Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor

por Kleinau, Gunnar, Heyder, Nicolas A., Tao, Ya-Xiong, Scheerer, Patrick
Publicado 2020

Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83

por Müller, Anne, Berkmann, Julia Catherine, Scheerer, Patrick, Biebermann, Heike, Kleinau, Gunnar
Publicado 2016

SAT026 Melanocortin Receptors In The Earliest Chordates?

por Ji, Ren-Lei, Jiang, Shanshan, Kleinau, Gunnar, Scheerer, Patrick, Tao, Ya-Xiong
Publicado 2023

Binding, Thermodynamics, and Selectivity of a Non-peptide Antagonist to the Melanocortin-4 Receptor

por Saleh, Noureldin, Kleinau, Gunnar, Heyder, Nicolas, Clark, Timothy, Hildebrand, Peter W., Scheerer, Patrick
Publicado 2018

Is the Neuropeptide PEN a Ligand of GPR83?

por Giesecke, Yvonne, Asimi, Vahid, Stulberg, Valentina, Kleinau, Gunnar, Scheerer, Patrick, Koksch, Beate, Grötzinger, Carsten
Publicado 2023

Role of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction

por Rose, Alexander S., Zachariae, Ulrich, Grubmüller, Helmut, Hofmann, Klaus Peter, Scheerer, Patrick, Hildebrand, Peter W.
Publicado 2015

Phytochromes in Agrobacterium fabrum

por Lamparter, Tilman, Xue, Peng, Elkurdi, Afaf, Kaeser, Gero, Sauthof, Luisa, Scheerer, Patrick, Krauß, Norbert
Publicado 2021

Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting

por Speck, David, Kleinau, Gunnar, Szczepek, Michal, Kwiatkowski, Dennis, Catar, Rusan, Philippe, Aurélie, Scheerer, Patrick
Publicado 2022

Structural–Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work

por Kleinau, Gunnar, Worth, Catherine L., Kreuchwig, Annika, Biebermann, Heike, Marcinkowski, Patrick, Scheerer, Patrick, Krause, Gerd
Publicado 2017

Melanocortin Receptor Accessory Protein 2-Induced Adrenocorticotropic Hormone Response of Human Melanocortin 4 Receptor

por Soletto, Lucia, Hernández-Balfagó, Sergio, Rocha, Ana, Scheerer, Patrick, Kleinau, Gunnar, Cerdá-Reverter, José Miguel
Publicado 2018

Key Amino Acids in the Bacterial (6-4) Photolyase PhrB from Agrobacterium fabrum

por Graf, Dominik, Wesslowski, Janine, Ma, Hongju, Scheerer, Patrick, Krauß, Norbert, Oberpichler, Inga, Zhang, Fan, Lamparter, Tilman
Publicado 2015

The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR

por Kalveram, Laura, Kleinau, Gunnar, Szymańska, Kamila, Scheerer, Patrick, Rivero-Müller, Adolfo, Grüters-Kieslich, Annette, Biebermann, Heike
Publicado 2019

Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants

por Speck, David, Kleinau, Gunnar, Meininghaus, Mark, Erbe, Antje, Einfeldt, Alexandra, Szczepek, Michal, Scheerer, Patrick, Pütter, Vera
Publicado 2022

A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation

por Reininghaus, Nanina, Paisdzior, Sarah, Höpfner, Friederike, Jyrch, Sabine, Cetindag, Cigdem, Scheerer, Patrick, Kühnen, Peter, Biebermann, Heike
Publicado 2022

Evaluation of Pharmacological Rescue of Melanocortin-4 Receptor Nonsense Mutations by Aminoglycoside

por Höpfner, Friederike, Paisdzior, Sarah, Reininghaus, Nanina, Sohail, Iqra, Scheerer, Patrick, Annibale, Paolo, Biebermann, Heike, Kühnen, Peter
Publicado 2022

Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6

por Qureshi, Bilal M., Schmidt, Andrea, Behrmann, Elmar, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Heck, Martin, Scheerer, Patrick
Publicado 2018

Phytochrome Mediated Responses in Agrobacterium fabrum: Growth, Motility and Plant Infection

por Xue, Peng, Bai, Yingnan, Rottwinkel, Gregor, Averbukh, Elizaveta, Ma, Yuanyuan, Roeder, Thomas, Scheerer, Patrick, Krauß, Norbert, Lamparter, Tilman
Publicado 2021

Functional modulation of PTH1R activation and signaling by RAMP2

por Nemec, Katarina, Schihada, Hannes, Kleinau, Gunnar, Zabel, Ulrike, Grushevskyi, Eugene O., Scheerer, Patrick, Lohse, Martin J., Maiellaro, Isabella
Publicado 2022

The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor

por Bräunig, Julia, Dinter, Juliane, Höfig, Carolin S., Paisdzior, Sarah, Szczepek, Michal, Scheerer, Patrick, Rosowski, Mark, Mittag, Jens, Kleinau, Gunnar, Biebermann, Heike
Publicado 2018

Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules

por Schulze, Amadeus Samuel, Kleinau, Gunnar, Krakowsky, Rosanna, Rochmann, David, Das, Ranajit, Worth, Catherine L., Krumbholz, Petra, Scheerer, Patrick, Stäubert, Claudia
Publicado 2022