A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use

por Ardisasmita, Arif Ibrahim, Schene, Imre F., Joore, Indi P., Kok, Gautam, Hendriks, Delilah, Artegiani, Benedetta, Mokry, Michal, Nieuwenhuis, Edward E. S., Fuchs, Sabine A.
Publicado 2022

Misdiagnosis of CTX due to propofol: The interference of total intravenous propofol anaesthesia with bile acid profiling

por Claesen, Joep L. A., Koomen, Erik, Schene, Imre F., Jans, Judith J. M., Mast, Natalia, Pikuleva, Irina A., van der Ham, Maria, de Sain‐van der Velden, Monique G. M., Fuchs, Sabine A.
Publicado 2020

Prime editing for functional repair in patient-derived disease models

por Schene, Imre F., Joore, Indi P., Oka, Rurika, Mokry, Michal, van Vugt, Anke H. M., van Boxtel, Ruben, van der Doef, Hubert P. J., van der Laan, Luc J. W., Verstegen, Monique M. A., van Hasselt, Peter M., Nieuwenhuis, Edward E. S., Fuchs, Sabine A.
Publicado 2020

The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism

por Lehmann, Vivian, Schene, Imre F., Ardisasmita, Arif I., Liv, Nalan, Veenendaal, Tineke, Klumperman, Judith, van der Doef, Hubert P. J., Verkade, Henkjan J., Verstegen, Monique M. A., van der Laan, Luc J. W., Jans, Judith J. M., Verhoeven‐Duif, Nanda M., van Hasselt, Peter M., Nieuwenhuis, Edward E. S., Spee, Bart, Fuchs, Sabine A.
Publicado 2021

Aminoacyl-tRNA synthetase deficiencies in search of common themes

por Fuchs, Sabine A., Schene, Imre F., Kok, Gautam, Jansen, Jurriaan M., Nikkels, Peter G. J., van Gassen, Koen L. I., Terheggen-Lagro, Suzanne W. J., van der Crabben, Saskia N., Hoeks, Sanne E., Niers, Laetitia E. M., Wolf, Nicole I., de Vries, Maaike C., Koolen, David A., Houwen, Roderick H. J., Mulder, Margot F., van Hasselt, Peter M.
Publicado 2018

Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells

por Schneeberger, Kerstin, Sánchez‐Romero, Natalia, Ye, Shicheng, van Steenbeek, Frank G., Oosterhoff, Loes A., Pla Palacin, Iris, Chen, Chen, van Wolferen, Monique E., van Tienderen, Gilles, Lieshout, Ruby, Colemonts‐Vroninks, Haaike, Schene, Imre, Hoekstra, Ruurdtje, Verstegen, Monique M.A., van der Laan, Luc J.W., Penning, Louis C., Fuchs, Sabine A., Clevers, Hans, De Kock, Joery, Baptista, Pedro M., Spee, Bart
Publicado 2020

Treatment of ARS deficiencies with specific amino acids

por Kok, Gautam, Tseng, Laura, Schene, Imre F., Dijsselhof, Monique E., Salomons, Gajja, Mendes, Marisa I., Smith, Desiree E. C., Wiedemann, Arnaud, Canton, Marie, Feillet, François, de Koning, Tom J., Boothe, Megan, Dean, Joy, Kassel, Rachel, Ferreira, Elise A., van den Born, Margreet, Nieuwenhuis, Edward E. S., Rehmann, Holger, Terheggen-Lagro, Suzanne W. J., van Karnebeek, Clara D. M., Fuchs, Sabine A.
Publicado 2021

Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease

por Verstegen, Monique M. A., Roos, Floris J. M., Burka, Ksenia, Gehart, Helmuth, Jager, Myrthe, de Wolf, Maaike, Bijvelds, Marcel J. C., de Jonge, Hugo R., Ardisasmita, Arif I., van Huizen, Nick A., Roest, Henk P., de Jonge, Jeroen, Koch, Michael, Pampaloni, Francesco, Fuchs, Sabine A., Schene, Imre F., Luider, Theo M., van der Doef, Hubert P. J., Bodewes, Frank A. J. A., de Kleine, Ruben H. J., Spee, Bart, Kremers, Gert-Jan, Clevers, Hans, IJzermans, Jan N. M., Cuppen, Edwin, van der Laan, Luc J. W.
Publicado 2020