Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation

por Elliott, J. Michael, Rouge, Lionel, Wiesmann, Christian, Scheer, Justin M.
Publicado 2009

Discovery Strategies to Maximize the Clinical Potential of T-Cell Engaging Antibodies for the Treatment of Solid Tumors

por Voynov, Vladimir, Adam, Paul J., Nixon, Andrew E., Scheer, Justin M.
Publicado 2020

Intrinsic physicochemical profile of marketed antibody-based biotherapeutics

por Ahmed, Lucky, Gupta, Priyanka, Martin, Kyle P., Scheer, Justin M., Nixon, Andrew E., Kumar, Sandeep
Publicado 2021

Reorienting the Fab Domains of Trastuzumab Results in Potent HER2 Activators

por Scheer, Justin M., Sandoval, Wendy, Elliott, J. Michael, Shao, Lily, Luis, Elizabeth, Lewin-Koh, Sock-Cheng, Schaefer, Gabriele, Vandlen, Richard
Publicado 2012

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity

por Shatz, Whitney, Chung, Shan, Li, Bing, Marshall, Brett, Tejada, Max, Phung, Wilson, Sandoval, Wendy, Kelley, Robert F, Scheer, Justin M
Publicado 2013

Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye

por Shatz, Whitney, Hass, Philip E., Peer, Nikhil, Paluch, Maciej T., Blanchette, Craig, Han, Guanghui, Sandoval, Wendy, Morando, Ashley, Loyet, Kelly M., Bantseev, Vladimir, Booler, Helen, Crowell, Susan, Kamath, Amrita, Scheer, Justin M., Kelley, Robert F.
Publicado 2019

Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling

por Jackman, Janet, Chen, Yongmei, Huang, Arthur, Moffat, Barbara, Scheer, Justin M., Leong, Steven R., Lee, Wyne P., Zhang, Juan, Sharma, Navneet, Lu, Yanmei, Iyer, Suhasini, Shields, Robert L., Chiang, Nancy, Bauer, Michele C., Wadley, Diana, Roose-Girma, Merone, Vandlen, Richard, Yansura, Daniel G., Wu, Yan, Wu, Lawren C.
Publicado 2010

Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye

por Tesar, Devin, Luoma, Jacob, Wyatt, Emily A., Shi, Catherine, Shatz, Whitney, Hass, Philip E., Mathieu, Mary, Yi, Li, Corn, Jacob E., Maass, Katie F., Wang, Kathryn, Dion, Michelle Z., Andersen, Nisana, Loyet, Kelly M., van Lookeren Campagne, Menno, Rajagopal, Karthikan, Dickmann, Leslie, Scheer, Justin M., Kelley, Robert F.
Publicado 2017

An adapted consensus protein design strategy for identifying globally optimal biotherapeutics

por Liu, Yanyun, Tsang, Kenny, Mays, Michelle, Hansen, Gale, Chiecko, Jeffrey, Crames, Maureen, Wei, Yangjie, Zhou, Weijie, Fredrick, Chase, Hu, James, Liu, Dongmei, Gebhard, Douglas, Huang, Zhong-Fu, Datar, Akshita, Kronkaitis, Anthony, Gueneva-Boucheva, Kristina, Seeliger, Daniel, Han, Fei, Sen, Saurabh, Kasturirangan, Srinath, Scheer, Justin M., Nixon, Andrew E., Panavas, Tadas, Marlow, Michael S., Kumar, Sandeep
Publicado 2022