TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis

por Bafica, Andre, Scanga, Charles A., Feng, Carl G., Leifer, Cynthia, Cheever, Allen, Sher, Alan
Publicado 2005

Depletion of Cd4(+) T Cells Causes Reactivation of Murine Persistent Tuberculosis despite Continued Expression of Interferon γ and Nitric Oxide Synthase 2

por Scanga, Charles A., Mohan, V.P., Yu, Keming, Joseph, Heather, Tanaka, Kathryn, Chan, John, Flynn, JoAnne L.
Publicado 2000

Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas

por Grant, Nicole L., Kelly, Kristen, Maiello, Pauline, Abbott, Helena, O’Connor, Shelby, Lin, Philana Ling, Scanga, Charles A., Flynn, JoAnne L.
Publicado 2023

MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection

por Ellis, Amy L., Balgeman, Alexis J., Larson, Erica C., Rodgers, Mark A., Ameel, Cassaundra, Baranowski, Tonilynn, Kannal, Nadean, Maiello, Pauline, Juno, Jennifer A., Scanga, Charles A., O’Connor, Shelby L.
Publicado 2020

Antibody glycosylation correlates with disease progression in SIV‐ Mycobacterium tuberculosis coinfected cynomolgus macaques

por Haycroft, Ebene R, Damelang, Timon, Lopez, Ester, Rodgers, Mark A, Wines, Bruce D, Hogarth, Mark, Ameel, Cassaundra L, Kent, Stephen J, Scanga, Charles A, O'Connor, Shelby L, Chung, Amy W
Publicado 2023

Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis

por Moriarty, Ryan V., Rodgers, Mark A., Ellis, Amy L., Balgeman, Alexis J., Larson, Erica C., Hopkins, Forrest, Chase, Michael R., Maiello, Pauline, Fortune, Sarah M., Scanga, Charles A., O’Connor, Shelby L.
Publicado 2022

rBCG Induces Strong Antigen-Specific T Cell Responses in Rhesus Macaques in a Prime-Boost Setting with an Adenovirus 35 Tuberculosis Vaccine Vector

por Magalhaes, Isabelle, Sizemore, Donata R., Ahmed, Raija K., Mueller, Stefanie, Wehlin, Lena, Scanga, Charles, Weichold, Frank, Schirru, Giulia, Pau, Maria Grazia, Goudsmit, Jaap, Kühlmann-Berenzon, Sharon, Spångberg, Mats, Andersson, Jan, Gaines, Hans, Thorstensson, Rigmor, Skeiky, Yasir A. W., Sadoff, Jerry, Maeurer, Markus
Publicado 2008

Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes

por Rockwood, Neesha, Costa, Diego L., Amaral, Eduardo P., Du Bruyn, Elsa, Kubler, Andre, Gil-Santana, Leonardo, Fukutani, Kiyoshi F., Scanga, Charles A., Flynn, JoAnne L., Jackson, Sharon H., Wilkinson, Katalin A., Bishai, William R., Sher, Alan, Wilkinson, Robert J., Andrade, Bruno B.
Publicado 2017

Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens

por Budak, Maral, Cicchese, Joseph M., Maiello, Pauline, Borish, H. Jacob, White, Alexander G., Chishti, Harris B., Tomko, Jaime, Frye, L. James, Fillmore, Daniel, Kracinovsky, Kara, Sakal, Jennifer, Scanga, Charles A., Lin, Philana Ling, Dartois, Véronique, Linderman, Jennifer J., Flynn, JoAnne L., Kirschner, Denise E.
Publicado 2023

Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques

por Darrah, Patricia A., DiFazio, Robert M., Maiello, Pauline, Gideon, Hannah P., Myers, Amy J., Rodgers, Mark A., Hackney, Joshua A., Lindenstrom, Thomas, Evans, Thomas, Scanga, Charles A., Prikhodko, Victor, Andersen, Peter, Lin, Philana Ling, Laddy, Dominick, Roederer, Mario, Seder, Robert A., Flynn, JoAnne L.
Publicado 2019

Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates

por Stammes, Marieke A., Lee, Ji Hyun, Meijer, Lisette, Naninck, Thibaut, Doyle-Meyers, Lara A., White, Alexander G., Borish, H. Jacob, Hartman, Amy L., Alvarez, Xavier, Ganatra, Shashank, Kaushal, Deepak, Bohm, Rudolf P., le Grand, Roger, Scanga, Charles A., Langermans, Jan A.M., Bontrop, Ronald E., Finch, Courtney L., Flynn, JoAnne L., Calcagno, Claudia, Crozier, Ian, Kuhn, Jens H.
Publicado 2022

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques

por Larson, Erica C., Ellis, Amy L., Rodgers, Mark A., Gubernat, Abigail K., Gleim, Janelle L., Moriarty, Ryan V., Balgeman, Alexis J., Menezes, Yonne K., Ameel, Cassaundra L., Fillmore, Daniel J., Pergalske, Skyler M., Juno, Jennifer A., Maiello, Pauline, White, Alexander G., Borish, H. Jacob, Godfrey, Dale I., Kent, Stephen J., Ndhlovu, Lishomwa C., O’Connor, Shelby L., Scanga, Charles A.
Publicado 2023

Prevention of tuberculosis in macaques after intravenous BCG immunization

por Darrah, Patricia A., Zeppa, Joseph J., Maiello, Pauline, Hackney, Joshua A., Wadsworth, Marc H., Hughes, Travis K., Pokkali, Supriya, Swanson, Phillip A., Grant, Nicole L., Rodgers, Mark A., Kamath, Megha, Causgrove, Chelsea M., Laddy, Dominick J., Bonavia, Aurelio, Casimiro, Danilo, Lin, Philana Ling, Klein, Edwin, White, Alexander G., Scanga, Charles A., Shalek, Alex K., Roederer, Mario, Flynn, JoAnne L., Seder, Robert A.
Publicado 2020

Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis

por Larson, Erica C., Ellis-Connell, Amy L., Rodgers, Mark A., Gubernat, Abigail K., Gleim, Janelle L., Moriarty, Ryan V., Balgeman, Alexis J., Ameel, Cassaundra L., Jauro, Solomon, Tomko, Jaime A., Kracinovsky, Kara B., Maiello, Pauline, Borish, H. Jake, White, Alexander G., Klein, Edwin, Bucsan, Allison N., Darrah, Patricia A., Seder, Robert A., Roederer, Mario, Lin, Philana Ling, Flynn, JoAnne L., O’Connor, Shelby L., Scanga, Charles A.
Publicado 2023

Intravenous Bacille Calmette–Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis

por Larson, Erica C., Ellis-Connell, Amy L., Rodgers, Mark A., Gubernat, Abigail K., Gleim, Janelle L., Moriarty, Ryan V., Balgeman, Alexis J., Ameel, Cassaundra L., Jauro, Solomon, Tomko, Jaime A., Kracinovsky, Kara B., Maiello, Pauline, Borish, H. Jake, White, Alexander G., Klein, Edwin, Bucsan, Allison N., Darrah, Patricia A., Seder, Robert A., Roederer, Mario, Lin, Philana Ling, Flynn, JoAnne L., O’Connor, Shelby L., Scanga, Charles A.
Publicado 2023

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastroint...

por Hartman, Amy L., Nambulli, Sham, McMillen, Cynthia M., White, Alexander G., Tilston-Lunel, Natasha Louise, Albe, Joseph R., Cottle, Emily, Dunn, Matthew D., Frye, L. James, Gilliland, Theron H., Olsen, Emily L., O’Malley, Katherine J., Schwarz, Madeline M., Tomko, Jaime A., Walker, Reagan C., Xia, Mengying, Hartman, Matthew S., Klein, Edwin, Scanga, Charles A., Flynn, JoAnne L., Klimstra, William B., McElroy, Anita K., Reed, Douglas S., Duprex, W. Paul
Publicado 2020

Distributable, Metabolic PET Reporting of Tuberculosis

por Naseer Khan, R.M., Ahn, Yong-Mo, Marriner, Gwendolyn A., Via, Laura E., D’Hooge, Francois, Lee, Seung Seo, Yang, Nan, Basuli, Falguni, White, Alexander G., Tomko, Jaime A., Frye, L. James, Scanga, Charles A., Weiner, Danielle M., Sutphen, Michelle L., Schimel, Daniel M., Dayao, Emmanuel, Piazza, Michaela K., Gomez, Felipe, Dieckmann, William, Herscovitch, Peter, Mason, N. Scott, Swenson, Rolf, Kiesewetter, Dale O., Backus, Keriann M., Geng, Yiqun, Raj, Ritu, Anthony, Daniel C., Flynn, JoAnne L., Barry, Clifton E., Davis, Benjamin G.
Publicado 2023

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

por Gideon, Hannah P., Hughes, Travis K., Tzouanas, Constantine N., Wadsworth, Marc H., Tu, Ang Andy, Gierahn, Todd M., Peters, Joshua M., Hopkins, Forrest F., Wei, Jun-Rong, Kummerlowe, Conner, Grant, Nicole L., Nargan, Kievershen, Phuah, Jia Yao, Borish, H. Jacob, Maiello, Pauline, White, Alexander G., Winchell, Caylin G., Nyquist, Sarah K., Ganchua, Sharie Keanne C., Myers, Amy, Patel, Kush V., Ameel, Cassaundra L., Cochran, Catherine T., Ibrahim, Samira, Tomko, Jaime A., Frye, Lonnie James, Rosenberg, Jacob M., Shih, Angela, Chao, Michael, Klein, Edwin, Scanga, Charles A., Ordovas-Montanes, Jose, Berger, Bonnie, Mattila, Joshua T., Madansein, Rajhmun, Love, J. Christopher, Lin, Philana Ling, Leslie, Alasdair, Behar, Samuel M., Bryson, Bryan, Flynn, JoAnne L., Fortune, Sarah M., Shalek, Alex K.
Publicado 2022