DNA glycosylases: in DNA repair and beyond

por Jacobs, Angelika L., Schär, Primo
Publicado 2011

Versatile Recombinant SUMOylation System for the Production of SUMO-Modified Protein

por Weber, Alain R., Schuermann, David, Schär, Primo
Publicado 2014

Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stability

por Krawczyk, Claudia, Dion, Vincent, Schär, Primo, Fritsch, Olivier
Publicado 2014

Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2

por Hardeland, Ulrike, Kunz, Christophe, Focke, Frauke, Szadkowski, Marta, Schär, Primo
Publicado 2007

Longitudinal analysis of healthy colon establishes aspirin as a suppressor of cancer-related epigenetic aging

por Noreen, Faiza, Chaber-Ciopinska, Anna, Regula, Jaroslaw, Schär, Primo, Truninger, Kaspar
Publicado 2020

7,8-dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases

por Talhaoui, Ibtissam, Couvé, Sophie, Ishchenko, Alexander A., Kunz, Christophe, Schär, Primo, Saparbaev, Murat
Publicado 2013

Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil

por Kunz, Christophe, Focke, Frauke, Saito, Yusuke, Schuermann, David, Lettieri, Teresa, Selfridge, Jim, Schär, Primo
Publicado 2009

3CAPS – a structural AP–site analogue as a tool to investigate DNA base excision repair

por Schuermann, David, Scheidegger, Simon P., Weber, Alain R., Bjørås, Magnar, Leumann, Christian J., Schär, Primo
Publicado 2016

Conserved interactions of the splicing factor Ntr1/Spp382 with proteins involved in DNA double-strand break repair and telomere metabolism

por Herrmann, Gernot, Kais, Sanja, Hoffbauer, Jan, Shah-Hosseini, Kijwasch, Brüggenolte, Nicole, Schober, Heiko, Fäsi, Margaret, Schär, Primo
Publicado 2007

Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers

por Wilson, Gareth A, Dhami, Pawandeep, Feber, Andrew, Cortázar, Daniel, Suzuki, Yuka, Schulz, Reiner, Schär, Primo, Beck, Stephan
Publicado 2012

Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle

por Noreen, Faiza, Röösli, Martin, Gaj, Pawel, Pietrzak, Jakub, Weis, Stefan, Urfer, Patric, Regula, Jaroslaw, Schär, Primo, Truninger, Kaspar
Publicado 2014

Oestrogen receptor β regulates epigenetic patterns at specific genomic loci through interaction with thymine DNA glycosylase

por Liu, Yun, Duong, William, Krawczyk, Claudia, Bretschneider, Nancy, Borbély, Gábor, Varshney, Mukesh, Zinser, Christian, Schär, Primo, Rüegg, Joëlle
Publicado 2016

Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism

por Weber, Alain R., Krawczyk, Claudia, Robertson, Adam B., Kuśnierczyk, Anna, Vågbø, Cathrine B., Schuermann, David, Klungland, Arne, Schär, Primo
Publicado 2016

ELF-MF exposure affects the robustness of epigenetic programming during granulopoiesis

por Manser, Melissa, Sater, Mohamad R. Abdul, Schmid, Christoph D., Noreen, Faiza, Murbach, Manuel, Kuster, Niels, Schuermann, David, Schär, Primo
Publicado 2017

Inducible TDG knockout models to study epigenetic regulation

por Schwarz, Simon D., Grundbacher, Eliane, Hrovat, Alexandra M., Xu, Jianming, Kuśnierczyk, Anna, Vågbø, Cathrine B., Schär, Primo, Schuermann, David
Publicado 2020

DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways

por Noreen, Faiza, Küng, Taya, Tornillo, Luigi, Parker, Hannah, Silva, Miguel, Weis, Stefan, Marra, Giancarlo, Rad, Roland, Truninger, Kaspar, Schär, Primo
Publicado 2019

Assessment of Genotoxicity in Human Cells Exposed to Modulated Electromagnetic Fields of Wireless Communication Devices

por Schuermann, David, Ziemann, Christina, Barekati, Zeinab, Capstick, Myles, Oertel, Antje, Focke, Frauke, Murbach, Manuel, Kuster, Niels, Dasenbrock, Clemens, Schär, Primo
Publicado 2020

Gadd45a promotes DNA demethylation through TDG

por Li, Zheng, Gu, Tian-Peng, Weber, Alain R., Shen, Jia-Zhen, Li, Bin-Zhong, Xie, Zhi-Guo, Yin, Ruichuan, Guo, Fan, Liu, Xiaomeng, Tang, Fuchou, Wang, Hailin, Schär, Primo, Xu, Guo-Liang
Publicado 2015

Hierarchical contribution of individual lifestyle factors and their interactions on adenomatous and serrated polyp risk

por Kim, Jihee, Nath, Kirti, Schmidlin, Kurt, Schaufelberger, Helen, Quattropani, Christiana, Vannini, Simone, Mossi, Sandro, Thumshirn, Miriam, Manz, Michael, Litichevskiy, Lev, Fan, Jiaxin, Dmitrieva-Posocco, Oxana, Li, Mingyao, Levy, Maayan, Schär, Primo, Zwahlen, Marcel, Thaiss, Christoph A., Truninger, Kaspar
Publicado 2023

T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif

por Lucey, Marie J., Chen, Dongsheng, Lopez-Garcia, Jorge, Hart, Stephen M., Phoenix, Fladia, Al-Jehani, Rajai, Alao, John P., White, Roger, Kindle, Karin B., Losson, Régine, Chambon, Pierre, Parker, Malcolm G., Schär, Primo, Heery, David M., Buluwela, Lakjaya, Ali, Simak
Publicado 2005