Clinical efficacy and safety of topiroxostat in Japanese hyperuricemic patients with or without gout: a randomized, double-blinded, controlled phase 2b study

por Hosoya, Tatsuo, Sasaki, Tomomitsu, Ohashi, Tetsuo
Publicado 2016

The effect for hyperuricemia inpatient of uric acid overproduction type or in combination with topiroxostat on the pharmacokinetics, pharmacodynamics and safety of dotinurad, a sel...

por Okui, Daisuke, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Publicado 2019

Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: randomized, multicenter, double-...

por Hosoya, Tatsuo, Sano, Takafumi, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Publicado 2019

Dotinurad versus benzbromarone in Japanese hyperuricemic patient with or without gout: a randomized, double-blind, parallel-group, phase 3 study

por Hosoya, Tatsuo, Sano, Takafumi, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Publicado 2020

Clinical pharmacological study of dotinurad administered to male and female elderly or young subjects

por Nakatani, Hiroshi, Fushimi, Masahiko, Sasaki, Tomomitsu, Okui, Daisuke, Ohashi, Tetsuo
Publicado 2019

Open-label study of long-term administration of dotinurad in Japanese hyperuricemic patients with or without gout

por Hosoya, Tatsuo, Fushimi, Masahiko, Okui, Daisuke, Sasaki, Tomomitsu, Ohashi, Tetsuo
Publicado 2019

Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, mult...

por Hosoya, Tatsuo, Sano, Takafumi, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo
Publicado 2019

Effects of mild and moderate renal dysfunction on pharmacokinetics, pharmacodynamics, and safety of dotinurad: a novel selective urate reabsorption inhibitor

por Fukase, Hiroyuki, Okui, Daisuke, Sasaki, Tomomitsu, Fushimi, Masahiko, Ohashi, Tetsuo, Hosoya, Tatsuo
Publicado 2019