ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGFβ pathway genes through histone deacetylation

por Saika, Makoto, Inoue, Daichi, Nagase, Reina, Sato, Naru, Tsuchiya, Akiho, Yabushita, Tomohiro, Kitamura, Toshio, Goyama, Susumu
Publicado 2018

P407: MITOTIC FIDELITY IS A RESISTANCE MECHANISM TO DECITABINE IN MYELOID TUMORS.

por Yabushita, Tomohiro, Chinen, Takumi, Nishiyama, Atsuya, Asada, Shuhei, Yamamoto, Keita, Sato, Naru, Enomoto, Yutaka, Katoh, Keiko, Saitoh, Kaori, Ishikawa, Takamasa, Soga, Tomoyoshi, Nannya, Yasuhito, Nakanishi, Makoto, Kitagawa, Daiju, Kitamura, Toshio, Goyama, Susumu
Publicado 2023

CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression

por Liu, Xiaoxiao, Sato, Naru, Shimosato, Yuko, Wang, Teh‐Wei, Denda, Tamami, Chang, Yu‐Hsuan, Yabushita, Tomohiro, Fujino, Takeshi, Asada, Shuhei, Tanaka, Yosuke, Fukuyama, Tomofusa, Enomoto, Yutaka, Ota, Yasunori, Sakamoto, Takeharu, Kitamura, Toshio, Goyama, Susumu
Publicado 2022

Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway

por Fujino, Takeshi, Goyama, Susumu, Sugiura, Yuki, Inoue, Daichi, Asada, Shuhei, Yamasaki, Satoshi, Matsumoto, Akiko, Yamaguchi, Kiyoshi, Isobe, Yumiko, Tsuchiya, Akiho, Shikata, Shiori, Sato, Naru, Morinaga, Hironobu, Fukuyama, Tomofusa, Tanaka, Yosuke, Fukushima, Tsuyoshi, Takeda, Reina, Yamamoto, Keita, Honda, Hiroaki, Nishimura, Emi K., Furukawa, Yoichi, Shibata, Tatsuhiro, Abdel-Wahab, Omar, Suematsu, Makoto, Kitamura, Toshio
Publicado 2021

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

por Liu, Xiaoxiao, Sato, Naru, Yabushita, Tomohiro, Li, Jingmei, Jia, Yuhan, Tamura, Moe, Asada, Shuhei, Fujino, Takeshi, Fukushima, Tsuyoshi, Yonezawa, Taishi, Tanaka, Yosuke, Fukuyama, Tomofusa, Tsuchiya, Akiho, Shikata, Shiori, Iwamura, Hiroyuki, Kinouchi, Chieko, Komatsu, Kensuke, Yamasaki, Satoshi, Shibata, Tatsuhiro, Sasaki, Atsuo T, Schibler, Janet, Wunderlich, Mark, O'Brien, Eric, Mizukawa, Benjamin, Mulloy, James C, Sugiura, Yuki, Takizawa, Hitoshi, Shibata, Takuma, Miyake, Kensuke, Kitamura, Toshio, Goyama, Susumu
Publicado 2022