Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine

por Greco, Rosaria, Demartini, Chiara, Zanaboni, Anna Maria, Francavilla, Miriam, Reggiani, Angelo, Realini, Natalia, Scarpelli, Rita, Piomelli, Daniele, Tassorelli, Cristina
Publicado 2022

Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

por Caputo, Samantha, Di Martino, Simona, Cilibrasi, Vincenzo, Tardia, Piero, Mazzonna, Marco, Russo, Debora, Penna, Ilaria, Summa, Maria, Bertozzi, Sine Mandrup, Realini, Natalia, Margaroli, Natasha, Migliore, Marco, Ottonello, Giuliana, Liu, Min, Lansbury, Peter, Armirotti, Andrea, Bertorelli, Rosalia, Ray, Soumya S., Skerlj, Renato, Scarpelli, Rita
Publicado 2020

Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors

por Di Martino, Simona, Tardia, Piero, Cilibrasi, Vincenzo, Caputo, Samantha, Mazzonna, Marco, Russo, Debora, Penna, Ilaria, Realini, Natalia, Margaroli, Natasha, Migliore, Marco, Pizzirani, Daniela, Ottonello, Giuliana, Bertozzi, Sine Mandrup, Armirotti, Andrea, Nguyen, Duc, Sun, Ying, Bongarzone, Ernesto R., Lansbury, Peter, Liu, Min, Skerlj, Renato, Scarpelli, Rita
Publicado 2020