The Essential Co-Option of Uracil-DNA Glycosylases by Herpesviruses Invites Novel Antiviral Design

por Savva, Renos
Publicado 2020

Crystal structure of a KSHV–SOX–DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff

por Bagnéris, Claire, Briggs, Louise C., Savva, Renos, Ebrahimi, Bahram, Barrett, Tracey E.
Publicado 2011

A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping

por Earl, Christopher, Bagnéris, Claire, Zeman, Kara, Cole, Ambrose, Barrett, Tracey, Savva, Renos
Publicado 2018

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase

por Cole, Ambrose R., Ofer, Sapir, Ryzhenkova, Ksenia, Baltulionis, Gediminas, Hornyak, Peter, Savva, Renos
Publicado 2013

Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering

por Javed, Abid, Villanueva, Hugo, Shataer, Shadikejiang, Vasciaveo, Sara, Savva, Renos, Orlova, Elena V.
Publicado 2021

A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase

por Muselmani, Wael, Kashif-Khan, Naail, Bagnéris, Claire, Santangelo, Rosalia, Williams, Mark A., Savva, Renos
Publicado 2023