Is Glycemic Control the Secret to Tuberculosis Control?

por Huddart, Sophie, Savic, Rada M., Cattamanchi, Adithya
Publicado 2021

The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials

por Vernon, Andrew, Fielding, Katherine, Savic, Rada, Dodd, Lori, Nahid, Payam
Publicado 2019

Analysis of Dynamic Efficacy Endpoints of the Nix-TB Trial

por Solans, Belén P, Imperial, Marjorie Z, Olugbosi, Morounfolu, Savic, Rada M
Publicado 2023

Mechanistic Modeling of Mycobacterium tuberculosis Infection in Murine Models for Drug and Vaccine Efficacy Studies

por Zhang, Nan, Strydom, Natasha, Tyagi, Sandeep, Soni, Heena, Tasneen, Rokeya, Nuermberger, Eric L., Savic, Rada M.
Publicado 2020

Variable piperaquine exposure significantly impacts protective efficacy of monthly dihydroartemisinin-piperaquine for the prevention of malaria in Ugandan children

por Sundell, Kerstin, Jagannathan, Prasanna, Huang, Liusheng, Bigira, Victor, Kapisi, James, Kakuru, Mary M., Savic, Rada, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca
Publicado 2015

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

por Blanc, Landry, Daudelin, Isaac B, Podell, Brendan K, Chen, Pei-Yu, Zimmerman, Matthew, Martinot, Amanda J, Savic, Rada M, Prideaux, Brendan, Dartois, Véronique
Publicado 2018

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

por Garcia-Prats, Anthony J., Schaaf, H. Simon, Draper, Heather R., Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C., Savic, Rada M.
Publicado 2019

Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs

por Ernest, Jacqueline P., Goh, Janice Jia Ni, Strydom, Natasha, Wang, Qianwen, van Wijk, Rob C., Zhang, Nan, Deitchman, Amelia, Nuermberger, Eric, Savic, Rada M.
Publicado 2023

Pharmacodynamic Correlates of Linezolid Activity and Toxicity in Murine Models of Tuberculosis

por Bigelow, Kristina M, Deitchman, Amelia N, Li, Si-Yang, Barnes-Boyle, Kala, Tyagi, Sandeep, Soni, Heena, Dooley, Kelly E, Savic, Rada M, Nuermberger, Eric L
Publicado 2020

Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer

por Knox, Susan J., Jayachandran, Priya, Keeling, Christine A., Stevens, Kathryn J., Sandhu, Navjot, Stamps-DeAnda, Stacy Leanne, Savic, Rada, Shura, Lei, Buyyounouski, Mark K., Grimes, Kevin
Publicado 2019

Coronavirus Disease 2019 (COVID-19) Pharmacologic Treatments for Children: Research Priorities and Approach to Pediatric Studies

por Garcia-Prats, Anthony J, Salazar-Austin, Nicole, Conway, James H, Radtke, Kendra, LaCourse, Sylvia M, Maleche-Obimbo, Elizabeth, Hesseling, Anneke C, Savic, Rada M, Nachman, Sharon
Publicado 2020

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

por Imperial, Marjorie Z., Nahid, Payam, Phillips, Patrick P. J., Davies, Geraint R., Fielding, Katherine, Hanna, Debra, Hermann, David, Wallis, Robert S., Johnson, John L., Lienhardt, Christian, Savic, Rada M.
Publicado 2018

Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

por Imperial, Marjorie Z., Nahid, Payam, Phillips, Patrick P. J., Davies, Geraint R., Fielding, Katherine, Hanna, Debra, Hermann, David, Wallis, Robert S., Johnson, John L., Lienhardt, Christian, Savic, Rada M.
Publicado 2018

Population Pharmacokinetic Method to Predict Within-Subject Variability Using Single-Period Clinical Data

por Kang, Won-ho, Lee, Jae-yeon, Chae, Jung-woo, Lee, Kyeong-Ryoon, Baek, In-hwan, Kim, Min-Soo, Back, Hyun-moon, Jung, Sangkeun, Shaffer, Craig, Savic, Rada, Yun, Hwi-yeol
Publicado 2021

QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Stud...

por Ali, Ali Mohamed, Radtke, Kendra K., Hesseling, Anneke C., Winckler, Jana, Schaaf, H. Simon, Draper, Heather R., Solans, Belén P., van der Laan, Louvina, Hughes, Jennifer, Fourie, Barend, Nielsen, James, Garcia-Prats, Anthony J., Savic, Rada M.
Publicado 2023

Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children

por Wallender, Erika, Ali, Ali Mohamed, Hughes, Emma, Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary Kakuru, Opira, Bishop, Whalen, Meghan, Huang, Liusheng, Duvalsaint, Marvin, Legac, Jenny, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.
Publicado 2021

Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation

por Brooks, Jordan T., Solans, Belen P., Lu, Ying, Kharbanda, Sandhya, Dvorak, Christopher C., Lalefar, Nahal, Long, Susie, Gupta, Ashish O., Horn, Biljana, Lamba, Jatinder K., Huang, Liusheng, Apsel-Winger, Beth, Keizer, Ron J., Savic, Rada, Long-Boyle, Janel
Publicado 2022

Identifying patients with multidrug-resistant tuberculosis who may benefit from shorter durations of treatment

por Winters, Nicholas, Schnitzer, Mireille E., Campbell, Jonathon R., Ripley, Susannah, Winston, Carla, Savic, Rada, Ahmad, Nafees, Bisson, Gregory, Dheda, Keertan, Esmail, Ali, Gegia, Medea, Monedero, Ignacio, Dalcolmo, Margareth Pretti, Rodrigues, Denise, Singla, Rupak, Yim, Jae-Joon, Menzies, Dick
Publicado 2023

Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments

por Dide-Agossou, Christian, Bauman, Allison A., Ramey, Michelle E., Rossmassler, Karen, Al Mubarak, Reem, Pauly, Samantha, Voskuil, Martin I., Garcia-Cremades, Maria, Savic, Rada M., Nahid, Payam, Moore, Camille M., Tasneen, Rokeya, Nuermberger, Eric L., Robertson, Gregory T., Walter, Nicholas D.
Publicado 2022

Pharmacokinetics and Safety of 3 Months of Weekly Rifapentine and Isoniazid for Tuberculosis Prevention in Pregnant Women

por Mathad, Jyoti S, Savic, Rada, Britto, Paula, Jayachandran, Priya, Wiesner, Lubbe, Montepiedra, Grace, Norman, Jennifer, Zhang, Nan, Townley, Ellen, Chakhtoura, Nahida, Bradford, Sarah, Patil, Sandesh, Popson, Stephanie, Chipato, Tsungai, Rouzier, Vanessa, Langat, Deborah, Chalermchockcharoentkit, Amphan, Kamthunzi, Portia, Gupta, Amita, Dooley, Kelly E
Publicado 2021