Brazilian immunology in Caxambu: beyond vaccination, a tribute to the pioneers of basic research in Chagas disease

por Scharfstein, Julio
Publicado 2022

The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosom...

por Scharfstein, Julio, Andrade, Daniele, Svensjö, Erik, Oliveira, Ana Carolina, Nascimento, Clarissa R.
Publicado 2013

Ecotin-Like ISP of L. major Promastigotes Fine-Tunes Macrophage Phagocytosis by Limiting the Pericellular Release of Bradykinin from Surface-Bound Kininogens: A Survival Strategy B...

por Svensjö, Erik, Nogueira de Almeida, Larissa, Vellasco, Lucas, Juliano, Luiz, Scharfstein, Julio
Publicado 2014

P2Y14 Receptor as a Target for Neutrophilia Attenuation in Severe COVID-19 Cases: From Hematopoietic Stem Cell Recruitment and Chemotaxis to Thrombo‐inflammation

por Lintzmaier Petiz, Lyvia, Glaser, Talita, Scharfstein, Julio, Ratajczak, Mariusz Z., Ulrich, Henning
Publicado 2021

Review of the World Class Parasites Book Series

por Cox, Frank EG, McMahon-Pratt, Diane, Chang, Kwang-Poo, Goldenberg, Samuel, Scharfstein, Julio
Publicado 2003

Resistance to visceral leishmaniasis is severely compromised in mice deficient of bradykinin B2-receptors

por Nico, Dirlei, Feijó, Daniel Ferreira, Maran, Naiara, Morrot, Alexandre, Scharfstein, Julio, Palatnik, Marcos, Palatnik-de-Sousa, Clarisa Beatriz
Publicado 2012

Host Cell Invasion by TRYPANOSOMA cRUZI Is Potentiated by Activation of Bradykinin B(2) Receptors

por Scharfstein, Julio, Schmitz, Veronica, Morandi, Veronica, Capella, Marcia M. A., Lima, Ana Paula C. A., Morrot, Alexandre, Juliano, Luiz, Müller-Esterl, Werner
Publicado 2000

Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Act...

por Silva, Leandro S., Pinheiro, Alessandro S., Teixeira, Douglas E., Silva-Aguiar, Rodrigo P., Peruchetti, Diogo B., Scharfstein, Julio, Caruso-Neves, Celso, Pinheiro, Ana Acacia S.
Publicado 2019

Bradykinin B(2) Receptors of Dendritic Cells, Acting as Sensors of Kinins Proteolytically Released by Trypanosoma cruzi, Are Critical for the Development of Protective Type-1 Respo...

por Monteiro, Ana Carolina, Schmitz, Verônica, Morrot, Alexandre, de Arruda, Luciana Barros, Nagajyothi, Fnu, Granato, Alessandra, Pesquero, João B, Müller-Esterl, Werner, Tanowitz, Herbert B, Scharfstein, Julio
Publicado 2007

Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption

por Johnson, Larry, Almeida-da-Silva, Cássio Luiz Coutinho, Takiya, Christina Maeda, Figliuolo, Vanessa, Rocha, Gustavo Miranda, Weissmüller, Gilberto, Scharfstein, Julio, Coutinho-Silva, Robson, Ojcius, David M.
Publicado 2018

Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis

por Motta Junior, Jarbas da Silva, Miggiolaro, Anna Flavia Ribeiro dos Santos, Nagashima, Seigo, de Paula, Caroline Busatta Vaz, Baena, Cristina Pellegrino, Scharfstein, Julio, de Noronha, Lucia
Publicado 2020

The role of conserved residues of chagasin in the inhibition of cysteine peptidases

por dos Reis, Flavia C.G., Smith, Brian O., Santos, Camila C., Costa, Tatiana, F.R., Scharfstein, Julio, Coombs, Graham H., Mottram, Jeremy C., Lima, Ana Paula C.A.
Publicado 2008

Protease Activated Receptor Signaling Is Required for African Trypanosome Traversal of Human Brain Microvascular Endothelial Cells

por Grab, Dennis J., Garcia-Garcia, Jose C., Nikolskaia, Olga V., Kim, Yuri V., Brown, Amanda, Pardo, Carlos A., Zhang, Yongqing, Becker, Kevin G., Wilson, Brenda A., de A. Lima, Ana Paula C., Scharfstein, Julio, Dumler, J. Stephen
Publicado 2009

Sheltered in Stromal Tissue Cells, Trypanosoma cruzi Orchestrates Inflammatory Neovascularization via Activation of the Mast Cell Chymase Pathway

por Vellasco, Lucas, Svensjö, Erik, Bulant, Carlos Alberto, Blanco, Pablo Javier, Nogueira, Fábio, Domont, Gilberto, de Almeida, Natália Pinto, Nascimento, Clarissa Rodrigues, Silva-dos-Santos, Danielle, Carvalho-Pinto, Carla Eponina, Medei, Emiliano Horácio, Almeida, Igor C., Scharfstein, Julio
Publicado 2022

Contact System Activation in Plasma from Dengue Patients Might Harness Endothelial Virus Replication through the Signaling of Bradykinin Receptors

por Coelho, Sharton V. A., Rust, Naiara M., Vellasco, Lucas, Papa, Michelle P., Pereira, Aline S. G., da Silva Palazzo, Matheus Ferreira, Juliano, Maria Aparecida, Costa, Simone M., Alves, Ada M. B., Cordeiro, Marli T., Marques, Ernesto T. A., Scharfstein, Júlio, de Arruda, Luciana B.
Publicado 2021

Pleiotropic antifibrotic actions of aspirin-triggered resolvin D1 in the lungs

por Guilherme, Rafael F., Silva, José Bruno N.F., Waclawiack, Ingrid, Fraga-Junior, Vanderlei S., Nogueira, Thaís O., Pecli, Cyntia, Araújo-Silva, Carlla A., Magalhães, Nathalia S., Lemos, Felipe S., Bulant, Carlos A., Blanco, Pablo J., Serra, Rafaela, Svensjö, Erik, Scharfstein, Júlio, Moraes, João A., Canetti, Claudio, Benjamim, Claudia F.
Publicado 2023

Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy

por Oliveira, Ana Carolina, Vicentino, Amanda Roberta Revoredo, Andrade, Daniele, Pereira, Isabela Resende, Saboia-Vahia, Leonardo, Moreira, Otacílio da Cruz, Carvalho-Pinto, Carla Eponina, da Mota, Julia Barbalho, Maciel, Leonardo, Vilar-Pereira, Glaucia, Pesquero, João B., Lannes-Vieira, Joseli, Sirois, Pierre, Campos de Carvalho, Antônio Carlos, Scharfstein, Julio
Publicado 2023

Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease

por Nascimento, Clarissa R., Andrade, Daniele, Carvalho-Pinto, Carla Eponina, Serra, Rafaela Rangel, Vellasco, Lucas, Brasil, Guilherme, Ramos-Junior, Erivan Schnaider, da Mota, Julia Barbalho, Almeida, Larissa Nogueira, Andrade, Marcus V., Correia Soeiro, Maria de Nazaré, Juliano, Luiz, Alvarenga, Patrícia Hessab, Oliveira, Ana Carolina, Sicuro, Fernando Lencastre, de Carvalho, Antônio C. Campos, Svensjö, Erik, Scharfstein, Julio
Publicado 2017

High mobility group box 1, ATP, lipid mediators, and tissue factor are elevated in COVID‐19 patients: HMGB1 as a biomarker of worst prognosis

por Vicentino, Amanda Roberta Revoredo, Fraga‐Junior, Vanderlei da Silva, Palazzo, Matheus, Tasmo, Natalia Recardo Amorim, Rodrigues, Danielle A. S., Barroso, Shana Priscila Coutinho, Ferreira, Sâmila Natiane, Neves‐Borges, Anna Cristina, Allonso, Diego, Fantappié, Marcelo Rosado, Scharfstein, Julio, Oliveira, Ana Carolina, Vianna‐Jorge, Rosane, Vale, André Macedo, Coutinho‐Silva, Robson, Savio, Luiz Eduardo Baggio, Canetti, Claudio, Benjamim, Claudia Farias
Publicado 2023