Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis

por DiMarco, Giuliana M., Harris, Breanna N., Savonenko, Alena V., Soto, Paul L.
Publicado 2023

Hydroxyurea Improves Spatial Memory and Cognitive Plasticity in Mice and Has a Mild Effect on These Parameters in a Down Syndrome Mouse Model

por Brose, Rebecca Deering, Savonenko, Alena, Devenney, Benjamin, Smith, Kirby D., Reeves, Roger H.
Publicado 2019

Speaker 2: Gwenn Smith, USA

por Smith, Gwenn S., Barrett, Frederick S., Savonenko, Alena, Zhou, Yun, Wong, Dean F., Workman, Clifford I.
Publicado 2016

Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression

por Smith-Hicks, Constance L., Cai, Peiling, Savonenko, Alena V., Reeves, Roger H., Worley, Paul F.
Publicado 2017

Sleep and circadian rhythm disruption by NPTX2 loss of function

por Roh, Seung-Eon, Xiao, Meifang, Delgado, Ana, Kwak, Chuljung, Savonenko, Alena, Bakker, Arnold, Kwon, Hyung-Bae, Worley, Paul
Publicado 2023

Intranasal post-cardiac arrest treatment with orexin-A facilitates arousal from coma and ameliorates neuroinflammation

por Modi, Hiren R., Wang, Qihong, GD, Sahithi, Sherman, David, Greenwald, Elliot, Savonenko, Alena V., Geocadin, Romergryko G., Thakor, Nitish V.
Publicado 2017

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

por LaClair, Katherine D, Manaye, Kebreten F, Lee, Dexter L, Allard, Joanne S, Savonenko, Alena V, Troncoso, Juan C, Wong, Philip C
Publicado 2013

Correction: treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

por LaClair, Katherine D, Manaye, Kebreten F, Lee, Dexter L, Allard, Joanne S, Savonenko, Alena V, Troncoso, Juan C, Wong, Philip C
Publicado 2013

Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates

por Gao, Feng J., Klinedinst, Donna, Fernandez, Fabian-Xosé, Cheng, Bei, Savonenko, Alena, Devenney, Benjamin, Li, Yicong, Wu, Dan, Pomper, Martin G., Reeves, Roger H.
Publicado 2021

Positron emission tomography imaging of serotonin degeneration and beta-amyloid deposition in late-life depression evaluated with multi-modal partial least squares

por Smith, Gwenn S., Workman, Clifford I., Protas, Hillary, Su, Yi, Savonenko, Alena, Kuwabara, Hiroto, Gould, Neda F., Kraut, Michael, Joo, Jin Hui, Nandi, Ayon, Avramopoulos, Dimitri, Reiman, Eric M., Chen, Kewei
Publicado 2021

Molecular imaging of the association between serotonin degeneration and beta-amyloid deposition in mild cognitive impairment

por Smith, Gwenn S., Protas, Hillary, Kuwabara, Hiroto, Savonenko, Alena, Nassery, Najlla, Gould, Neda F., Kraut, Michael, Avramopoulos, Dimitri, Holt, Daniel, Dannals, Robert F., Nandi, Ayon, Su, Yi, Reiman, Eric M., Chen, Kewei
Publicado 2023

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

por Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G, Borchelt, David R
Publicado 2005

Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation

por Savonenko, Alena V., Melnikova, Tatiana, Wang, Yuchuan, Ravert, Hayden, Gao, Yongjun, Koppel, Jeremy, Lee, Deidre, Pletnikova, Olga, Cho, Eugenia, Sayyida, Nuzhat, Hiatt, Andrew, Troncoso, Juan, Davies, Peter, Dannals, Robert F., Pomper, Martin G., Horti, Andrew G.
Publicado 2015

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

por Singh, Balvindar, Covelo, Ana, Martell-Martínez, Héctor, Nanclares, Carmen, Sherman, Mathew A., Okematti, Emmanuel, Meints, Joyce, Teravskis, Peter J., Gallardo, Christopher, Savonenko, Alena V., Benneyworth, Michael A., Lesné, Sylvain E., Liao, Dezhi, Araque, Alfonso, Lee, Michael K.
Publicado 2019

Regional amyloid correlates of cognitive performance in ageing and mild cognitive impairment

por Stevens, Daniel A., Workman, Clifford I., Kuwabara, Hiroto, Butters, Meryl A., Savonenko, Alena, Nassery, Najilla, Gould, Neda, Kraut, Michael, Joo, Jin Hui, Kilgore, Jessica, Kamath, Vidya, Holt, Daniel P., Dannals, Robert F., Nandi, Ayon, Onyike, Chiadi U., Smith, Gwenn S.
Publicado 2022

NPTX2 and cognitive dysfunction in Alzheimer’s Disease

por Xiao, Mei-Fang, Xu, Desheng, Craig, Michael T, Pelkey, Kenneth A, Chien, Chun-Che, Shi, Yang, Zhang, Juhong, Resnick, Susan, Pletnikova, Olga, Salmon, David, Brewer, James, Edland, Steven, Wegiel, Jerzy, Tycko, Benjamin, Savonenko, Alena, Reeves, Roger H, Troncoso, Juan C, McBain, Chris J, Galasko, Douglas, Worley, Paul F
Publicado 2017

A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function

por Xiao, Mei-Fang, Roh, Seung-Eon, Zhou, Jiechao, Chien, Chun-Che, Lucey, Brendan P., Craig, Michael T., Hayes, Lindsay N., Coughlin, Jennifer M., Leweke, F. Markus, Jia, Min, Xu, Desheng, Zhou, Weiqiang, Conover Talbot, C., Arnold, Don B., Staley, Melissa, Jiang, Cindy, Reti, Irving M., Sawa, Akira, Pelkey, Kenneth A., McBain, Chris J., Savonenko, Alena, Worley, Paul F.
Publicado 2021

A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21

por Kazuki, Yasuhiro, Gao, Feng J, Li, Yicong, Moyer, Anna J, Devenney, Benjamin, Hiramatsu, Kei, Miyagawa-Tomita, Sachiko, Abe, Satoshi, Kazuki, Kanako, Kajitani, Naoyo, Uno, Narumi, Takehara, Shoko, Takiguchi, Masato, Yamakawa, Miho, Hasegawa, Atsushi, Shimizu, Ritsuko, Matsukura, Satoko, Noda, Naohiro, Ogonuki, Narumi, Inoue, Kimiko, Matoba, Shogo, Ogura, Atsuo, Florea, Liliana D, Savonenko, Alena, Xiao, Meifang, Wu, Dan, Batista, Denise AS, Yang, Junhua, Qiu, Zhaozhu, Singh, Nandini, Richtsmeier, Joan T, Takeuchi, Takashi, Oshimura, Mitsuo, Reeves, Roger H
Publicado 2020