Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer

por Marković, Iva, Savvides, Savvas N.
Publicado 2020

Engineering and crystal structure of a monomeric FLT3 ligand variant

por Pannecoucke, Erwin, Raes, Laurens, Savvides, Savvas N.
Publicado 2021

Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins

por Vergauwen, Bjorn, Van der Meeren, Ruben, Dansercoer, Ann, Savvides, Savvas N
Publicado 2011

Structure and oligomerization of the periplasmic domain of GspL from the type II secretion system of Pseudomonas aeruginosa

por Fulara, Aleksandra, Vandenberghe, Isabel, Read, Randy J., Devreese, Bart, Savvides, Savvas N.
Publicado 2018

Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity

por Detry, Sam, Andries, Julie, Bloch, Yehudi, Gabay, Cem, Clancy, Danielle M., Savvides, Savvas N.
Publicado 2022

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence

por Wen, Yurong, Behiels, Ester, Felix, Jan, Elegheert, Jonathan, Vergauwen, Bjorn, Devreese, Bart, Savvides, Savvas N.
Publicado 2014

Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish

por Mahony, Christopher B., Cacialli, Pietro, Pasche, Corentin, Monteiro, Rui, Savvides, Savvas N., Bertrand, Julien Y.
Publicado 2021

Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis

por Kozak, Sandra, Bloch, Yehudi, De Munck, Steven, Mikula, Aleksandra, Bento, Isabel, Savvides, Savvas N., Meijers, Rob
Publicado 2020

Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors

por Holgado, Aurora, Braun, Harald, Verstraete, Kenneth, Vanneste, Domien, Callewaert, Nico, Savvides, Savvas N., Afonina, Inna S., Beyaert, Rudi
Publicado 2020

Virtual screening for inhibitors of the human TSLP:TSLPR interaction

por Van Rompaey, Dries, Verstraete, Kenneth, Peelman, Frank, Savvides, Savvas N., Augustyns, Koen, Van Der Veken, Pieter, De Winter, Hans
Publicado 2017

Author Correction: Virtual screening for inhibitors of the human TSLP:TSLPR interaction

por Van Rompaey, Dries, Verstraete, Kenneth, Peelman, Frank, Savvides, Savvas N., Augustyns, Koen, Van Der Veken, Pieter, De Winter, Hans
Publicado 2018

EGOC inhibits TOROID polymerization by structurally activating TORC1

por Prouteau, Manoël, Bourgoint, Clélia, Felix, Jan, Bonadei, Lenny, Sadian, Yashar, Gabus, Caroline, Savvides, Savvas N., Gutsche, Irina, Desfosses, Ambroise, Loewith, Robbie
Publicado 2023

Unexpected complexity of the ammonia monooxygenase in archaea

por Hodgskiss, Logan H., Melcher, Michael, Kerou, Melina, Chen, Weiqiang, Ponce-Toledo, Rafael I., Savvides, Savvas N., Wienkoop, Stefanie, Hartl, Markus, Schleper, Christa
Publicado 2023

Correction to: Unexpected complexity of the ammonia monooxygenase in archaea

por Hodgskiss, Logan H., Melcher, Michael, Kerou, Melina, Chen, Weiqiang, Ponce-Toledo, Rafael I., Savvides, Savvas N., Wienkoop, Stefanie, Hartl, Markus, Schleper, Christa
Publicado 2023

Structural basis of IL-23 antagonism by an Alphabody protein scaffold

por Desmet, Johan, Verstraete, Kenneth, Bloch, Yehudi, Lorent, Eric, Wen, Yurong, Devreese, Bart, Vandenbroucke, Karen, Loverix, Stefan, Hettmann, Thore, Deroo, Sabrina, Somers, Klaartje, Henderikx, Paula, Lasters, Ignace, Savvides, Savvas N.
Publicado 2014

Attenuated CSF‐1R signalling drives cerebrovascular pathology

por Delaney, Conor, Farrell, Michael, Doherty, Colin P, Brennan, Kiva, O’Keeffe, Eoin, Greene, Chris, Byrne, Kieva, Kelly, Eoin, Birmingham, Niamh, Hickey, Paula, Cronin, Simon, Savvides, Savvas N, Doyle, Sarah L, Campbell, Matthew
Publicado 2020

Improving de novo protein binder design with deep learning

por Bennett, Nathaniel R., Coventry, Brian, Goreshnik, Inna, Huang, Buwei, Allen, Aza, Vafeados, Dionne, Peng, Ying Po, Dauparas, Justas, Baek, Minkyung, Stewart, Lance, DiMaio, Frank, De Munck, Steven, Savvides, Savvas N., Baker, David
Publicado 2023

Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

por Verstraete, Kenneth, Peelman, Frank, Braun, Harald, Lopez, Juan, Van Rompaey, Dries, Dansercoer, Ann, Vandenberghe, Isabel, Pauwels, Kris, Tavernier, Jan, Lambrecht, Bart N., Hammad, Hamida, De Winter, Hans, Beyaert, Rudi, Lippens, Guy, Savvides, Savvas N.
Publicado 2017

Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha

por Govindarajan, Srinath, Gaublomme, Djoere, Van der Cruyssen, Renée, Verheugen, Eveline, Van Gassen, Sofie, Saeys, Yvan, Tavernier, Simon, Iwawaki, Takao, Bloch, Yehudi, Savvides, Savvas. N., Lambrecht, Bart N., Janssens, Sophie, Elewaut, Dirk, Drennan, Michael B.
Publicado 2018

Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF

por Felix, Jan, Kandiah, Eaazhisai, De Munck, Steven, Bloch, Yehudi, van Zundert, Gydo C.P., Pauwels, Kris, Dansercoer, Ann, Novanska, Katka, Read, Randy J., Bonvin, Alexandre M.J.J., Vergauwen, Bjorn, Verstraete, Kenneth, Gutsche, Irina, Savvides, Savvas N.
Publicado 2016