Ubiquitin receptors play redundant roles in the proteasomal degradation of the p53 repressor MDM2

por Sparks, Alison, Kelly, Christopher J., Saville, Mark K.
Publicado 2022

Helium-oxygen reduces the production of carbon dioxide during weaning from mechanical ventilation

por Flynn, Gordon, Mandersloot, Gerlinde, Healy, Marie, Saville, Mark, McAuley, Daniel F
Publicado 2010

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

por Hepburn, Lydia A., McHugh, Angela, Fernandes, Kenneth, Boag, Garry, Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicado 2018

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity

por McHugh, Angela, Fernandes, Kenneth, South, Andrew P., Mellerio, Jemima E., Salas-Alanís, Julio C., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicado 2018

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

por McHugh, Angela, Fernandes, Kenneth, Chinner, Nerime, Ibrahim, Adel F.M., Garg, Amit K., Boag, Garry, Hepburn, Lydia A., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicado 2020

Suppression of mutant Kirsten-RAS (KRAS(G12D))-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6

por Kidger, Andrew M., Saville, Mark K., Rushworth, Linda K., Davidson, Jane, Stellzig, Julia, Ono, Motoharu, Kuebelsbeck, Ludwig A., Janssen, Klaus-Peter, Holzmann, Bernhard, Morton, Jennifer P., Sansom, Owen J., Caunt, Christopher J., Keyse, Stephen M.
Publicado 2022