Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal

por Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Ise, Wataru, Kawakami, Eiryo, Sax, Nicolas, Oki, Toshihiko, Kitamura, Toshio, Yamashita, Kazuo, Fukuyama, Hidehiro, Kurosaki, Tomohiro
Publicado 2020

Distinct immune cell dynamics correlate with the immunogenicity and reactogenicity of SARS-CoV-2 mRNA vaccine

por Takano, Tomohiro, Morikawa, Miwa, Adachi, Yu, Kabasawa, Kiyomi, Sax, Nicolas, Moriyama, Saya, Sun, Lin, Isogawa, Masanori, Nishiyama, Ayae, Onodera, Taishi, Terahara, Kazutaka, Tonouchi, Keisuke, Nishimura, Masashi, Tomii, Kentaro, Yamashita, Kazuo, Matsumura, Takayuki, Shinkai, Masaharu, Takahashi, Yoshimasa
Publicado 2022

Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses

por Shinnakasu, Ryo, Sakakibara, Shuhei, Yamamoto, Hiromi, Wang, Po-hung, Moriyama, Saya, Sax, Nicolas, Ono, Chikako, Yamanaka, Atsushi, Adachi, Yu, Onodera, Taishi, Sato, Takashi, Shinkai, Masaharu, Suzuki, Ryosuke, Matsuura, Yoshiharu, Hashii, Noritaka, Takahashi, Yoshimasa, Inoue, Takeshi, Yamashita, Kazuo, Kurosaki, Tomohiro
Publicado 2021

CD62L expression marks SARS-CoV-2 memory B cell subset with preference for neutralizing epitopes

por Onodera, Taishi, Sax, Nicolas, Sato, Takashi, Adachi, Yu, Kotaki, Ryutaro, Inoue, Takeshi, Shinnakasu, Ryo, Nakagawa, Takayuki, Fukushi, Shuetsu, Terooatea, Tommy, Yoshikawa, Mai, Tonouchi, Keisuke, Nagakura, Takaki, Moriyama, Saya, Matsumura, Takayuki, Isogawa, Masanori, Terahara, Kazutaka, Takano, Tomohiro, Sun, Lin, Nishiyama, Ayae, Omoto, Shinnya, Shinkai, Masaharu, Kurosaki, Tomohiro, Yamashita, Kazuo, Takahashi, Yoshimasa
Publicado 2023

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients

por Lu, Xiuyuan, Hosono, Yuki, Nagae, Masamichi, Ishizuka, Shigenari, Ishikawa, Eri, Motooka, Daisuke, Ozaki, Yuki, Sax, Nicolas, Maeda, Yuichi, Kato, Yasuhiro, Morita, Takayoshi, Shinnakasu, Ryo, Inoue, Takeshi, Onodera, Taishi, Matsumura, Takayuki, Shinkai, Masaharu, Sato, Takashi, Nakamura, Shota, Mori, Shunsuke, Kanda, Teru, Nakayama, Emi E., Shioda, Tatsuo, Kurosaki, Tomohiro, Takeda, Kiyoshi, Kumanogoh, Atsushi, Arase, Hisashi, Nakagami, Hironori, Yamashita, Kazuo, Takahashi, Yoshimasa, Yamasaki, Sho
Publicado 2021

Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration

por Morinaga, Takao, Inozume, Takashi, Kawazu, Masahito, Ueda, Youki, Sax, Nicolas, Yamashita, Kazuo, Kawashima, Shusuke, Nagasaki, Joji, Ueno, Toshihide, Lin, Jason, Ohara, Yuuki, Kuwata, Takeshi, Yukami, Hiroki, Kawazoe, Akihito, Shitara, Kohei, Honobe-Tabuchi, Akiko, Ohnuma, Takehiro, Kawamura, Tatsuyoshi, Umeda, Yoshiyasu, Kawahara, Yu, Nakamura, Yasuhiro, Kiniwa, Yukiko, Morita, Ayako, Ichihara, Eiki, Kiura, Katsuyuki, Enokida, Tomohiro, Tahara, Makoto, Hasegawa, Yoshinori, Mano, Hiroyuki, Suzuki, Yutaka, Nishikawa, Hiroyoshi, Togashi, Yosuke
Publicado 2022

Tumor-derived semaphorin 4A improves PD-1–blocking antibody efficacy by enhancing CD8(+) T cell cytotoxicity and proliferation

por Naito, Yujiro, Koyama, Shohei, Masuhiro, Kentaro, Hirai, Takashi, Uenami, Takeshi, Inoue, Takako, Osa, Akio, Machiyama, Hirotomo, Watanabe, Go, Sax, Nicolas, Villa, Jordan, Kinugasa-Katayama, Yumi, Nojima, Satoshi, Yaga, Moto, Hosono, Yuki, Okuzaki, Daisuke, Satoh, Shingo, Tsuda, Takeshi, Nakanishi, Yoshimitsu, Suga, Yasuhiko, Morita, Takayoshi, Fukushima, Kiyoharu, Nishide, Masayuki, Shiroyama, Takayuki, Miyake, Kotaro, Iwahori, Kota, Hirata, Haruhiko, Nagatomo, Izumi, Yano, Yukihiro, Tamiya, Motohiro, Kumagai, Toru, Takemoto, Norihiko, Inohara, Hidenori, Yamasaki, Sho, Yamashita, Kazuo, Aoshi, Taiki, Akbay, Esra A., Hosen, Naoki, Shintani, Yasushi, Takamatsu, Hyota, Mori, Masahide, Takeda, Yoshito, Kumanogoh, Atsushi
Publicado 2023