Pharmacogenomics: a key component of personalized therapy

por Schwab, Matthias, Schaeffeler, Elke
Publicado 2012

Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy

por Fisel, Pascale, Schaeffeler, Elke, Schwab, Matthias
Publicado 2018

Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)

por Nies, Anne T., Hofmann, Ute, Resch, Claudia, Schaeffeler, Elke, Rius, Maria, Schwab, Matthias
Publicado 2011

The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

por Nies, Anne T., Weiss, Stefan, Schaeffeler, Elke, Hannemann, Anke, Völker, Uwe, Wallaschofski, Henri, Schwab, Matthias
Publicado 2020

Myocardial extracellular volume fraction (ECV) measurements based on T1-mapping in healthy monozygotic twins - another similarity or rather disagreement in twins?

por Florian, Anca R, Ludwig, Anna, Rösch, Sabine, Schaeffeler, Elke, Schwab, Matthias, Sechtem, Udo, Yilmaz, Ali
Publicado 2015

Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin

por Hsin, Chih-hsuan, Stoffel, Marc S., Gazzaz, Malaz, Schaeffeler, Elke, Schwab, Matthias, Fuhr, Uwe, Taubert, Max
Publicado 2020

Platelet miRNAs: differential expression in coronary artery disease and associations with course of left ventricular systolic function

por Goldschmied, Andreas, Drotleff, Bernhard, Winter, Stefan, Schaeffeler, Elke, Schwab, Matthias, Gawaz, Meinrad, Geisler, Tobias, Rath, Dominik
Publicado 2023

Variants of PEAR1 Are Associated With Outcome in Patients With ACS and Stable CAD Undergoing PCI

por Stimpfle, Fabian, Bauer, Maike, Rath, Dominik, Schaeffeler, Elke, Schwab, Matthias, Gawaz, Meinrad, Winter, Stefan, Geisler, Tobias
Publicado 2018

Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach

por Florian, Anca, Patrascu, Alexandru, Tremmel, Roman, Rösch, Sabine, Sechtem, Udo, Schwab, Matthias, Schaeffeler, Elke, Yilmaz, Ali
Publicado 2018

Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival

por Kandabarau, Siarhei, Leiz, Janna, Krohn, Knut, Winter, Stefan, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke, Edemir, Bayram
Publicado 2019

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

por Nies, Anne T, Niemi, Mikko, Burk, Oliver, Winter, Stefan, Zanger, Ulrich M, Stieger, Bruno, Schwab, Matthias, Schaeffeler, Elke
Publicado 2013

Identification of cardiomyopathy associated circulating miRNA biomarkers in patients with muscular dystrophy using a complementary cardiovascular magnetic resonance and plasma prof...

por Becker, Svetlana, Florian, Anca, Patrascu, Alexandru, Rösch, Sabine, Waltenberger, Johannes, Sechtem, Udo, Schwab, Matthias, Schaeffeler, Elke, Yilmaz, Ali
Publicado 2016

Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry

por Schaeffeler, Elke, Jaeger, Simon U., Klumpp, Verena, Yang, Jun J., Igel, Svitlana, Hinze, Laura, Stanulla, Martin, Schwab, Matthias
Publicado 2019

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

por Mooij, Miriam G., Nies, Anne T., Knibbe, Catherijne A. J., Schaeffeler, Elke, Tibboel, Dick, Schwab, Matthias, de Wildt, Saskia N.
Publicado 2015

SDF1 Polymorphisms Influence Outcome in Patients with Symptomatic Cardiovascular Disease

por Rath, Dominik, Schaeffeler, Elke, Winter, Stefan, Hewer, Jens, Müller, Karin, Droppa, Michal, Stimpfle, Fabian, Gawaz, Meinrad, Schwab, Matthias, Geisler, Tobias
Publicado 2016

Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn’s Disease

por Jaeger, Simon U., Schaeffeler, Elke, Winter, Stefan, Tremmel, Roman, Schölmerich, Jürgen, Malek, Nisar, Stange, Eduard F., Schwab, Matthias, Wehkamp, Jan
Publicado 2018

No association of genetic variants in TLR4, TNF-α, IL10, IFN-γ, and IL37 in cytomegalovirus-positive renal allograft recipients with active CMV infection—Subanalysis of the prospec...

por Mazzola, Pascale, Schaeffeler, Elke, Witzke, Oliver, Nitschke, Martin, Kliem, Volker, Zortel, Max, Wagner, Eva-Maria, Schwab, Matthias, Hauser, Ingeborg A.
Publicado 2021

A Variant of the SLC10A2 Gene Encoding the Apical Sodium-Dependent Bile Acid Transporter Is a Risk Factor for Gallstone Disease

por Renner, Olga, Harsch, Simone, Schaeffeler, Elke, Winter, Stefan, Schwab, Matthias, Krawczyk, Marcin, Rosendahl, Jonas, Wittenburg, Henning, Lammert, Frank, Stange, Eduard F.
Publicado 2009

A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

por Klein, Kathrin, Tremmel, Roman, Winter, Stefan, Fehr, Sarah, Battke, Florian, Scheurenbrand, Tim, Schaeffeler, Elke, Biskup, Saskia, Schwab, Matthias, Zanger, Ulrich M.
Publicado 2019

Clinical Trial: CYP2D6 Related Dose Escalation of Tamoxifen in Breast Cancer Patients With Iranian Ethnic Background Resulted in Increased Concentrations of Tamoxifen and Its Metab...

por Khalaj, Zahra, Baratieh, Zohreh, Nikpour, Parvaneh, Schwab, Matthias, Schaeffeler, Elke, Mokarian, Fariborz, Khanahmad, Hossein, Salehi, Rasoul, Mürdter, Thomas E., Salehi, Mansoor
Publicado 2019