Acute Effects of Focused Ultrasound-Induced Blood-Brain Barrier Opening on Anti-Pyroglu3 Abeta Antibody Delivery and Immune Responses

por Bathini, Praveen, Sun, Tao, Schenk, Mathias, Schilling, Stephan, McDannold, Nathan J., Lemere, Cynthia A.
Publicado 2022

Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mi...

por Hoffmann, Torsten, Rahfeld, Jens-Ulrich, Schenk, Mathias, Ponath, Falk, Makioka, Koki, Hutter-Paier, Birgit, Lues, Inge, Lemere, Cynthia A., Schilling, Stephan
Publicado 2021

Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions

por Jansig, Edith, Geissler, Stefanie, Rieckmann, Vera, Kuenemund, Anja, Hietel, Benjamin, Schenk, Mathias, Wussow, Sebastian, Kreideweiss, Patrick, Panzner, Steffen, Reinsch, Christian, Cynis, Holger
Publicado 2020

Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology

por Gnoth, Kathrin, Piechotta, Anke, Kleinschmidt, Martin, Konrath, Sandra, Schenk, Mathias, Taudte, Nadine, Ramsbeck, Daniel, Rieckmann, Vera, Geissler, Stefanie, Eichentopf, Rico, Barendrecht, Susan, Hartlage-Rübsamen, Maike, Demuth, Hans-Ulrich, Roßner, Steffen, Cynis, Holger, Rahfeld, Jens-Ulrich, Schilling, Stephan
Publicado 2020

A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies

por Hartlage-Rübsamen, Maike, Bluhm, Alexandra, Moceri, Sandra, Machner, Lisa, Köppen, Janett, Schenk, Mathias, Hilbrich, Isabel, Holzer, Max, Weidenfeller, Martin, Richter, Franziska, Coras, Roland, Serrano, Geidy E., Beach, Thomas G., Schilling, Stephan, von Hörsten, Stephan, Xiang, Wei, Schulze, Anja, Roßner, Steffen
Publicado 2021

Electrostatic anti-CD33-antibody–protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia

por Bäumer, Nicole, Scheller, Annika, Wittmann, Lisa, Faust, Andreas, Apel, Mara, Nimmagadda, Subbaiah Chary, Geyer, Christiane, Grunert, Katharina, Kellmann, Neele, Peipp, Matthias, Kailayangiri, Sareetha, Gutierrez Suburu, Matias Ezequiel, Strassert, Cristian A., Schenk, Mathias, Greune, Lilo, Rüter, Christian, Dersch, Petra, Hartmann, Wolfgang, Rossig, Claudia, Neri, Dario, Müller-Tidow, Carsten, Schwöppe, Christian, Schliemann, Christoph, Khandanpour, Cyrus, Lenz, Georg, Berdel, Wolfgang E., Bäumer, Sebastian
Publicado 2022