Transcriptional enhancers in development and disease

por Sakabe, Noboru Jo, Savic, Daniel, Nobrega, Marcelo A
Publicado 2012

An in vivo cis-Regulatory Screen at the Type 2 Diabetes Associated TCF7L2 Locus Identifies Multiple Tissue-Specific Enhancers

por Savic, Daniel, Bell, Graeme I., Nobrega, Marcelo A.
Publicado 2012

Mapping genome-wide transcription factor binding sites in frozen tissues

por Savic, Daniel, Gertz, Jason, Jain, Preti, Cooper, Gregory M, Myers, Richard M
Publicado 2013

Modulation of Tcf7l2 Expression Alters Behavior in Mice

por Savic, Daniel, Distler, Margaret G., Sokoloff, Greta, Shanahan, Nancy A., Dulawa, Stephanie C., Palmer, Abraham A., Nobrega, Marcelo A.
Publicado 2011

A genome-wide interactome of DNA-associated proteins in the human liver

por Ramaker, Ryne C., Savic, Daniel, Hardigan, Andrew A., Newberry, Kimberly, Cooper, Gregory M., Myers, Richard M., Cooper, Sara J.
Publicado 2017

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

por Savic, Daniel, Partridge, E. Christopher, Newberry, Kimberly M., Smith, Sophia B., Meadows, Sarah K., Roberts, Brian S., Mackiewicz, Mark, Mendenhall, Eric M., Myers, Richard M.
Publicado 2015

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

por Savic, Daniel, Roberts, Brian S., Carleton, Julia B., Partridge, E. Christopher, White, Michael A., Cohen, Barak A., Cooper, Gregory M., Gertz, Jason, Myers, Richard M.
Publicado 2015

Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice

por Bailey, Kathleen A., Savic, Daniel, Zielinski, Mark, Park, Soo-Young, Wang, Ling-jia, Witkowski, Piotr, Brady, Matthew, Hara, Manami, Bell, Graeme I., Nobrega, Marcelo A.
Publicado 2015

Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf

por Pham, Duy, Moseley, Carson E., Gao, Min, Savic, Daniel, Winstead, Colleen J., Sun, Mengxi, Kee, Barbara L., Myers, Richard M., Weaver, Casey T., Hatton, Robin D.
Publicado 2019

Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

por Savic, Daniel, Ramaker, Ryne C., Roberts, Brian S., Dean, Emma C., Burwell, Todd C., Meadows, Sarah K., Cooper, Sara J., Garabedian, Michael J., Gertz, Jason, Myers, Richard M.
Publicado 2016

Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia

por Bergeron, Brennan P., Barnett, Kelly R., Bhattarai, Kashi Raj, Mobley, Robert J., Hansen, Baranda S., Brown, Anthony, Kodali, Kiran, High, Anthony A., Jeha, Sima, Pui, Ching-Hon, Peng, Junmin, Pruett-Miller, Shondra M., Savic, Daniel
Publicado 2023

Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia

por Zhao, Xujie, Wang, Ping, Diedrich, Jonathan D., Smart, Brandon, Reyes, Noemi, Yoshimura, Satoshi, Zhang, Jingliao, Yang, Wentao, Barnett, Kelly, Xu, Beisi, Li, Zhenhua, Huang, Xin, Yu, Jiyang, Crews, Kristine, Yeoh, Allen Eng Juh, Konopleva, Marina, Wei, Chia-Lin, Pui, Ching-Hon, Savic, Daniel, Yang, Jun J.
Publicado 2022

Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia

por Bergeron, Brennan P., Diedrich, Jonathan D., Zhang, Yang, Barnett, Kelly R., Dong, Qian, Ferguson, Daniel C., Autry, Robert J., Yang, Wenjian, Hansen, Baranda S., Smith, Colton, Crews, Kristine R., Fan, Yiping, Pui, Ching-Hon, Pruett-Miller, Shondra M., Relling, Mary V., Yang, Jun J., Li, Chunliang, Evans, William E., Savic, Daniel
Publicado 2022

Occupancy maps of 208 chromatin-associated proteins in one human cell type

por Partridge, E. Christopher, Chhetri, Surya B., Prokop, Jeremy W., Ramaker, Ryne C., Jansen, Camden S., Goh, Say-Tar, Mackiewicz, Mark, Newberry, Kimberly M., Brandsmeier, Laurel A., Meadows, Sarah K., Messer, C. Luke, Hardigan, Andrew A., Coppola, Candice J., Dean, Emma C., Jiang, Shan, Savic, Daniel, Mortazavi, Ali, Wold, Barbara J., Myers, Richard M., Mendenhall, Eric M.
Publicado 2020

Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures

por Barnett, Kelly R., Mobley, Robert J., Diedrich, Jonathan D., Bergeron, Brennan P., Bhattarai, Kashi Raj, Yang, Wenjian, Crews, Kristine R., Manring, Christopher S., Jabbour, Elias, Paietta, Elisabeth, Litzow, Mark R., Kornblau, Steven M., Stock, Wendy, Inaba, Hiroto, Jeha, Sima, Pui, Ching-Hon, Mullighan, Charles G., Relling, Mary V., Yang, Jun J., Evans, William E., Savic, Daniel
Publicado 2023

Genomic regulation of invasion by STAT3 in triple negative breast cancer

por McDaniel, Joy M., Varley, Katherine E., Gertz, Jason, Savic, Daniel S., Roberts, Brian S., Bailey, Sarah K., Shevde, Lalita A., Ramaker, Ryne C., Lasseigne, Brittany N., Kirby, Marie K., Newberry, Kimberly M., Christopher Partridge, E ., Jones, Angela L., Boone, Braden, Levy, Shawn E., Oliver, Patsy G., Sexton, Katherine C., Grizzle, William E., Forero, Andres, Buchsbaum, Donald J., Cooper, Sara J., Myers, Richard M.
Publicado 2016

Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment

por Bhattarai, Kashi Raj, Mobley, Robert J., Barnett, Kelly R., Ferguson, Daniel C., Hansen, Baranda S., Diedrich, Jonathan D., Bergeron, Brennan P., Yang, Wenjian, Crews, Kristine R., Manring, Christopher S., Jabbour, Elias, Paietta, Elisabeth, Litzow, Mark R., Kornblau, Steven M., Stock, Wendy, Inaba, Hiroto, Jeha, Sima, Pui, Ching-Hon, Cheng, Cheng, Pruett-Miller, Shondra M., Relling, Mary V., Yang, Jun J., Evans, William E., Savic, Daniel
Publicado 2023

Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia

por Ferguson, Daniel C., McCorkle, J. Robert, Barnett, Kelly R., Bonten, Erik J., Bergeron, Brennan P., Bhattarai, Kashi Raj, Yang, Wenjian, Smith, Colton, Hansen, Baranda S., Bajpai, Richa, Dong, Qian, Autry, Robert J., Gocho, Yoshihiro, Diedrich, Jonathan D., Crews, Kristine R., Pruett-Miller, Shondra M., Roberts, Kathryn G., Stock, Wendy, Mullighan, Charles G., Inaba, Hiroto, Jeha, Sima, Pui, Ching-Hon, Yang, Jun J., Relling, Mary V., Evans, William E., Savic, Daniel
Publicado 2022

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells

por Paugh, Steven W., Bonten, Erik J., Savic, Daniel, Ramsey, Laura B., Thierfelder, William E., Gurung, Prajwal, Malireddi, R. K. Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R., Laudermilk, Lucas T., Panetta, John C., McCorkle, J. Robert, Fan, Yiping, Crews, Kristine R., Stocco, Gabriele, Wilkinson, Mark R., Ferreira, Antonio M., Cheng, Cheng, Yang, Wenjian, Karol, Seth E., Fernandez, Christian A., Diouf, Barthelemy, Smith, Colton, Hicks, J. Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J., Holmfeldt, Linda, Mullighan, Charles G., den Boer, Monique L., Pieters, Rob, Jeha, Sima, Dunwell, Thomas L., Latif, Farida, Bhojwani, Deepa, Carroll, William L., Pui, Ching-Hon, Myers, Richard M., Guy, R. Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V., Evans, William E.
Publicado 2015