HNSCC: Tumour Antigens and Their Targeting by Immunotherapy

por von Witzleben, Adrian, Wang, Chuan, Laban, Simon, Savelyeva, Natalia, Ottensmeier, Christian H.
Publicado 2020

Targeting Head and Neck Cancer by Vaccination

por Wang, Chuan, Dickie, James, Sutavani, Ruhcha V., Pointer, Catherine, Thomas, Gareth J., Savelyeva, Natalia
Publicado 2018

Safety and Immunogenicity of Combined DNA-Polyethylenimine and Oral Bacterial Idiotypic Vaccine for Patients with B-Cell Non-Hodgkin Lymphoma: A Pilot Study

por Meleshko, Alexander, Piatrouskaya, Nadzeya, Vashkevich, Katsiaryna, Lutskovich, Dzmitry, Wang, Chuan, Dormeshkin, Dmitri, Savelyeva, Natalia, Katsin, Mikalai
Publicado 2022

Plant Virus Particles Carrying Tumour Antigen Activate TLR7 and Induce High Levels of Protective Antibody

por Jobsri, Jantipa, Allen, Alex, Rajagopal, Deepa, Shipton, Michael, Kanyuka, Kostya, Lomonossoff, George P., Ottensmeier, Christian, Diebold, Sandra S., Stevenson, Freda K., Savelyeva, Natalia
Publicado 2015

A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer

por Chotprakaikiat, Warayut, Allen, Alex, Bui-Minh, Duc, Harden, Elena, Jobsri, Jantipa, Cavallo, Federica, Gleba, Yuri, Stevenson, Freda K., Ottensmeier, Christian, Klimyuk, Victor, Savelyeva, Natalia
Publicado 2016

Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model

por Allen, Alex, Wang, Chuan, Caproni, Lisa J., Sugiyarto, Gessa, Harden, Elena, Douglas, Leon R., Duriez, Patrick J., Karbowniczek, Kinga, Extance, Jon, Rothwell, Paul J., Orefo, Ifeayinwa, Tite, John P., Stevenson, Freda K., Ottensmeier, Christian H., Savelyeva, Natalia
Publicado 2018

Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors

por Wood, Oliver, Woo, Jeongmin, Seumois, Gregory, Savelyeva, Natalia, McCann, Katy J., Singh, Divya, Jones, Terry, Peel, Lailah, Breen, Michael S., Ward, Matthew, Martin, Eva Garrido, Sanchez-Elsner, Tilman, Thomas, Gareth, Vijayanand, Pandurangan, Woelk, Christopher H., King, Emma, Ottensmeier, Christian
Publicado 2016

Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer

por McCann, Katy, von Witzleben, Adrian, Thomas, Jaya, Wang, Chuan, Wood, Oliver, Singh, Divya, Boukas, Konstantinos, Bendjama, Kaidre, Silvestre, Nathalie, Nielsen, Finn Cilius, Thomas, Gareth, Sanchez-Elsner, Tilman, Greenbaum, Jason, Schoenberger, Stephen, Peters, Bjoern, Vijayanand, Pandurangan, Savelyeva, Natalia, Ottensmeier, Christian
Publicado 2022

Transcriptional analysis highlights three distinct immune profiles of high-risk oral epithelial dysplasia

por Gan, Chai Phei, Lee, Bernard Kok Bang, Lau, Shin Hin, Kallarakkal, Thomas George, Zaini, Zuraiza Mohamad, Lye, Bryan Kit Weng, Zain, Rosnah Binti, Sathasivam, Hans Prakash, Yeong, Joe Poh Sheng, Savelyeva, Natalia, Thomas, Gareth, Ottensmeier, Christian H., Ariffin, Hany, Cheong, Sok Ching, Lim, Kue Peng
Publicado 2022

ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance

por Mellone, Massimiliano, Piotrowska, Klaudia, Venturi, Giulia, James, Lija, Bzura, Aleksandra, Lopez, Maria A., James, Sonya, Wang, Chuan, Ellis, Matthew J., Hanley, Christopher J., Buckingham, Josephine F., Cox, Kerry L., Hughes, Gareth, Valge-Archer, Viia, King, Emma V., Beers, Stephen A., Jaquet, Vincent, Jones, George D.D., Savelyeva, Natalia, Sayan, Emre, Parsons, Jason L., Durant, Stephen, Thomas, Gareth J.
Publicado 2022

DNA Vaccines Targeting Novel Cancer-Associated Antigens Frequently Expressed in Head and Neck Cancer Enhance the Efficacy of Checkpoint Inhibitor

por Wang, Chuan, Zainal, Nur Syafinaz, Chai, San Jiun, Dickie, James, Gan, Chai Phei, Zulaziz, Natasha, Lye, Bryan Kit Weng, Sutavani, Ruhcha V., Ottensmeier, Christian H., King, Emma V., Abraham, Mannil Thomas, Ismail, Siti Mazlipah binti, Lau, Shin Hin, Kallarakkal, Thomas George, Mun, Kein Seong, Zain, Rosnah binti, Abdul Rahman, Zainal Ariff, Thomas, Gareth J., Cheong, Sok Ching, Savelyeva, Natalia, Lim, Kue Peng
Publicado 2021