The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism

por Kögel, Alexander, Keidel, Achim, Bonneau, Fabien, Schäfer, Ingmar B., Conti, Elena
Publicado 2022

CENP‐C unwraps the human CENP‐A nucleosome through the H2A C‐terminal tail

por Ali‐Ahmad, Ahmad, Bilokapić, Silvija, Schäfer, Ingmar B, Halić, Mario, Sekulić, Nikolina
Publicado 2019

Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA–RNA interactions

por Bonneau, Fabien, Basquin, Jérôme, Steigenberger, Barbara, Schäfer, Tillman, Schäfer, Ingmar B., Conti, Elena
Publicado 2023

Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly

por Keidel, Achim, Kögel, Alexander, Reichelt, Peter, Kowalinski, Eva, Schäfer, Ingmar B., Conti, Elena
Publicado 2023

Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain

por Gutmann, Theresia, Schäfer, Ingmar B., Poojari, Chetan, Brankatschk, Beate, Vattulainen, Ilpo, Strauss, Mike, Coskun, Ünal
Publicado 2019

Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase

por Schäfer, Ingmar B., Yamashita, Masami, Schuller, Jan Michael, Schüssler, Steffen, Reichelt, Peter, Strauss, Mike, Conti, Elena
Publicado 2019

Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3

por Finogenova, Ksenia, Bonnet, Jacques, Poepsel, Simon, Schäfer, Ingmar B, Finkl, Katja, Schmid, Katharina, Litz, Claudia, Strauss, Mike, Benda, Christian, Müller, Jürg
Publicado 2020

Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

por Taschner, Michael, Basquin, Jérôme, Steigenberger, Barbara, Schäfer, Ingmar B, Soh, Young‐Min, Basquin, Claire, Lorentzen, Esben, Räschle, Markus, Scheltema, Richard A, Gruber, Stephan
Publicado 2021

Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

por Kent, Helen M., Evans, Philip R., Schäfer, Ingmar B., Gray, Sally R., Sanderson, Christopher M., Luzio, J. Paul, Peden, Andrew A., Owen, David J.
Publicado 2012

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

por Schäfer, Ingmar B., Hesketh, Geoffrey G., Bright, Nicholas A., Gray, Sally R., Pryor, Paul R., Evans, Philip R, Luzio, J. Paul, Owen, David J.
Publicado 2012

VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

por Hesketh, Geoffrey G., Pérez-Dorado, Inmaculada, Jackson, Lauren P., Wartosch, Lena, Schäfer, Ingmar B., Gray, Sally R., McCoy, Airlie J., Zeldin, Oliver B., Garman, Elspeth F., Harbour, Michael E., Evans, Philip R., Seaman, Matthew N.J., Luzio, J. Paul, Owen, David J.
Publicado 2014

Symmetric and Asymmetric Receptor Conformation Continuum induced by a Novel Insulin

por Xiong, Xiaochun, Blakely, Alan, Kim, Jin Hwan, Menting, John G., Schäfer, Ingmar B., Schubert, Heidi L., Agrawal, Rahul, Gutmann, Theresia, Delaine, Carlie, Zhang, Yi Wolf, Artik, Gizem Olay, Merriman, Allanah, Eckert, Debbie, Lawrence, Michael C., Coskun, Ünal, Fisher, Simon J., Forbes, Briony E., Safavi-Hemami, Helena, Hill, Christopher P., Chou, Danny Hung-Chieh
Publicado 2022