho, Kester, Inoue, Takanari, Sasaki, Atsuo T.
Publicado 2020

Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ

por Takeuchi, Koh, Senda, Miki, Ikeda, Yoshiki, Okuwaki, Koji, Fukuzawa, Kaori, Nakagawa, So, Sasaki, Mika, Sasaki, Atsuo T., Senda, Toshiya
Publicado 2023

The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis

por Subramani, Arasukumar, Alsidawi, Samer, Jagannathan, Sajjeev, Sumita, Kazutaka, Sasaki, Atsuo T., Aronow, Bruce, Warnick, Ronald E., Lawler, Sean, Driscoll, James J.
Publicado 2013

G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

por Sasaki, Atsuo T., Janetopoulos, Chris, Lee, Susan, Charest, Pascale G., Takeda, Kosuke, Sundheimer, Lauren W., Meili, Ruedi, Devreotes, Peter N., Firtel, Richard A.
Publicado 2007

Anti-Tumor Potential of IMP Dehydrogenase Inhibitors: A Century-Long Story

por Naffouje, Rand, Grover, Punita, Yu, Hongyang, Sendilnathan, Arun, Wolfe, Kara, Majd, Nazanin, Smith, Eric P., Takeuchi, Koh, Senda, Toshiya, Kofuji, Satoshi, Sasaki, Atsuo T.
Publicado 2019

Site–Specific Monoubiquitination Activates Ras by Impeding GTPase Activating Protein Function

por Baker, Rachael, Lewis, Steven M., Sasaki, Atsuo T., Wilkerson, Emily M., Locasale, Jason W., Cantley, Lewis C., Kuhlman, Brian, Dohlman, Henrik G., Campbell, Sharon L.
Publicado 2012

Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification

por Osaka, Natsuki, Hirota, Yoshihisa, Ito, Doshun, Ikeda, Yoshiki, Kamata, Ryo, Fujii, Yuki, Chirasani, Venkat R., Campbell, Sharon L., Takeuchi, Koh, Senda, Toshiya, Sasaki, Atsuo T.
Publicado 2021

Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc(GTP&ATP) assay

por Kopra, Kari, Mahran, Randa, Yli-Hollo, Titta, Tabata, Sho, Vuorinen, Emmiliisa, Fujii, Yuki, Vuorinen, Iida, Ogawa-Iio, Aki, Hirayama, Akiyoshi, Soga, Tomoyoshi, Sasaki, Atsuo T., Härmä, Harri
Publicado 2023

A Homogeneous, High-Throughput Assay for Phosphatidylinositol 5-Phosphate 4-Kinase with a Novel, Rapid Substrate Preparation

por Davis, Mindy I., Sasaki, Atsuo T., Shen, Min, Emerling, Brooke M., Thorne, Natasha, Michael, Sam, Pragani, Rajan, Boxer, Matthew, Sumita, Kazutaka, Takeuchi, Koh, Auld, Douglas S., Li, Zhuyin, Cantley, Lewis C., Simeonov, Anton
Publicado 2013

Reuse of Molecules for Glioblastoma Therapy

por Koehler, Abigail, Karve, Aniruddha, Desai, Pankaj, Arbiser, Jack, Plas, David R., Qi, Xiaoyang, Read, Renee D., Sasaki, Atsuo T., Gawali, Vaibhavkumar S., Toukam, Donatien K., Bhattacharya, Debanjan, Kallay, Laura, Pomeranz Krummel, Daniel A., Sengupta, Soma
Publicado 2021

TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers

por Nakasuka, Fumie, Tabata, Sho, Sakamoto, Takeharu, Hirayama, Akiyoshi, Ebi, Hiromichi, Yamada, Tadaaki, Umetsu, Ko, Ohishi, Maki, Ueno, Ayano, Goto, Hisatsugu, Sugimoto, Masahiro, Nishioka, Yasuhiko, Yamada, Yasuhiro, Tomita, Masaru, Sasaki, Atsuo T., Yano, Seiji, Soga, Tomoyoshi
Publicado 2021

Identification of lysine methylation in the core GTPase domain by GoMADScan

por Yoshino, Hirofumi, Yin, Guowei, Kawaguchi, Risa, Popov, Konstantin I., Temple, Brenda, Sasaki, Mika, Kofuji, Satoshi, Wolfe, Kara, Kofuji, Kaori, Okumura, Koichi, Randhawa, Jaskirat, Malhotra, Akshiv, Majd, Nazanin, Ikeda, Yoshiki, Shimada, Hiroko, Kahoud, Emily Rose, Haviv, Sasson, Iwase, Shigeki, Asara, John M., Campbell, Sharon L., Sasaki, Atsuo T.
Publicado 2019

Correction: Identification of lysine methylation in the core GTPase domain by GoMADScan

por Yoshino, Hirofumi, Yin, Guowei, Kawaguchi, Risa, Popov, Konstantin I., Temple, Brenda, Sasaki, Mika, Kofuji, Satoshi, Wolfe, Kara, Kofuji, Kaori, Okumura, Koichi, Randhawa, Jaskirat, Malhotra, Akshiv, Majd, Nazanin, Ikeda, Yoshiki, Shimada, Hiroko, Kahoud, Emily Rose, Haviv, Sasson, Iwase, Shigeki, Asara, John M., Campbell, Sharon L., Sasaki, Atsuo T.
Publicado 2019

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

por Liu, Xiaoxiao, Sato, Naru, Yabushita, Tomohiro, Li, Jingmei, Jia, Yuhan, Tamura, Moe, Asada, Shuhei, Fujino, Takeshi, Fukushima, Tsuyoshi, Yonezawa, Taishi, Tanaka, Yosuke, Fukuyama, Tomofusa, Tsuchiya, Akiho, Shikata, Shiori, Iwamura, Hiroyuki, Kinouchi, Chieko, Komatsu, Kensuke, Yamasaki, Satoshi, Shibata, Tatsuhiro, Sasaki, Atsuo T, Schibler, Janet, Wunderlich, Mark, O'Brien, Eric, Mizukawa, Benjamin, Mulloy, James C, Sugiura, Yuki, Takizawa, Hitoshi, Shibata, Takuma, Miyake, Kensuke, Kitamura, Toshio, Goyama, Susumu
Publicado 2022

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

por Kofuji, Satoshi, Hirayama, Akiyoshi, Eberhardt, Alexander Otto, Kawaguchi, Risa, Sugiura, Yuki, Sampetrean, Oltea, Ikeda, Yoshiki, Warren, Mikako, Sakamoto, Naoya, Kitahara, Shuji, Yoshino, Hirofumi, Yamashita, Daisuke, Sumita, Kazutaka, Wolfe, Kara, Lange, Lisa, Ikeda, Satsuki, Shimada, Hiroko, Minami, Noriaki, Malhotra, Akshiv, Morioka, Shin, Ban, Yuki, Asano, Maya, Flanary, Victoria L, Ramkissoon, Annmarie, Chow, Lionel M.L., Kiyokawa, Juri, Mashimo, Tomoyuki, Lucey, Greg, Mareninov, Sergey, Ozawa, Tatsuya, Onishi, Nobuyuki, Okumura, Koichi, Terakawa, Jumpei, Daikoku, Takiko, Wise-Draper, Trisha, Majd, Nazanin, Kofuji, Kaori, Sasaki, Mika, Mori, Masaru, Kanemura, Yonehiro, Smith, Eric P., Anastasiou, Dimitrios, Wakimoto, Hiroaki, Holland, Eric C., Yong, William H., Horbinski, Craig, Nakano, Ichiro, DeBerardinis, Ralph J., Bachoo, Robert M., Mischel, Paul S., Yasui, Wataru, Suematsu, Makoto, Saya, Hideyuki, Soga, Tomoyoshi, Grummt, Ingrid, Bierhoff, Holger, Sasaki, Atsuo T.
Publicado 2019