Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus

por Colbers, Angela, Mirochnick, Mark, Schalkwijk, Stein, Penazzato, Martina, Townsend, Claire, Burger, David
Publicado 2019

Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies

por Wasmann, Roeland E., Svensson, Elin M., Schalkwijk, Stein J., Brüggemann, Roger J., ter Heine, Rob
Publicado 2020

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling

por Freriksen, Jolien J.M., Schalkwijk, Stein, Colbers, Angela P., Abduljalil, Khaled, Russel, Frans G.M., Burger, David M., Greupink, Rick
Publicado 2020

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

por Schalkwijk, Stein, Buaben, Aaron O., Freriksen, Jolien J. M., Colbers, Angela P., Burger, David M., Greupink, Rick, Russel, Frans G. M.
Publicado 2017

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps

por van der Galiën, Ruben, ter Heine, Rob, Greupink, Rick, Schalkwijk, Stein J., van Herwaarden, Antonius E., Colbers, Angela, Burger, David M.
Publicado 2018

Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug‐Drug Interactions and Pediatric Dose Regimens

por Cohen‐Rabbie, Sarit, Zhou, Li, Vishwanathan, Karthick, Wild, Martin, Xu, Sherrie, Freshwater, Tomoko, Jain, Lokesh, Schalkwijk, Stein, Tomkinson, Helen, Zhou, Diansong
Publicado 2021

Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam

por Ren, Song, Vishwanathan, Karthick, Cantarini, Mireille, Frewer, Paul, Hara, Indira, Scarfe, Graeme, Burke, Wendy, Schalkwijk, Stein, Li, Yan, Han, David, Goldwater, Ronald
Publicado 2021

The Impact of Dose and Simultaneous Use of Acid-Reducing Agents on the Effectiveness of Vemurafenib in Metastatic BRAF V600 Mutated Melanoma: a Retrospective Cohort Study

por Knapen, Lotte M., Koornstra, Rutger H. T., Driessen, Johanna H. M., van Vlijmen, Bas, Croes, Sander, Schalkwijk, Stein, Colbers, Angela, Gerritsen, Winald R., Burger, David M., de Vries, Frank, van Erp, Nielka P.
Publicado 2018

Safety, tolerability, and pharmacokinetics of Aurora kinase B inhibitor AZD2811: a phase 1 dose-finding study in patients with advanced solid tumours

por Johnson, Melissa L., Wang, Judy S., Falchook, Gerald, Greenlees, Carol, Jones, Suzanne, Strickland, Donald, Fabbri, Giulia, Kennedy, Caroline, Elizabeth Pease, J., Sainsbury, Liz, MacDonald, Alexander, Schalkwijk, Stein, Szekeres, Philip, Cosaert, Jan, Burris, Howard
Publicado 2023

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women

por Schalkwijk, Stein, ter Heine, Rob, Colbers, Angela C., Huitema, Alwin D. R., Denti, Paolo, Dooley, Kelly E., Capparelli, Edmund, Best, Brookie M., Cressey, Tim R., Greupink, Rick, Russel, Frans G. M., Mirochnick, Mark, Burger, David M.
Publicado 2018

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women

por Mulligan, Nikki, Schalkwijk, Stein, Best, Brookie M., Colbers, Angela, Wang, Jiajia, Capparelli, Edmund V., Moltó, José, Stek, Alice M., Taylor, Graham, Smith, Elizabeth, Hidalgo Tenorio, Carmen, Chakhtoura, Nahida, van Kasteren, Marjo, Fletcher, Courtney V., Mirochnick, Mark, Burger, David
Publicado 2016