Systematic approaches to identify E3 ligase substrates

por Iconomou, Mary, Saunders, Darren N.
Publicado 2016

Cancer in the news: Bias and quality in media reporting of cancer research

por Amberg, Amanda, Saunders, Darren N.
Publicado 2020

Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity

por Stillfried, Gillian E, Saunders, Darren N, Ranson, Marie
Publicado 2007

N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

por Belfiore, Lisa, Saunders, Darren N., Ranson, Marie, Vine, Kara L.
Publicado 2020

A Novel SERPINA1 Mutation Causing Serum Alpha(1)-Antitrypsin Deficiency

por Saunders, Darren N., Tindall, Elizabeth A., Shearer, Robert F., Roberson, Jacquelyn, Decker, Amy, Wilson, Jean Amos, Hayes, Vanessa M.
Publicado 2012

Improving the Delivery of SOD1 Antisense Oligonucleotides to Motor Neurons Using Calcium Phosphate-Lipid Nanoparticles

por Chen, Liyu, Watson, Clare, Morsch, Marco, Cole, Nicholas J., Chung, Roger S., Saunders, Darren N., Yerbury, Justin J., Vine, Kara L.
Publicado 2017

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

por Farrawell, Natalie E., Lambert-Smith, Isabella A., Warraich, Sadaf T., Blair, Ian P., Saunders, Darren N., Hatters, Danny M., Yerbury, Justin J.
Publicado 2015

Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate‐induced apoptosis

por Balaban, Seher, Lee, Lisa S., Varney, Bianca, Aishah, Atqiya, Gao, Quanqing, Shearer, Robert F., Saunders, Darren N., Grewal, Thomas, Hoy, Andrew J.
Publicado 2018

The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia

por Shearer, Robert F., Frikstad, Kari-Anne Myrum, McKenna, Jessie, McCloy, Rachael A., Deng, Niantao, Burgess, Andrew, Stokke, Trond, Patzke, Sebastian, Saunders, Darren N.
Publicado 2018

Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

por Farrawell, Natalie E., McAlary, Luke, Lum, Jeremy S., Chisholm, Christen G., Warraich, Sadaf T., Blair, Ian P., Vine, Kara L., Saunders, Darren N., Yerbury, Justin J.
Publicado 2020

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

por Lee, Jodi A., Yerbury, Justin J., Farrawell, Natalie, Shearer, Robert F., Constantinescu, Patrick, Hatters, Danny M., Schroder, Wayne A., Suhrbier, Andreas, Wilson, Mark R., Saunders, Darren N., Ranson, Marie
Publicado 2015

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

por Nagarajan, Shilpa R., Brandon, Amanda E., McKenna, Jessie A., Shtein, Harrison C., Nguyen, Thinh Q., Suryana, Eurwin, Poronnik, Philip, Cooney, Gregory J., Saunders, Darren N., Hoy, Andrew J.
Publicado 2017

Correction: Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver

por Nagarajan, Shilpa R., Brandon, Amanda E., McKenna, Jessie A., Shtein, Harrison C., Nguyen, Thinh Q., Suryana, Eurwin, Poronnik, Philip, Cooney, Gregory J., Saunders, Darren N., Hoy, Andrew J.
Publicado 2017

ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

por Farrawell, Natalie E, Bax, Monique, McAlary, Luke, McKenna, Jessie, Maksour, Simon, Do-Ha, Dzung, Rayner, Stephanie L, Blair, Ian P, Chung, Roger S, Yerbury, Justin J, Ooi, Lezanne, Saunders, Darren N
Publicado 2023

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

por Balaban, Seher, Shearer, Robert F., Lee, Lisa S., van Geldermalsen, Michelle, Schreuder, Mark, Shtein, Harrison C., Cairns, Rose, Thomas, Kristen C., Fazakerley, Daniel J., Grewal, Thomas, Holst, Jeff, Saunders, Darren N., Hoy, Andrew J.
Publicado 2017

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

por Bax, Monique, McKenna, Jessie, Do-Ha, Dzung, Stevens, Claire H., Higginbottom, Sarah, Balez, Rachelle, Cabral-da-Silva, Mauricio e Castro, Farrawell, Natalie E., Engel, Martin, Poronnik, Philip, Yerbury, Justin J., Saunders, Darren N., Ooi, Lezanne
Publicado 2019

Mitochondrial mutations and metabolic adaptation in pancreatic cancer

por Hardie, Rae-Anne, van Dam, Ellen, Cowley, Mark, Han, Ting-Li, Balaban, Seher, Pajic, Marina, Pinese, Mark, Iconomou, Mary, Shearer, Robert F., McKenna, Jessie, Miller, David, Waddell, Nicola, Pearson, John V., Grimmond, Sean M., Sazanov, Leonid, Biankin, Andrew V., Villas-Boas, Silas, Hoy, Andrew J., Turner, Nigel, Saunders, Darren N.
Publicado 2017

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

por Kennedy, Sean P., Han, Jeremy Z. R., Portman, Neil, Nobis, Max, Hastings, Jordan F., Murphy, Kendelle J., Latham, Sharissa L., Cadell, Antonia L., Miladinovic, Dushan, Marriott, Gabriella R., O’Donnell, Yolande E. I., Shearer, Robert F., Williams, James T., Munoz, Amaya Garcia, Cox, Thomas R., Watkins, D. Neil, Saunders, Darren N., Timpson, Paul, Lim, Elgene, Kolch, Walter, Croucher, David R.
Publicado 2019

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

por Xu, Hong, Di Antonio, Marco, McKinney, Steven, Mathew, Veena, Ho, Brandon, O'Neil, Nigel J., Santos, Nancy Dos, Silvester, Jennifer, Wei, Vivien, Garcia, Jessica, Kabeer, Farhia, Lai, Daniel, Soriano, Priscilla, Banáth, Judit, Chiu, Derek S., Yap, Damian, Le, Daniel D., Ye, Frank B., Zhang, Anni, Thu, Kelsie, Soong, John, Lin, Shu-chuan, Tsai, Angela Hsin Chin, Osako, Tomo, Algara, Teresa, Saunders, Darren N., Wong, Jason, Xian, Jian, Bally, Marcel B., Brenton, James D., Brown, Grant W., Shah, Sohrab P., Cescon, David, Mak, Tak W., Caldas, Carlos, Stirling, Peter C., Hieter, Phil, Balasubramanian, Shankar, Aparicio, Samuel
Publicado 2017