Cellular Redox Homeostasis

por Le Gal, Kristell, Schmidt, Edward E., Sayin, Volkan I.
Publicado 2021

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

por Ashouri, Arghavan, Sayin, Volkan I., Van den Eynden, Jimmy, Singh, Simranjit X., Papagiannakopoulos, Thales, Larsson, Erik
Publicado 2016

Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

por Le Gal, Kristell, Wiel, Clotilde, Ibrahim, Mohamed X., Henricsson, Marcus, Sayin, Volkan I., Bergo, Martin O.
Publicado 2021

KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer

por Eklund, Ella A., Wiel, Clotilde, Fagman, Henrik, Akyürek, Levent M., Raghavan, Sukanya, Nyman, Jan, Hallqvist, Andreas, Sayin, Volkan I.
Publicado 2022

Zinc Finger Protein 148 Is Dispensable for Primitive and Definitive Hematopoiesis in Mice

por Nilton, Anna, Sayin, Volkan I., Staffas, Anna, Larsson, Erik, Rolf, Julia, Petit, Marleen M., Palmqvist, Lars, Swolin, Birgitta, Cardell, Susanna, Lindahl, Per
Publicado 2013

Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice

por Petersen, Dennis R., Saba, Laura M., Sayin, Volkan I., Papagiannakopoulos, Thales, Schmidt, Edward E., Merrill, Gary F., Orlicky, David J., Shearn, Colin T.
Publicado 2018

Targeting Zfp148 activates p53 and reduces tumor initiation in the gut

por Nilton, Anna, Sayin, Volkan I., Zou, Zhiyuan V., Sayin, Sama I., Bondjers, Cecilia, Gul, Nadia, Agren, Pia, Fogelstrand, Per, Nilsson, Ola, Bergo, Martin O., Lindahl, Per
Publicado 2016

Combinatory analysis of immune cell subsets and tumor-specific genetic variants predict clinical response to PD-1 blockade in patients with non-small cell lung cancer

por Dutta, Nikita, Rohlin, Anna, Eklund, Ella A., Magnusson, Maria K., Nilsson, Frida, Akyürek, Levent M., Torstensson, Per, Sayin, Volkan I., Lundgren, Anna, Hallqvist, Andreas, Raghavan, Sukanya
Publicado 2023

Zfp148 Deficiency Causes Lung Maturation Defects and Lethality in Newborn Mice That Are Rescued by Deletion of p53 or Antioxidant Treatment

por Sayin, Volkan I., Nilton, Anna, Ibrahim, Mohamed X., Ågren, Pia, Larsson, Erik, Petit, Marleen M., Hultén, Lillemor Mattsson, Ståhlman, Marcus, Johansson, Bengt R., Bergo, Martin O., Lindahl, Per
Publicado 2013

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

por Akula, Murali K., Ibrahim, Mohamed X., Ivarsson, Emil G., Khan, Omar M., Kumar, Israiel T., Erlandsson, Malin, Karlsson, Christin, Xu, Xiufeng, Brisslert, Mikael, Brakebusch, Cord, Wang, Donghai, Bokarewa, Maria, Sayin, Volkan I., Bergo, Martin O.
Publicado 2019

Antioxidants Promote Intestinal Tumor Progression in Mice

por Zou, Zhiyuan V., Le Gal, Kristell, El Zowalaty, Ahmed E., Pehlivanoglu, Lara E., Garellick, Viktor, Gul, Nadia, Ibrahim, Mohamed X., Bergh, Per-Olof, Henricsson, Marcus, Wiel, Clotilde, Akyürek, Levent M., Bergo, Martin O., Sayin, Volkan I., Lindahl, Per
Publicado 2021

The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity

por Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano
Publicado 2022

Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway

por Zou, Zhiyuan V., Gul, Nadia, Lindberg, Markus, Bokhari, Abdulmalik A., Eklund, Ella M., Garellick, Viktor, Patel, Angana A. H., Dzanan, Jozefina J., Titmuss, Ben O., Le Gal, Kristell, Johansson, Inger, Tivesten, Åsa, Forssell-Aronsson, Eva, Bergö, Martin O., Staffas, Anna, Larsson, Erik, Sayin, Volkan I., Lindahl, Per
Publicado 2020

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

por Sayin, Volkan I, LeBoeuf, Sarah E, Singh, Simranjit X, Davidson, Shawn M, Biancur, Douglas, Guzelhan, Betul S, Alvarez, Samantha W, Wu, Warren L, Karakousi, Triantafyllia R, Zavitsanou, Anastasia Maria, Ubriaco, Julian, Muir, Alexander, Karagiannis, Dimitris, Morris, Patrick J, Thomas, Craig J, Possemato, Richard, Vander Heiden, Matthew G, Papagiannakopoulos, Thales
Publicado 2017

Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P

por Schwarz, Maria, Meyer, Caroline E., Löser, Alina, Lossow, Kristina, Hackler, Julian, Ott, Christiane, Jäger, Susanne, Mohr, Isabelle, Eklund, Ella A., Patel, Angana A. H., Gul, Nadia, Alvarez, Samantha, Altinonder, Ilayda, Wiel, Clotilde, Maares, Maria, Haase, Hajo, Härtlova, Anetta, Grune, Tilman, Schulze, Matthias B., Schwerdtle, Tanja, Merle, Uta, Zischka, Hans, Sayin, Volkan I., Schomburg, Lutz, Kipp, Anna P.
Publicado 2023

Keap1 loss promotes Kras-driven lung cancer and results in a dependence on glutaminolysis

por Romero, Rodrigo, Sayin, Volkan I., Davidson, Shawn M., Bauer, Matthew R., Singh, Simranjit X., LeBoeuf, Sarah E., Karakousi, Triantafyllia R., Ellis, Donald C., Bhutkar, Arjun, Sanchez-Rivera, Francisco J., Subbaraj, Lakshmipriya, Martinez, Britney, Bronson, Roderick T., Prigge, Justin R., Schmidt, Edward E., Thomas, Craig J., Goparaju, Chandra, Davies, Angela, Dolgalev, Igor, Heguy, Adriana, Allaj, Viola, Poirier, John T., Moreira, Andre L., Rudin, Charles M., Pass, Harvey I., Vander Heiden, Matthew G., Jacks, Tyler, Papagiannakopoulos, Thales
Publicado 2017