Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders

por Wang, Yi-Zhi, Savas, Jeffrey N.
Publicado 2018

Levetiracetam Treatment Normalizes Levels of Presynaptic Endocytosis Machinery and Restores Nonamyloidogenic APP Processing in App Knock-in Mice

por Rao, Nalini R., Savas, Jeffrey N.
Publicado 2021

The Dichotomous Role of Extracellular Vesicles in the Central Nervous System

por Graykowski, David R., Wang, Yi-Zhi, Upadhyay, Arun, Savas, Jeffrey N.
Publicado 2020

Striatal RGS7 Regulates Depression-Related Behaviors and Stress-Induced Reinstatement of Cocaine Conditioned Place Preference

por Sutton, Laurie P., Khalatyan, Natalia, Savas, Jeffrey N., Martemyanov, Kirill A.
Publicado 2021

Long-lived mitochondrial cristae proteins in mouse heart and brain

por Bomba-Warczak, Ewa, Edassery, Seby L., Hark, Timothy J., Savas, Jeffrey N.
Publicado 2021

Analysis of URI Nuclear Interaction with RPB5 and Components of the R2TP/Prefoldin-Like Complex

por Mita, Paolo, Savas, Jeffrey N., Ha, Susan, Djouder, Nabil, Yates, John R., Logan, Susan K.
Publicado 2013

Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry

por Liu, Pan, Edassery, Seby Louis, Ali, Laith, Thomson, Benjamin R, Savas, Jeffrey N, Jin, Jing
Publicado 2019

Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome

por Yoon, Sehyoun, Piguel, Nicolas H., Khalatyan, Natalia, Dionisio, Leonardo E., Savas, Jeffrey N., Penzes, Peter
Publicado 2021

Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons

por Ma, Bin, Savas, Jeffrey N., Yu, Man-Shan, Culver, Brady P., Chao, Moses V., Tanese, Naoko
Publicado 2011

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

por Upadhyay, Arun, Chhangani, Deepak, Rao, Nalini R., Kofler, Julia, Vassar, Robert, Rincon-Limas, Diego E., Savas, Jeffrey N.
Publicado 2023

Critical Period Inhibition of NKCC1 Rectifies Synapse Plasticity in the Somatosensory cortex and Restores Adult Tactile Response Maps in Fragile X Mice

por He, Qionger, Arroyo, Erica D, Smukowski, Samuel N, Xu, Jian, Piochon, Claire, Savas, Jeffrey N, Portera-Cailliau, Carlos, Contractor, Anis
Publicado 2018

β-Catenin/Tcf7l2–dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer

por Zhao, Zibo, Wang, Lu, Bartom, Elizabeth, Marshall, Stacy, Rendleman, Emily, Ryan, Caila, Shilati, Anthony, Savas, Jeffrey, Chandel, Navdeep, Shilatifard, Ali
Publicado 2019

Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome

por Yoon, Sehyoun, Dos Santos, Marc, Forrest, Marc P., Pratt, Christopher P., Khalatyan, Natalia, Mohler, Peter J., Savas, Jeffrey N., Penzes, Peter
Publicado 2023

Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

por Bomba-Warczak, Ewa K., Velez, Karen M., Zhou, Luhan T, Guillermier, Christelle, Edassery, Seby, Steinhauser, Matthew, Savas, Jeffrey N., Duncan, Francesca E.
Publicado 2023

Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex

por McClatchy, Daniel B., Savas, Jeffrey N., Martínez-Bartolomé, Salvador, Park, Sung Kyu, Maher, Pamela, Powell, Susan B., Yates, John R.
Publicado 2015

Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase

por Jha, Sujata, Rollins, Madeline G., Fuchs, Gabriele, Procter, Dean J., Hall, Elizabeth A., Cozzolino, Kira, Sarnow, Peter, Savas, Jeffrey N., Walsh, Derek
Publicado 2017

Sirt1 mediates neuroprotection from mutant huntingtin by activation of TORC1 and CREB transcriptional pathway

por Cohen, Dena E., Cui, Libin, Supinski, Andrea, Savas, Jeffrey N., Mazzulli, Joseph R., Yates, John R., Bordone, Laura, Guarente, Leonard P., Krainc, Dimitri
Publicado 2011

Noise Exposures Causing Hearing Loss Generate Proteotoxic Stress and Activate the Proteostasis Network

por Jongkamonwiwat, Nopporn, Ramirez, Miguel A., Edassery, Seby, Wong, Ann C.Y., Yu, Jintao, Abbott, Tirzah, Pak, Kwang, Ryan, Allen F., Savas, Jeffrey N.
Publicado 2020

A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism

por Wang, Lu, Collings, Clayton K., Zhao, Zibo, Cozzolino, Kira Alia, Ma, Quanhong, Liang, Kaiwei, Marshall, Stacy A., Sze, Christie C., Hashizume, Rintaro, Savas, Jeffrey Nicholas, Shilatifard, Ali
Publicado 2017

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function

por Kim, Jean J., Savas, Jeffrey N., Miller, Meghan T., Hu, Xindao, Carromeu, Cassiano, Lavallée-Adam, Mathieu, Freitas, Beatriz C. G., Muotri, Alysson R., Yates, John R., Ghosh, Anirvan
Publicado 2019