Biophysical Insights into the Inhibitory Mechanism of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

por Schauer, Grant, Leuba, Sanford, Sluis-Cremer, Nicolas
Publicado 2013

Visualization of uracils created by APOBEC3A using UdgX shows colocalization with RPA at stalled replication forks

por Stewart, Jessica A, Schauer, Grant, Bhagwat, Ashok S
Publicado 2020

Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding

por Graham, Brian W., Schauer, Grant D., Leuba, Sanford H., Trakselis, Michael A.
Publicado 2011

Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence

por Schauer, Grant D., Huber, Kelly D., Leuba, Sanford H., Sluis-Cremer, Nicolas
Publicado 2014

Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome

por Yuan, Zuanning, Georgescu, Roxana, Schauer, Grant D., O’Donnell, Michael E., Li, Huilin
Publicado 2020

PcrA-mediated disruption of RecA nucleoprotein filaments—essential role of the ATPase activity of RecA

por Fagerburg, Matt V., Schauer, Grant D., Thickman, Karen R., Bianco, Piero R., Khan, Saleem A., Leuba, Sanford H., Anand, Syam P.
Publicado 2012

Early integration of the individual student in academic activities: a novel classroom concept for graduate education in molecular biophysics and structural biology

por Leuba, Sanford H, Carney, Sean M, Dahlburg, Elizabeth M, Eells, Rebecca J, Ghodke, Harshad, Yanamala, Naveena, Schauer, Grant, Klein-Seetharaman, Judith
Publicado 2014

Replisome bypass of a protein-based R-loop block by Pif1

por Schauer, Grant D., Spenkelink, Lisanne M., Lewis, Jacob S., Yurieva, Olga, Mueller, Stefan H., van Oijen, Antoine M., O’Donnell, Michael E.
Publicado 2020

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

por Georgescu, Roxana E, Schauer, Grant D, Yao, Nina Y, Langston, Lance D, Yurieva, Olga, Zhang, Dan, Finkelstein, Jeff, O'Donnell, Mike E
Publicado 2015

Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks

por Langston, Lance D, Mayle, Ryan, Schauer, Grant D, Yurieva, Olga, Zhang, Daniel, Yao, Nina Y, Georgescu, Roxana E, O'Donnell, Mike E
Publicado 2017

Nuclease dead Cas9 is a programmable roadblock for DNA replication

por Whinn, Kelsey S., Kaur, Gurleen, Lewis, Jacob S., Schauer, Grant D., Mueller, Stefan H., Jergic, Slobodan, Maynard, Hamish, Gan, Zhong Yan, Naganbabu, Matharishwan, Bruchez, Marcel P., O’Donnell, Michael E., Dixon, Nicholas E., van Oijen, Antoine M., Ghodke, Harshad
Publicado 2019