Conformational changes and CO(2)-induced channel gating in connexin26

por Brotherton, Deborah H., Savva, Christos G., Ragan, Timothy J., Dale, Nicholas, Cameron, Alexander D.
Publicado 2022

Structural characterization of ribosome recruitment and translocation by type IV IRES

por Murray, Jason, Savva, Christos G, Shin, Byung-Sik, Dever, Thomas E, Ramakrishnan, V, Fernández, Israel S
Publicado 2016

The topology of chromatin-binding domains in the NuRD deacetylase complex

por Millard, Christopher J, Fairall, Louise, Ragan, Timothy J, Savva, Christos G, Schwabe, John W R
Publicado 2020

Structural Insights into Clostridium perfringens Delta Toxin Pore Formation

por Huyet, Jessica, Naylor, Claire E., Savva, Christos G., Gibert, Maryse, Popoff, Michel R., Basak, Ajit K.
Publicado 2013

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein

por Bokori-Brown, Monika, Martin, Thomas G., Naylor, Claire E., Basak, Ajit K., Titball, Richard W., Savva, Christos G.
Publicado 2016

Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids()

por Fernandes da Costa, Sérgio P., Mot, Dorien, Bokori-Brown, Monika, Savva, Christos G., Basak, Ajit K., Van Immerseel, Filip, Titball, Richard W.
Publicado 2013

Identification of a Key Residue for Oligomerisation and Pore-Formation of Clostridium perfringens NetB

por Fernandes da Costa, Sérgio P., Savva, Christos G., Bokori-Brown, Monika, Naylor, Claire E., Moss, David S., Basak, Ajit K., Titball, Richard W.
Publicado 2014

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

por Nguyen, Thi Hoang Duong, Galej, Wojciech P., Bai, Xiao-chen, Savva, Christos G., Newman, Andrew J., Scheres, Sjors H. W., Nagai, Kiyoshi
Publicado 2015

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

por Hussain, Tanweer, Llácer, Jose L., Fernández, Israel S., Munoz, Antonio, Martin-Marcos, Pilar, Savva, Christos G., Lorsch, Jon R., Hinnebusch, Alan G., Ramakrishnan, V.
Publicado 2014

The pore structure of Clostridium perfringens epsilon toxin

por Savva, Christos G., Clark, Alice R., Naylor, Claire E., Popoff, Michel R., Moss, David S., Basak, Ajit K., Titball, Richard W., Bokori-Brown, Monika
Publicado 2019

Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens

por Savva, Christos G., Fernandes da Costa, Sérgio P., Bokori-Brown, Monika, Naylor, Claire E., Cole, Ambrose R., Moss, David S., Titball, Richard W., Basak, Ajit K.
Publicado 2013

Structure of a bacterial type IV secretion core complex at subnanometre resolution

por Rivera-Calzada, Angel, Fronzes, Rémi, Savva, Christos G, Chandran, Vidya, Lian, Pei W, Laeremans, Toon, Pardon, Els, Steyaert, Jan, Remaut, Han, Waksman, Gabriel, Orlova, Elena V
Publicado 2013

Clostridium perfringens epsilon toxin H149A mutant as a platform for receptor binding studies

por Bokori-Brown, Monika, Kokkinidou, Maria C, Savva, Christos G, Fernandes da Costa, Sérgio, Naylor, Claire E, Cole, Ambrose R, Moss, David S, Basak, Ajit K, Titball, Richard W
Publicado 2013

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding

por Bate, Neil, Savva, Christos G., Moody, Peter C. E., Brown, Edward A., Evans, Sian E., Ball, Jonathan K., Schwabe, John W. R., Sale, Julian E., Brindle, Nicholas P. J.
Publicado 2022

Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia

por Bokori-Brown, Monika, Hall, Charlotte A., Vance, Charlotte, Fernandes da Costa, Sérgio P., Savva, Christos G., Naylor, Claire E., Cole, Ambrose R., Basak, Ajit K., Moss, David S., Titball, Richard W.
Publicado 2014

Structure of the processive human Pol δ holoenzyme

por Lancey, Claudia, Tehseen, Muhammad, Raducanu, Vlad-Stefan, Rashid, Fahad, Merino, Nekane, Ragan, Timothy J., Savva, Christos G., Zaher, Manal S., Shirbini, Afnan, Blanco, Francisco J., Hamdan, Samir M., De Biasio, Alfredo
Publicado 2020

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

por Gruszczyk, Jakub, Grandvuillemin, Loïc, Lai-Kee-Him, Josephine, Paloni, Matteo, Savva, Christos G., Germain, Pierre, Grimaldi, Marina, Boulahtouf, Abdelhay, Kwong, Hok-Sau, Bous, Julien, Ancelin, Aurélie, Bechara, Cherine, Barducci, Alessandro, Balaguer, Patrick, Bourguet, William
Publicado 2022

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

por Song, Yun, Dagil, Lisbeth, Fairall, Louise, Robertson, Naomi, Wu, Mingxuan, Ragan, T.J., Savva, Christos G., Saleh, Almutasem, Morone, Nobuhiro, Kunze, Micha B.A., Jamieson, Andrew G., Cole, Philip A., Hansen, D. Flemming, Schwabe, John W.R.
Publicado 2020

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

por Turnbull, Robert E., Fairall, Louise, Saleh, Almutasem, Kelsall, Emma, Morris, Kyle L., Ragan, T. J., Savva, Christos G., Chandru, Aditya, Millard, Christopher J., Makarova, Olga V., Smith, Corinne J., Roseman, Alan M., Fry, Andrew M., Cowley, Shaun M., Schwabe, John W. R.
Publicado 2020