A Grand Challenge in Aging Interventions: From Mice to Humans

por Scheibye-Knudsen, Morten
Publicado 2020

Tracking the dynamics of cellular senescence

por Heckenbach, Indra, Scheibye-Knudsen, Morten
Publicado 2023

MitophAging: Mitophagy in Aging and Disease

por Bakula, Daniela, Scheibye-Knudsen, Morten
Publicado 2020

Clinical Trials Targeting Aging

por Nielsen, Johannes Leth, Bakula, Daniela, Scheibye-Knudsen, Morten
Publicado 2022

A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging

por Scheibye-Knudsen, Morten, Scheibye-Alsing, Karsten, Canugovi, Chandrika, Croteau, Deborah L., Bohr, Vilhelm A.
Publicado 2013

Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

por Keijzers, Guido, Bakula, Daniela, Petr, Michael Angelo, Madsen, Nils Gedsig Kirkelund, Teklu, Amanuel, Mkrtchyan, Garik, Osborne, Brenna, Scheibye-Knudsen, Morten
Publicado 2018

High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

por Mkrtchyan, Garik V., Veviorskiy, Alexander, Izumchenko, Evgeny, Shneyderman, Anastasia, Pun, Frank W., Ozerov, Ivan V., Aliper, Alex, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Publicado 2022

Histone malonylation is regulated by SIRT5 and KAT2A

por Zhang, Ran, Bons, Joanna, Scheidemantle, Grace, Liu, Xiaojing, Bielska, Olga, Carrico, Chris, Rose, Jacob, Heckenbach, Indra, Scheibye-Knudsen, Morten, Schilling, Birgit, Verdin, Eric
Publicado 2023

Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers

por Mamoshina, Polina, Kochetov, Kirill, Cortese, Franco, Kovalchuk, Anna, Aliper, Alexander, Putin, Evgeny, Scheibye-Knudsen, Morten, Cantor, Charles R., Skjodt, Neil M., Kovalchuk, Olga, Zhavoronkov, Alex
Publicado 2019

Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

por Li, Xiaolin, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Cui, Honghua, Qiu, Lu, Li, Jian, He, Yuping, Huang, Jing, Bohr, Vilhelm A., Ng, Tzi Bun, Guo, Hongwei
Publicado 2014

CNOT6: A Novel Regulator of DNA Mismatch Repair

por Song, Peng, Liu, Shaojun, Liu, Dekang, Keijzers, Guido, Bakula, Daniela, Duan, Shunlei, de Wind, Niels, Ye, Zilu, Vakhrushev, Sergey Y., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel
Publicado 2022

Population Specific Biomarkers of Human Aging: A Big Data Study Using South Korean, Canadian, and Eastern European Patient Populations

por Mamoshina, Polina, Kochetov, Kirill, Putin, Evgeny, Cortese, Franco, Aliper, Alexander, Lee, Won-Suk, Ahn, Sung-Min, Uhn, Lee, Skjodt, Neil, Kovalchuk, Olga, Scheibye-Knudsen, Morten, Zhavoronkov, Alex
Publicado 2018

EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

por Durhuus, Jon Ambæk, Rozing, Maarten P., Nielsen, Marie Krogh, Molbech, Christopher Rue, Keijzers, Guido, Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi G. J., Sørensen, Torben Lykke
Publicado 2021

A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

por Boutoual, Rachid, Jo, Hyunsun, Heckenbach, Indra, Tiwari, Ritesh, Kasler, Herbert, Lerner, Chad A., Shah, Samah, Schilling, Birgit, Calvanese, Vincenzo, Rardin, Matthew J., Scheibye-Knudsen, Morten, Verdin, Eric
Publicado 2022

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β(2) adrenergic agonist

por Wnorowski, Artur, Dudzik, Danuta, Bernier, Michel, Wójcik, Jakub, Keijzers, Guido, Diaz-Ruiz, Alberto, Mazur, Karolina, Zhang, Yongqing, Han, Haiyong, Scheibye-Knudsen, Morten, Jozwiak, Krzysztof, Barbas, Coral, Wainer, Irving W.
Publicado 2022

Long-Term Artificial Sweetener Acesulfame Potassium Treatment Alters Neurometabolic Functions in C57BL/6J Mice

por Cong, Wei-na, Wang, Rui, Cai, Huan, Daimon, Caitlin M., Scheibye-Knudsen, Morten, Bohr, Vilhelm A., Turkin, Rebecca, Wood, William H., Becker, Kevin G., Moaddel, Ruin, Maudsley, Stuart, Martin, Bronwen
Publicado 2013

Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

por Scheibye-Knudsen, Morten, Ramamoorthy, Mahesh, Sykora, Peter, Maynard, Scott, Lin, Ping-Chang, Minor, Robin K., Wilson III, David M., Cooper, Marcus, Spencer, Richard, de Cabo, Rafael, Croteau, Deborah L., Bohr, Vilhelm A.
Publicado 2012

A research agenda for aging in China in the 21st century

por Fang, Evandro Fei, Scheibye-Knudsen, Morten, Jahn, Heiko J., Li, Juan, Ling, Li, Guo, Hongwei, Zhu, Xinqiang, Preedy, Victor, Lu, Huiming, Bohr, Vilhelm A., Chan, Wai Yee, Liu, Yuanli, Ng, Tzi Bun
Publicado 2015

Nuclear morphology is a deep learning biomarker of cellular senescence

por Heckenbach, Indra, Mkrtchyan, Garik V., Ezra, Michael Ben, Bakula, Daniela, Madsen, Jakob Sture, Nielsen, Malte Hasle, Oró, Denise, Osborne, Brenna, Covarrubias, Anthony J, Idda, M. Laura, Gorospe, Myriam, Mortensen, Laust, Verdin, Eric, Westendorp, Rudi, Scheibye-Knudsen, Morten
Publicado 2022

Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity

por McIntyre, Rebecca L., Denis, Simone W., Kamble, Rashmi, Molenaars, Marte, Petr, Michael, Schomakers, Bauke V., Rahman, Mizanur, Gupta, Siddhartha, Toth, Marton L., Vanapalli, Siva A., Jongejan, Aldo, Scheibye‐Knudsen, Morten, Houtkooper, Riekelt H., Janssens, Georges E.
Publicado 2021