Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

por Lamb, Daniel, Schüttelkopf, Alexander W, van Aalten, Daan MF, Brighty, David W
Publicado 2008

Human OGA binds substrates in a conserved peptide recognition groove

por Schimpl, Marianne, Schüttelkopf, Alexander W., Borodkin, Vladimir S., van Aalten, Daan M. F.
Publicado 2010

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

por Lamb, Daniel, Schüttelkopf, Alexander W., van Aalten, Daan M. F., Brighty, David W.
Publicado 2011

Comparative structural analysis of retroviral fusion proteins identifies regions that modulate membrane fusion: a potential retroviral achilles heal?

por Lamb, Daniel, Schüttelkopf, Alexander W, van Aalten, Daan M F, Brighty, David W
Publicado 2011

Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis

por Striebeck, Alexander, Robinson, David A., Schüttelkopf, Alexander W., van Aalten, Daan M. F.
Publicado 2013

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

por Rao, Francesco V., Schüttelkopf, Alexander W., Dorfmueller, Helge C., Ferenbach, Andrew T., Navratilova, Iva, van Aalten, Daan M. F.
Publicado 2013

Acetazolamide-based fungal chitinase inhibitors

por Schüttelkopf, Alexander W., Gros, Ludovic, Blair, David E., Frearson, Julie A., van Aalten, Daan M.F., Gilbert, Ian H.
Publicado 2010

Structural insights into mechanism and specificity of O-GlcNAc transferase

por Clarke, Andrew J, Hurtado-Guerrero, Ramon, Pathak, Shalini, Schüttelkopf, Alexander W, Borodkin, Vladimir, Shepherd, Sharon M, Ibrahim, Adel F M, van Aalten, Daan M F
Publicado 2008

O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis

por Schimpl, Marianne, Zheng, Xiaowei, Borodkin, Vladimir S., Blair, David E., Ferenbach, Andrew T., Schüttelkopf, Alexander W., Navratilova, Iva, Aristotelous, Tonia, Albarbarawi, Osama, Robinson, David A., Macnaughtan, Megan A., van Aalten, Daan M.F.
Publicado 2012

A novel small-molecule MRCK inhibitor blocks cancer cell invasion

por Unbekandt, Mathieu, Croft, Daniel R, Crighton, Diane, Mezna, Mokdad, McArthur, Duncan, McConnell, Patricia, Schüttelkopf, Alexander W, Belshaw, Simone, Pannifer, Andrew, Sime, Mairi, Bower, Justin, Drysdale, Martin, Olson, Michael F
Publicado 2014

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents

por Francis, Stuart, Croft, Daniel, Schüttelkopf, Alexander W., Parry, Charles, Pugliese, Angelo, Cameron, Ken, Claydon, Sophie, Drysdale, Martin, Gardner, Claire, Gohlke, Andrea, Goodwin, Gillian, Gray, Christopher H., Konczal, Jennifer, McDonald, Laura, Mezna, Mokdad, Pannifer, Andrew, Paul, Nikki R., Machesky, Laura, McKinnon, Heather, Bower, Justin
Publicado 2019