Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments

por Jung, Yoo Jin, Tweedie, David, Scerba, Michael T., Greig, Nigel H.
Publicado 2019

Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders

por Jung, Yoo Jin, Tweedie, David, Scerba, Michael T., Kim, Dong Seok, Palmas, Maria Francesca, Pisanu, Augusta, Carta, Anna R., Greig, Nigel H.
Publicado 2021

Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6′-Dithiothalidomide on Traumatic Brain Injury

por Batsaikhan, Buyandelger, Wang, Jing-Ya, Scerba, Michael T., Tweedie, David, Greig, Nigel H., Miller, Jonathan P., Hoffer, Barry J., Lin, Chih-Tung, Wang, Jia-Yi
Publicado 2019

Activity of a Novel Anti-Inflammatory Agent F-3,6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury

por Hsueh, Shih Chang, Scerba, Michael T., Tweedie, David, Lecca, Daniela, Kim, Dong Seok, Baig, Abdul Mannan, Kim, Yu Kyung, Hwang, Inho, Kim, Sun, Selman, Warren R., Hoffer, Barry J., Greig, Nigel H.
Publicado 2022

3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation

por Lin, Chih-Tung, Lecca, Daniela, Yang, Ling-Yu, Luo, Weiming, Scerba, Michael T, Tweedie, David, Huang, Pen-Sen, Jung, Yoo-Jin, Kim, Dong Seok, Yang, Chih-Hao, Hoffer, Barry J, Wang, Jia-Yi, Greig, Nigel H
Publicado 2020

Pomalidomide Reduces Ischemic Brain Injury in Rodents

por Tsai, Yan-Rou, Tweedie, David, Navas-Enamorado, Ignacio, Scerba, Michael T., Chang, Cheng-Fu, Lai, Jing-Huei, Wu, John Chung-Che, Chen, Yen-Hua, Kang, Shuo-Jhen, Hoffer, Barry J., de Cabo, Rafael, Greig, Nigel H., Chiang, Yung-Hsiao, Chen, Kai-Yun
Publicado 2019

Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson’s Disease

por Palmas, Maria Francesca, Ena, Anna, Burgaletto, Chiara, Casu, Maria Antonietta, Cantarella, Giuseppina, Carboni, Ezio, Etzi, Michela, De Simone, Alfonso, Fusco, Giuliana, Cardia, Maria Cristina, Lai, Francesco, Picci, Luca, Tweedie, David, Scerba, Michael T., Coroneo, Valentina, Bernardini, Renato, Greig, Nigel H., Pisanu, Augusta, Carta, Anna R.
Publicado 2022

Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

por Lecca, Daniela, Jung, Yoo Jin, Scerba, Michael T., Hwang, Inho, Kim, Yu Kyung, Kim, Sun, Modrow, Sydney, Tweedie, David, Hsueh, Shih‐Chang, Liu, Dong, Luo, Weiming, Glotfelty, Elliot, Li, Yazhou, Wang, Jia‐Yi, Luo, Yu, Hoffer, Barry J., Kim, Dong Seok, McDevitt, Ross A., Greig, Nigel H.
Publicado 2022

3,6′- and 1,6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation

por Tsai, Yan-Rou, Kim, Dong Seok, Hsueh, Shih-Chang, Chen, Kai-Yun, Wu, John Chung-Che, Wang, Jia-Yi, Tsou, Yi-Syue, Hwang, Inho, Kim, Yukyung, Gil, Dayeon, Jo, Eui Jung, Han, Baek-Soo, Tweedie, David, Lecca, Daniela, Scerba, Michael T., Selman, Warren R., Hoffer, Barry J., Greig, Nigel H., Chiang, Yung-Hsiao
Publicado 2022