The complex genetics of multiple sclerosis: pitfalls and prospects

por Sawcer, Stephen
Publicado 2008

The genetic aspects of multiple sclerosis

por Sawcer, Stephen
Publicado 2009

Comment on: Month of birth and risk of multiple sclerosis: confounding and adjustments

por Fiddes, Barnaby, Wason, James, Sawcer, Stephen
Publicado 2014

Confounding in association studies: month of birth and multiple sclerosis

por Fiddes, Barnaby, Wason, James, Sawcer, Stephen
Publicado 2014

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?: A Genetic Study

por Brown, Robin B., Traylor, Matthew, Burgess, Stephen, Sawcer, Stephen, Markus, Hugh S.
Publicado 2019

Confounding Underlies the Apparent Month of Birth Effect in Multiple Sclerosis

por Fiddes, Barnaby, Wason, James, Kemppinen, Anu, Ban, Maria, Compston, Alastair, Sawcer, Stephen
Publicado 2013

Investigation of the Role of Mitochondrial DNA in Multiple Sclerosis Susceptibility

por Ban, Maria, Elson, Joanna, Walton, Amie, Turnbull, Douglas, Compston, Alastair, Chinnery, Patrick, Sawcer, Stephen
Publicado 2008

Obesity and Multiple Sclerosis: A Mendelian Randomization Study

por Mokry, Lauren E., Ross, Stephanie, Timpson, Nicholas J., Sawcer, Stephen, Davey Smith, George, Richards, J. Brent
Publicado 2016

Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis

por Davies, Jessica L., Thompson, Sara, Kaur-Sandhu, Harpreet, Sawcer, Stephen, Coles, Alasdair, Ban, Maria, Jones, Joanne
Publicado 2016

Mononeuritis multiplex: an unexpectedly frequent feature of severe COVID-19

por Needham, Edward, Newcombe, Virginia, Michell, Andrew, Thornton, Rachel, Grainger, Andrew, Anwar, Fahim, Warburton, Elizabeth, Menon, David, Trivedi, Monica, Sawcer, Stephen
Publicado 2020

Age Related Multiple Sclerosis Severity Score: Disability ranked by age

por Manouchehrinia, Ali, Westerlind, Helga, Kingwell, Elaine, Zhu, Feng, Carruthers, Robert, Ramanujam, Ryan, Ban, Maria, Glaser, Anna, Sawcer, Stephen, Tremlett, Helen, Hillert, Jan
Publicado 2017

The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination

por Pu, Annie, Mishra, Manoj K., Dong, Yifei, Ghorbanigazar, Samira, Stephenson, Erin L., Rawji, Khalil S., Silva, Claudia, Kitagawa, Hiroshi, Sawcer, Stephen, Yong, V. Wee
Publicado 2020

Exploring rare and low-frequency variants in the Saguenay–Lac-Saint-Jean population identified genes associated with asthma and allergy traits

por Morin, Andréanne, Madore, Anne-Marie, Kwan, Tony, Ban, Maria, Partanen, Jukka, Rönnblom, Lars, Syvänen, Ann-Christine, Sawcer, Stephen, Stunnenberg, Hendrik, Lathrop, Mark, Pastinen, Tomi, Laprise, Catherine
Publicado 2018

Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

por Fortune, Mary D., Guo, Hui, Burren, Oliver, Schofield, Ellen, Walker, Neil M., Ban, Maria, Sawcer, Stephen J., Bowes, John, Worthington, Jane, Barton, Ann, Eyre, Steve, Todd, John A., Wallace, Chris
Publicado 2015

Imputation of KIR Types from SNP Variation Data

por Vukcevic, Damjan, Traherne, James A., Næss, Sigrid, Ellinghaus, Eva, Kamatani, Yoichiro, Dilthey, Alexander, Lathrop, Mark, Karlsen, Tom H., Franke, Andre, Moffatt, Miriam, Cookson, William, Trowsdale, John, McVean, Gil, Sawcer, Stephen, Leslie, Stephen
Publicado 2015

Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells

por Smets, Ide, Fiddes, Barnaby, Garcia-Perez, Josselyn E, He, Di, Mallants, Klara, Liao, Wenjia, Dooley, James, Wang, George, Humblet-Baron, Stephanie, Dubois, Bénédicte, Compston, Alastair, Jones, Joanne, Coles, Alasdair, Liston, Adrian, Ban, Maria, Goris, An, Sawcer, Stephen
Publicado 2018

Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells

por Morin, Andréanne, Kwan, Tony, Ge, Bing, Letourneau, Louis, Ban, Maria, Tandre, Karolina, Caron, Maxime, Sandling, Johanna K., Carlsson, Jonas, Bourque, Guillaume, Laprise, Catherine, Montpetit, Alexandre, Syvanen, Ann-Christine, Ronnblom, Lars, Sawcer, Stephen J., Lathrop, Mark G., Pastinen, Tomi
Publicado 2016

Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci

por Lemire, Mathieu, Zaidi, Syed H.E., Ban, Maria, Ge, Bing, Aïssi, Dylan, Germain, Marine, Kassam, Irfahan, Wang, Mike, Zanke, Brent W., Gagnon, France, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Wells, Philip S., Sawcer, Stephen, Gallinger, Steven, Pastinen, Tomi, Hudson, Thomas J.
Publicado 2015

IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

por Maier, Lisa M., Lowe, Christopher E., Cooper, Jason, Downes, Kate, Anderson, David E., Severson, Christopher, Clark, Pamela M., Healy, Brian, Walker, Neil, Aubin, Cristin, Oksenberg, Jorge R., Hauser, Stephen L., Compston, Alistair, Sawcer, Stephen, De Jager, Philip L., Wicker, Linda S., Todd, John A., Hafler, David A.
Publicado 2009

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

por Wallace, Chris, Cutler, Antony J, Pontikos, Nikolas, Pekalski, Marcin L, Burren, Oliver S, Cooper, Jason D, García, Arcadio Rubio, Ferreira, Ricardo C, Guo, Hui, Walker, Neil M, Smyth, Deborah J, Rich, Stephen S, Onengut-Gumuscu, Suna, Sawcer, Stephen J, Ban, Maria, Richardson, Sylvia, Todd, John A, Wicker, Linda S
Publicado 2015