Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

por Saveljeva, S, Mc Laughlin, S L, Vandenabeele, P, Samali, A, Bertrand, M J M
Publicado 2015

Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions

por Deegan, Shane, Saveljeva, Svetlana, Logue, Susan E, Pakos-Zebrucka, Karolina, Gupta, Sanjeev, Vandenabeele, Peter, Bertrand, Mathieu JM, Samali, Afshin
Publicado 2014

Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

por Saveljeva, Svetlana, Cleary, Patricia, Mnich, Katarzyna, Ayo, Abiodun, Pakos-Zebrucka, Karolina, Patterson, John B, Logue, Susan E., Samali, Afshin
Publicado 2016

Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

por Pagano, Ester, Elias, Joshua E, Schneditz, Georg, Saveljeva, Svetlana, Holland, Lorraine M, Borrelli, Francesca, Karlsen, Tom H, Kaser, Arthur, Kaneider, Nicole C
Publicado 2022

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

por Kennedy, Donna, Mnich, Katarzyna, Oommen, Deepu, Chakravarthy, Reka, Almeida-Souza, Leonardo, Krols, Michiel, Saveljeva, Svetlana, Doyle, Karen, Gupta, Sanjeev, Timmerman, Vincent, Janssens, Sophie, Gorman, Adrienne M, Samali, Afshin
Publicado 2017

Impaired Autophagy in CD11b(+) Dendritic Cells Expands CD4(+) Regulatory T Cells and Limits Atherosclerosis in Mice

por Clement, Marc, Raffort, Juliette, Lareyre, Fabien, Tsiantoulas, Dimitrios, Newland, Stephen, Lu, Yuning, Masters, Leanne, Harrison, James, Saveljeva, Svetlana, Ma, Marcella K.L., Ozsvar-Kozma, Maria, Lam, Brian Y.H., Yeo, Giles S.H., Binder, Christoph J., Kaser, Arthur, Mallat, Ziad
Publicado 2019

Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells

por Powell, Nick, Pantazi, Eirini, Pavlidis, Polychronis, Tsakmaki, Anastasia, Li, Katherine, Yang, Feifei, Parker, Aimee, Pin, Carmen, Cozzetto, Domenico, Minns, Danielle, Stolarczyk, Emilie, Saveljeva, Svetlana, Mohamed, Rami, Lavender, Paul, Afzali, Behdad, Digby-Bell, Jonathan, Tjir-Li, Tsui, Kaser, Arthur, Friedman, Joshua, MacDonald, Thomas T, Bewick, Gavin A, Lord, Graham M
Publicado 2020

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

por Aden, Konrad, Tran, Florian, Ito, Go, Sheibani-Tezerji, Raheleh, Lipinski, Simone, Kuiper, Jan W., Tschurtschenthaler, Markus, Saveljeva, Svetlana, Bhattacharyya, Joya, Häsler, Robert, Bartsch, Kareen, Luzius, Anne, Jentzsch, Marlene, Falk-Paulsen, Maren, Stengel, Stephanie T., Welz, Lina, Schwarzer, Robin, Rabe, Björn, Barchet, Winfried, Krautwald, Stefan, Hartmann, Gunther, Pasparakis, Manolis, Blumberg, Richard S., Schreiber, Stefan, Kaser, Arthur, Rosenstiel, Philip
Publicado 2018

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

por Tschurtschenthaler, Markus, Adolph, Timon E., Ashcroft, Jonathan W., Niederreiter, Lukas, Bharti, Richa, Saveljeva, Svetlana, Bhattacharyya, Joya, Flak, Magdalena B., Shih, David Q., Fuhler, Gwenny M., Parkes, Miles, Kohno, Kenji, Iwawaki, Takao, Janneke van der Woude, C., Harding, Heather P., Smith, Andrew M., Peppelenbosch, Maikel P., Targan, Stephan R., Ron, David, Rosenstiel, Philip, Blumberg, Richard S., Kaser, Arthur
Publicado 2017

A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

por Saveljeva, Svetlana, Sewell, Gavin W., Ramshorn, Katharina, Cader, M. Zaeem, West, James A., Clare, Simon, Haag, Lea-Maxie, de Almeida Rodrigues, Rodrigo Pereira, Unger, Lukas W., Iglesias-Romero, Ana Belén, Holland, Lorraine M., Bourges, Christophe, Md-Ibrahim, Muhammad N., Jones, James O., Blumberg, Richard S., Lee, James C., Kaneider, Nicole C., Lawley, Trevor D., Bradley, Allan, Dougan, Gordon, Kaser, Arthur
Publicado 2022

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

por Cader, M. Zaeem, de Almeida Rodrigues, Rodrigo Pereira, West, James A., Sewell, Gavin W., Md-Ibrahim, Muhammad N., Reikine, Stephanie, Sirago, Giuseppe, Unger, Lukas W., Inglesias-Romero, Ana Belén, Ramshorn, Katharina, Haag, Lea-Maxie, Saveljeva, Svetlana, Ebel, Jana-Fabienne, Rosenstiel, Philip, Kaneider, Nicole C., Lee, James C., Lawley, Trevor D., Bradley, Allan, Dougan, Gordon, Modis, Yorgo, Griffin, Julian L., Kaser, Arthur
Publicado 2020

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

por Cader, M. Zaeem, de Almeida Rodrigues, Rodrigo Pereira, West, James A., Sewell, Gavin W., Md-Ibrahim, Muhammad N., Reikine, Stephanie, Sirago, Giuseppe, Unger, Lukas W., Iglesias-Romero, Ana Belén, Ramshorn, Katharina, Haag, Lea-Maxie, Saveljeva, Svetlana, Ebel, Jana-Fabienne, Rosenstiel, Philip, Kaneider, Nicole C., Lee, James C., Lawley, Trevor D., Bradley, Allan, Dougan, Gordon, Modis, Yorgo, Griffin, Julian L., Kaser, Arthur
Publicado 2020