Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

por Price, Madeline J., Patterson, Dillon G., Scharer, Christopher D., Boss, Jeremy M.
Publicado 2018

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

por Barwick, Benjamin G., Scharer, Christopher D., Bally, Alexander P.R., Boss, Jeremy M.
Publicado 2016

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

por Scharer, Christopher D., Barwick, Benjamin G., Guo, Muyao, Bally, Alexander P. R., Boss, Jeremy M.
Publicado 2018

Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment

por Collins, Christopher M., Scharer, Christopher D., Murphy, Thomas J., Boss, Jeremy M., Speck, Samuel H.
Publicado 2020

Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment

por Scharer, Christopher D., Choi, Nancy M., Barwick, Benjamin G., Majumder, Parimal, Lohsen, Sarah, Boss, Jeremy M.
Publicado 2015

A super enhancer controls expression and chromatin architecture within the MHC class II locus

por Majumder, Parimal, Lee, Joshua T., Rahmberg, Andrew R., Kumar, Gaurav, Mi, Tian, Scharer, Christopher D., Boss, Jeremy M.
Publicado 2019

Antibody-secreting cell destiny emerges during the initial stages of B-cell activation

por Scharer, Christopher D., Patterson, Dillon G., Mi, Tian, Price, Madeline J., Hicks, Sakeenah L., Boss, Jeremy M.
Publicado 2020

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

por Scharer, Christopher D., Fortner, Karen A., Dragon, Julie A., Tighe, Scott, Boss, Jeremy M., Budd, Ralph C.
Publicado 2020

Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells

por Scharer, Christopher D, Laycock, Noelani, Osunkoya, Adeboye O, Logani, Sanjay, McDonald, John F, Benigno, Benedict B, Moreno, Carlos S
Publicado 2008

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells

por Scharer, Christopher D., Blalock, Emily L., Barwick, Benjamin G., Haines, Robert R., Wei, Chungwen, Sanz, Ignacio, Boss, Jeremy M.
Publicado 2016

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

por Lohsen, Sarah, Majumder, Parimal, Scharer, Christopher D., Barwick, Benjamin G., Austin, James W., Zinzow-Kramer, Wendy M., Boss, Jeremy M.
Publicado 2014

Transcriptomic and epigenomic dynamics associated with development of human iPSC-derived GABAergic interneurons

por Inglis, George Andrew S, Zhou, Ying, Patterson, Dillon G, Scharer, Christopher D, Han, Yanfei, Boss, Jeremy M, Wen, Zhexing, Escayg, Andrew
Publicado 2020

Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential

por Rose, James R., Akdogan-Ozdilek, Bagdeser, Rahmberg, Andrew R., Powell, Michael D., Hicks, Sakeenah L., Scharer, Christopher D., Boss, Jeremy M.
Publicado 2023

CRISPR/Cas9 editing reveals IRF8 regulated gene signatures restraining plasmablast differentiation

por Zuo, Zhihong, Kania, Anna K., Patterson, Dillon G., Hicks, Sakeenah L., Maurer, Jeffrey, Gupta, Mansi, Boss, Jeremy M., Scharer, Christopher D.
Publicado 2023

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8(+) T cells

por Hayward, Sarah L., Scharer, Christopher D., Cartwright, Emily K., Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M., Kohlmeier, Jacob E.
Publicado 2020

Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness

por Eggert, Joel, Zinzow-Kramer, Wendy M., Hu, Yuesong, Tsai, Yuan-Li, Weiss, Arthur, Salaita, Khalid, Scharer, Christopher D., Au-Yeung, Byron B.
Publicado 2023

Adipocyte-mediated epigenomic instability in human T-ALL cells is cytotoxic and phenocopied by epigenetic-modifying drugs

por Lee, Miyoung, Geitgey, Delaney K., Hamilton, Jamie A. G., Boss, Jeremy M., Scharer, Christopher D., Spangle, Jennifer M., Haynes, Karmella A., Henry, Curtis J.
Publicado 2022

Chitinase-3-like 1 regulates T(H)2 cells, T(FH) cells and IgE responses to helminth infection

por Curtiss, Miranda L., Rosenberg, Alexander F., Scharer, Christopher D., Mousseau, Betty, Benavides, Natalia A. Ballesteros, Bradley, John E., León, Beatriz, Steele, Chad, Randall, Troy D., Lund, Frances E.
Publicado 2023

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation

por Barwick, Benjamin G., Scharer, Christopher D., Martinez, Ryan J., Price, Madeline J., Wein, Alexander N., Haines, Robert R., Bally, Alexander P. R., Kohlmeier, Jacob E., Boss, Jeremy M.
Publicado 2018

Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence

por Gokcumen, Omer, Zhu, Qihui, Mulder, Lubbertus C. F., Iskow, Rebecca C., Austermann, Christian, Scharer, Christopher D., Raj, Towfique, Boss, Jeremy M., Sunyaev, Shamil, Price, Alkes, Stranger, Barbara, Simon, Viviana, Lee, Charles
Publicado 2013