Methods to Make Homogenous Antibody Drug Conjugates

por Kline, Toni, Steiner, Alexander R., Penta, Kalyani, Sato, Aaron K., Hallam, Trevor J., Yin, Gang
Publicado 2014

A simplified and robust protocol for immunoglobulin expression in E scherichia coli cell‐free protein synthesis systems

por Cai, Qi, Hanson, Jeffrey A., Steiner, Alexander R., Tran, Cuong, Masikat, Mary Rose, Chen, Rishard, Zawada, James F., Sato, Aaron K., Hallam, Trevor J., Yin, Gang
Publicado 2015

Rapid exploration of the epitope coverage produced by an Ebola survivor to guide the discovery of therapeutic antibody cocktails

por Yuan, Tom Z, Lujan Hernandez, Ana G, Keane, Erica, Liu, Qiang, Axelrod, Fumiko, Kailasan, Shweta, Noonan-Shueh, Madeleine, Aman, Mohammad Javad, Sato, Aaron K, Abdiche, Yasmina N
Publicado 2020

Production of bispecific antibodies in “knobs-into-holes” using a cell-free expression system

por Xu, Yiren, Lee, John, Tran, Cuong, Heibeck, Tyler H, Wang, Willie D, Yang, Junhao, Stafford, Ryan L, Steiner, Alexander R, Sato, Aaron K, Hallam, Trevor J, Yin, Gang
Publicado 2014

Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission

por Kapoor, Neeraj, Vanjak, Ivana, Rozzelle, James, Berges, Aym, Chan, Wei, Yin, Gang, Tran, Cuong, Sato, Aaron K., Steiner, Alexander R., Pham, Thao P., Birkett, Ashley J., Long, Carole A., Fairman, Jeff, Miura, Kazutoyo
Publicado 2018

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

por Froude, Jeffrey W., Herbert, Andrew S., Pelat, Thibaut, Miethe, Sebastian, Zak, Samantha E., Brannan, Jennifer M., Bakken, Russell R., Steiner, Alexander R., Yin, Gang, Hallam, Trevor J., Sato, Aaron K., Hust, Michael, Thullier, Philippe, Dye, John M.
Publicado 2018

Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism

por Peterson, Sean M., Juliana, Christine A., Hu, Cameron F., Chai, Jinghua, Holliday, Carson, Chan, Kara Y., Lujan Hernandez, Ana G., Challocombe, Zoe, Wang, Linya, Han, Zhen, Haas, Nikhil, Stafford, Ryan, Axelrod, Fumiko, Yuan, Tom Z., De León, Diva D., Sato, Aaron K.
Publicado 2023

In vitro Fab display: a cell-free system for IgG discovery

por Stafford, Ryan L., Matsumoto, Marissa L., Yin, Gang, Cai, Qi, Fung, Juan Jose, Stephenson, Heather, Gill, Avinash, You, Monica, Lin, Shwu-Hwa, Wang, Willie D., Masikat, Mary Rose, Li, Xiaofan, Penta, Kalyani, Steiner, Alex R., Baliga, Ramesh, Murray, Christopher J., Thanos, Christopher D., Hallam, Trevor J., Sato, Aaron K.
Publicado 2014

Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

por Li, Xiaofan, Zhou, Sihong, Abrahams, Cristina L., Krimm, Stellanie, Smith, Jennifer, Bajjuri, Krishna, Stephenson, Heather T., Henningsen, Robert, Hanson, Jeffrey, Heibeck, Tyler H., Calarese, Daniel, Tran, Cuong, Yin, Gang, Stafford, Ryan L., Yam, Alice Y., Kline, Toni, De Almeida, Venita I., Sato, Aaron K., Lupher, Mark, Bedard, Kristin, Hallam, Trevor J.
Publicado 2023

RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

por Yin, Gang, Stephenson, Heather T., Yang, Junhao, Li, Xiaofan, Armstrong, Stephanie M., Heibeck, Tyler H., Tran, Cuong, Masikat, Mary Rose, Zhou, Sihong, Stafford, Ryan L., Yam, Alice Y., Lee, John, Steiner, Alexander R., Gill, Avinash, Penta, Kalyani, Pollitt, Sonia, Baliga, Ramesh, Murray, Christopher J., Thanos, Christopher D., McEvoy, Leslie M., Sato, Aaron K., Hallam, Trevor J.
Publicado 2017

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries

por Yuan, Tom Z., Garg, Pankaj, Wang, Linya, Willis, Jordan R., Kwan, Eric, Hernandez, Ana G Lujan, Tuscano, Emily, Sever, Emily N., Keane, Erica, Soto, Cinque, Mucker, Eric M., Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Kailasan, Shweta, Aman, M. Javad, Li, Haoyang, Hooper, Jay W., Saphire, Erica Ollmann, Crowe, James E., Liu, Qiang, Axelrod, Fumiko, Sato, Aaron K.
Publicado 2021

Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium

por Callaway, Heather M., Hastie, Kathryn M., Schendel, Sharon L., Li, Haoyang, Yu, Xiaoying, Shek, Jeremy, Buck, Tierra, Hui, Sean, Bedinger, Dan, Troup, Camille, Dennison, S. Moses, Li, Kan, Alpert, Michael D., Bailey, Charles C., Benzeno, Sharon, Bonnevier, Jody L., Chen, Jin-Qiu, Chen, Charm, Cho, Hyeseon, Crompton, Peter D., Dussupt, Vincent, Entzminger, Kevin C., Ezzyat, Yassine, Fleming, Jonathan K., Geukens, Nick, Gilbert, Amy E., Guan, Yongjun, Han, Xiaojian, Harvey, Christopher J., Hatler, Julia M., Howie, Bryan, Hu, Chao, Huang, Ailong, Imbrechts, Maya, Jin, Aishun, Kamachi, Nik, Keitany, Gladys, Klinger, Mark, Kolls, Jay K., Krebs, Shelly J., Li, Tingting, Luo, Feiyan, Maruyama, Toshiaki, Meehl, Michael A., Mendez-Rivera, Letzibeth, Musa, Andrea, Okumura, C.J., Rubin, Benjamin E.R., Sato, Aaron K., Shen, Meiying, Singh, Anirudh, Song, Shuyi, Tan, Joshua, Trimarchi, Jeffrey M., Upadhyay, Dhruvkumar P., Wang, Yingming, Yu, Lei, Yuan, Tom Z., Yusko, Erik, Peters, Bjoern, Tomaras, Georgia, Saphire, Erica Ollmann
Publicado 2023