Analysis of gene repair tracts from Cas9/gRNA double-stranded breaks in the human CFTR gene

por Hollywood, Jennifer A., Lee, Ciaran M., Scallan, Martina F., Harrison, Patrick T.
Publicado 2016

Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA

por Sanz, David J., Hollywood, Jennifer A., Scallan, Martina F., Harrison, Patrick T.
Publicado 2017

Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair

por Lee, Ciaran M., Flynn, Rowan, Hollywood, Jennifer A., Scallan, Martina F., Harrison, Patrick T.
Publicado 2012

AAV2-mediated in vivo immune gene therapy of solid tumours

por Collins, Sara A, Buhles, Alexandra, Scallan, Martina F, Harrison, Patrick T, O'Hanlon, Deirdre M, O'Sullivan, Gerald C, Tangney, Mark
Publicado 2010

Developing student codesigned immersive virtual reality simulations for teaching of challenging concepts in molecular and cellular biology

por Reen, F Jerry, Jump, Owen, McEvoy, Grace, McSharry, Brian P, Morgan, John, Murphy, David, O'Leary, Niall, O'Mahony, Billy, Scallan, Martina, Walsh, Christine, Supple, Briony
Publicado 2022

Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X

por Mention, Karen, Cavusoglu-Doran, Kader, Joynt, Anya T, Santos, Lúcia, Sanz, David, Eastman, Alice C, Merlo, Christian, Langfelder-Schwind, Elinor, Scallan, Martina F, Farinha, Carlos M, Cutting, Garry R, Sharma, Neeraj, Harrison, Patrick T
Publicado 2023