Cell-Based Small-Molecule Compound Screen Identifies Fenretinide as Potential Therapeutic for Translocation-Positive Rhabdomyosarcoma

por Herrero Martín, David, Boro, Aleksandar, Schäfer, Beat W.
Publicado 2013

ESF-EMBO Symposium “Molecular Biology and Innovative Therapies in Sarcomas of Childhood and Adolescence” Sept 29–Oct 4, Polonia Castle Pultusk, Poland

por Schäfer, Beat W., Koscielniak, Ewa, Kovar, Heinrich, Fulda, Simone
Publicado 2013

Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells

por Brack, Eva, Bender, Sabine, Wachtel, Marco, Pruschy, Martin, Schäfer, Beat W.
Publicado 2021

Furin Targeted Drug Delivery for Treatment of Rhabdomyosarcoma in a Mouse Model

por Hajdin, Katarina, D'Alessandro, Valentina, Niggli, Felix K., Schäfer, Beat W., Bernasconi, Michele
Publicado 2010

Dral Is a P53-Responsive Gene Whose Four and a Half Lim Domain Protein Product Induces Apoptosis

por Scholl, Florence A., McLoughlin, Patricia, Ehler, Elisabeth, de Giovanni, Carla, Schäfer, Beat W.
Publicado 2000

A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurre...

por Manzella, Gabriele, Moonamale, Devmini C., Römmele, Michaela, Bode, Peter, Wachtel, Marco, Schäfer, Beat W.
Publicado 2021

High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma

por Generali, Melanie, Satheesha, Sampoorna, Bode, Peter K., Wanner, Debora, Schäfer, Beat W., Casanova, Elisa A.
Publicado 2021

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion

por Jaaks, Patricia, D’Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W., Bernasconi, Michele
Publicado 2016

CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma

por Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.
Publicado 2022

Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma

por Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.
Publicado 2022

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1

por Giorgi, Chiara, Boro, Aleksandar, Rechfeld, Florian, Lopez-Garcia, Laura A., Gierisch, Maria E., Schäfer, Beat W., Niggli, Felix K.
Publicado 2015

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

por Jaaks, Patricia, Meier, Gianmarco, Alijaj, Nagjie, Brack, Eva, Bode, Peter, Koscielniak, Ewa, Wachtel, Marco, Schäfer, Beat W., Bernasconi, Michele
Publicado 2016

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

por Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.
Publicado 2019

Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization

por Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P., Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A., Niggli, Felix K., Schäfer, Beat W.
Publicado 2022

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

por Gatz, Susanne A., Aladowicz, Ewa, Casanova, Michela, Chisholm, Julia C., Kearns, Pamela R., Fulda, Simone, Geoerger, Birgit, Schäfer, Beat W., Shipley, Janet M.
Publicado 2019

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

por Hensel, Tim, Giorgi, Chiara, Schmidt, Oxana, Calzada-Wack, Julia, Neff, Frauke, Buch, Thorsten, Niggli, Felix K., Schäfer, Beat W., Burdach, Stefan, Richter, Günther H.S.
Publicado 2015

Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma

por Pomella, Silvia, Danielli, Sara G., Alaggio, Rita, Breunis, Willemijn B., Hamed, Ebrahem, Selfe, Joanna, Wachtel, Marco, Walters, Zoe S., Schäfer, Beat W., Rota, Rossella, Shipley, Janet M., Hettmer, Simone
Publicado 2023

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

por Alijaj, Nagjie, Moutel, Sandrine, Gouveia, Zelia L., Gray, Maxim, Roveri, Maurizio, Dzhumashev, Dzhangar, Weber, Florian, Meier, Gianmarco, Luciani, Paola, Rössler, Jochen K., Schäfer, Beat W., Perez, Franck, Bernasconi, Michele
Publicado 2020

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

por Marques, Joana G, Gryder, Berkley E, Pavlovic, Blaz, Chung, Yeonjoo, Ngo, Quy A, Frommelt, Fabian, Gstaiger, Matthias, Song, Young, Benischke, Katharina, Laubscher, Dominik, Wachtel, Marco, Khan, Javed, Schäfer, Beat W
Publicado 2020

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres

por Walter, Dagmar, Satheesha, Sampoorna, Albrecht, Patrick, Bornhauser, Beat C., D'Alessandro, Valentina, Oesch, Susanne M., Rehrauer, Hubert, Leuschner, Ivo, Koscielniak, Ewa, Gengler, Carole, Moch, Holger, Bernasconi, Michele, Niggli, Felix K., Schäfer, Beat W.
Publicado 2011