In vitro generation of human cells with cancer stem cell properties

por Scaffidi, Paola, Misteli, Tom
Publicado 2011

Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity

por Wainwright, Elanor N., Scaffidi, Paola
Publicado 2017

The Cell Nucleus and Aging: Tantalizing Clues and Hopeful Promises

por Scaffidi, Paola, Gordon, Leslie, Misteli, Tom
Publicado 2005

Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to in vivo assays

por Henser-Brownhill, Tristan, Monserrat, Josep, Scaffidi, Paola
Publicado 2018

CRISPR-based large-scale modeling of loss-of-function mutations to investigate mechanisms of stress resistance in cancer

por Simeoni, Fabrizio, Loukas, Ioannis, Wilson, Thomas Stuart, Scaffidi, Paola
Publicado 2023

Genome-wide redistribution of BRD4 binding sites in transformation resistant cells

por Si, Han, Scaffidi, Paola, Merchant, Anand, Cam, Maggie, Stahlberg, Eric, Misteli, Tom, Fernandez, Patricia
Publicado 2014

Target-Specific Precision of CRISPR-Mediated Genome Editing

por Chakrabarti, Anob M., Henser-Brownhill, Tristan, Monserrat, Josep, Poetsch, Anna R., Luscombe, Nicholas M., Scaffidi, Paola
Publicado 2019

Redistribution of EZH2 promotes malignant phenotypes by rewiring developmental programmes

por Mortimer, Thomas, Wainwright, Elanor N, Patel, Harshil, Siow, Bernard M, Jaunmuktane, Zane, Brandner, Sebastian, Scaffidi, Paola
Publicado 2019

The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells

por Degryse, Bernard, Bonaldi, Tiziana, Scaffidi, Paola, Müller, Susanne, Resnati, Massimo, Sanvito, Francesca, Arrigoni, Gianluigi, Bianchi, Marco E.
Publicado 2001

Label-Free Mass Spectrometry-Based Quantification of Linker Histone H1 Variants in Clinical Samples

por Noberini, Roberta, Morales Torres, Cristina, Savoia, Evelyn Oliva, Brandini, Stefania, Jodice, Maria Giovanna, Bertalot, Giovanni, Bonizzi, Giuseppina, Capra, Maria, Diaferia, Giuseppe, Scaffidi, Paola, Bonaldi, Tiziana
Publicado 2020

H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function

por Pal, Debosree, Patel, Manthan, Boulet, Fanny, Sundarraj, Jayakumar, Grant, Olivia A., Branco, Miguel R., Basu, Srinjan, Santos, Silvia D. M., Zabet, Nicolae Radu, Scaffidi, Paola, Pradeepa, Madapura M.
Publicado 2023

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

por Mourikis, Thanos P., Benedetti, Lorena, Foxall, Elizabeth, Temelkovski, Damjan, Nulsen, Joel, Perner, Juliane, Cereda, Matteo, Lagergren, Jesper, Howell, Michael, Yau, Christopher, Fitzgerald, Rebecca C., Scaffidi, Paola, Ciccarelli, Francesca D.
Publicado 2019

Disruption of the MSL complex inhibits tumor maintenance by exacerbating chromosomal instability

por Monserrat, Josep, Torres, Cristina Morales, Richardson, Louise, Wilson, Thomas S., Patel, Harshil, Domart, Marie-Charlotte, Horswell, Stuart, Song, Ok-Ryul, Jiang, Ming, Crawford, Margaret, Bui, Minh, Dalal, Yamini, Scaffidi, Paola
Publicado 2021

Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis

por Morales Torres, Cristina, Wu, Mary Y., Hobor, Sebastijan, Wainwright, Elanor N., Martin, Matthew J., Patel, Harshil, Grey, William, Grönroos, Eva, Howell, Steven, Carvalho, Joana, Snijders, Ambrosius P., Bustin, Michael, Bonnet, Dominique, Smith, Paul D., Swanton, Charles, Howell, Michael, Scaffidi, Paola
Publicado 2020

ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer

por Moreno, Thaidy, Monterde, Beatriz, González-Silva, Laura, Betancor-Fernández, Isabel, Revilla, Carlos, Agraz-Doblas, Antonio, Freire, Javier, Isidro, Pablo, Quevedo, Laura, Blanco, Rosa, Montes-Moreno, Santiago, Cereceda, Laura, Astudillo, Aurora, Casar, Berta, Crespo, Piero, Torres, Cristina Morales, Scaffidi, Paola, Gomez-Roman, Javier, Salido, Eduardo, Varela, Ignacio
Publicado 2021