HIV-1 Vif N-terminal Motif is required for recruitment of Cul5 to Suppress APOBEC3

por Evans, Sean L, Schön, Arne, Gao, Qimeng, Han, Xue, Zhou, Xiaohong, Freire, Ernesto, Yu, Xiao-Fang
Publicado 2014

Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis

por Wang, Shusheng, Ketcham, Stephanie A., Schön, Arne, Goodman, Benjamin, Wang, Yueju, Yates, John, Freire, Ernesto, Schroer, Trina A., Zheng, Yixian
Publicado 2013

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

por Courter, Joel R., Madani, Navid, Sodroski, Joseph, Schön, Arne, Freire, Ernesto, Kwong, Peter D., Hendrickson, Wayne A., Chaiken, Irwin M., LaLonde, Judith M., Smith, Amos B.
Publicado 2014

Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies

por Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Chen, Shen-En, Naser-Tavakolian, Aurash, Schön, Arne, Freire, Ernesto, Hayashi, Yoshio
Publicado 2013

The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

por Herschhorn, Alon, Gu, Christopher, Moraca, Francesca, Ma, Xiaochu, Farrell, Mark, Smith, Amos B., Pancera, Marie, Kwong, Peter D., Schön, Arne, Freire, Ernesto, Abrams, Cameron, Blanchard, Scott C., Mothes, Walther, Sodroski, Joseph G.
Publicado 2017

Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

por Herschhorn, Alon, Gu, Christopher, Moraca, Francesca, Ma, Xiaochu, Farrell, Mark, Smith, Amos B., Pancera, Marie, Kwong, Peter D., Schön, Arne, Freire, Ernesto, Abrams, Cameron, Blanchard, Scott C., Mothes, Walther, Sodroski, Joseph G.
Publicado 2018

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study

por Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Kiso, Yoshiaki, Kawasaki, Yuko, Chen, Shen-En, Naser-Tavakolian, Aurash, Schön, Arne, Freire, Ernesto, Hayashi, Yoshio
Publicado 2013

Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein

por Wang, Lawrence T., Pereira, Lais S., Kiyuka, Patience K., Schön, Arne, Kisalu, Neville K., Vistein, Rachel, Dillon, Marlon, Bonilla, Brian G., Molina-Cruz, Alvaro, Barillas-Mury, Carolina, Tan, Joshua, Idris, Azza H., Francica, Joseph R., Seder, Robert A.
Publicado 2021

Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes

por Verardi, Raffaello, Lindesmith, Lisa C., Tsybovsky, Yaroslav, Gorman, Jason, Chuang, Gwo-Yu, Edwards, Caitlin E., Brewer-Jensen, Paul D., Mallory, Michael L., Ou, Li, Schön, Arne, Shi, Wei, Tully, Ena S., Georgiou, George, Baric, Ralph S., Kwong, Peter D.
Publicado 2020

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention

por Kisalu, Neville K., Pereira, Lais D., Ernste, Keenan, Flores-Garcia, Yevel, Idris, Azza H., Asokan, Mangaiarkarasi, Dillon, Marlon, MacDonald, Scott, Shi, Wei, Chen, Xuejun, Pegu, Amarendra, Schön, Arne, Zavala, Fidel, Balazs, Alejandro B., Francica, Joseph R., Seder, Robert A.
Publicado 2021

Development of high-affinity nanobodies specific for Na(V)1.4 and Na(V)1.5 voltage-gated sodium channel isoforms

por Srinivasan, Lakshmi, Alzogaray, Vanina, Selvakumar, Dakshnamurthy, Nathan, Sara, Yoder, Jesse B., Wright, Katharine M., Klinke, Sebastián, Nwafor, Justin N., Labanda, María S., Goldbaum, Fernando A., Schön, Arne, Freire, Ernesto, Tomaselli, Gordon F., Amzel, L. Mario, Ben-Johny, Manu, Gabelli, Sandra B.
Publicado 2022

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

por Bartolini, Desirée, De Franco, Francesca, Torquato, Pierangelo, Marinelli, Rita, Cerra, Bruno, Ronchetti, Riccardo, Schon, Arne, Fallarino, Francesca, De Luca, Antonella, Bellezza, Guido, Ferri, Ivana, Sidoni, Angelo, Walton, William G., Pellock, Samuel J., Redinbo, Matthew R., Mani, Sridhar, Pellicciari, Roberto, Gioiello, Antimo, Galli, Francesco
Publicado 2020

Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection

por Aguirre-Botero, Manuela C., Wang, Lawrence T., Formaglio, Pauline, Aliprandini, Eduardo, Thiberge, Jean-Michel, Schön, Arne, Flores-Garcia, Yevel, Mathis-Torres, Shamika, Flynn, Barbara J., da Silva Pereira, Lais, Le Duff, Yann, Hurley, Mathew, Nacer, Adéla, Bowyer, Paul W., Zavala, Fidel, Idris, Azza H., Francica, Joseph R., Seder, Robert A., Amino, Rogerio
Publicado 2023

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

por Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, Herschhorn, Alon, Sodroski, Joseph, Bailer, Robert T., Doria-Rose, Nicole A., Mascola, John R., Langley, David R., Kwong, Peter D.
Publicado 2019

Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2

por Prévost, Jérémie, Richard, Jonathan, Gasser, Romain, Ding, Shilei, Fage, Clément, Anand, Sai Priya, Adam, Damien, Gupta Vergara, Natasha, Tauzin, Alexandra, Benlarbi, Mehdi, Gong, Shang Yu, Goyette, Guillaume, Privé, Anik, Moreira, Sandrine, Charest, Hugues, Roger, Michel, Mothes, Walther, Pazgier, Marzena, Brochiero, Emmanuelle, Boivin, Guy, Abrams, Cameron F., Schön, Arne, Finzi, Andrés
Publicado 2021

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529

por Pancera, Marie, Lai, Yen-Ting, Bylund, Tatsiana, Druz, Aliaksandr, Narpala, Sandeep, O’Dell, Sijy, Schön, Arne, Bailer, Robert T., Chuang, Gwo-Yu, Geng, Hui, Louder, Mark K., Rawi, Reda, Soumana, Djade I., Finzi, Andrés, Herschhorn, Alon, Madani, Navid, Sodroski, Joseph, Freire, Ernesto, Langley, David R., Mascola, John R., McDermott, Adrian B., Kwong, Peter D.
Publicado 2017

Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

por Shi, Wei, Wang, Lingshu, Zhou, Tongqing, Sastry, Mallika, Yang, Eun Sung, Zhang, Yi, Chen, Man, Chen, Xuejun, Choe, Misook, Creanga, Adrian, Leung, Kwan, Olia, Adam S., Pegu, Amarendra, Rawi, Reda, Schön, Arne, Shen, Chen-Hsiang, Stancofski, Erik-Stephane D., Talana, Chloe Adrienna, Teng, I-Ting, Wang, Shuishu, Corbett, Kizzmekia S., Tsybovsky, Yaroslav, Mascola, John R., Kwong, Peter D.
Publicado 2022

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

por Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site

por Banach, Bailey B., Pletnev, Sergei, Olia, Adam S., Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A., Nguyen, Thuy Duong, Fahad, Ahmed S., Lee, Myungjin, Lin, Bob C., Liu, Tracy, Louder, Mark K., Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R., Chuang, Gwo-Yu, Mascola, John R., Kwong, Peter D., DeKosky, Brandon J.
Publicado 2023

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency

por Zhang, Baoshan, Gorman, Jason, Kwon, Young D., Pegu, Amarendra, Chao, Cara W., Liu, Tracy, Asokan, Mangaiarkarasi, Bender, Michael F., Bylund, Tatsiana, Damron, Leland, Gollapudi, Deepika, Lei, Paula, Li, Yile, Liu, Cuiping, Louder, Mark K., McKee, Krisha, Olia, Adam S., Rawi, Reda, Schön, Arne, Wang, Shuishu, Yang, Eun Sung, Yang, Yongping, Carlton, Kevin, Doria-Rose, Nicole A., Shapiro, Lawrence, Seaman, Michael S., Mascola, John R., Kwong, Peter D.
Publicado 2023