Lessons from the SWITCH trial: changing glucocorticoids in the management of metastatic castration-resistant prostate cancer (mCRPC)

por Teo, Min Yuen, Scher, Howard I.
Publicado 2018

Prevalence of Prostate Cancer Clinical States and Mortality in the United States: Estimates Using a Dynamic Progression Model

por Scher, Howard I., Solo, Kirk, Valant, Jason, Todd, Mary B., Mehra, Maneesha
Publicado 2015

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling

por Rajasekhar, Vinagolu K., Studer, Lorenz, Gerald, William, Socci, Nicholas D., Scher, Howard I.
Publicado 2011

Phase II trial of SM-88, a cancer metabolism based therapy, in non-metastatic biochemical recurrent prostate cancer

por Gartrell, Benjamin A., Roach, Mack, Retter, Avi, Sokol, Gerald H., Del Priore, Giuseppe, Scher, Howard I.
Publicado 2020

Optimal Strategy and Benefit of Pulsed Therapy Depend On Tumor Heterogeneity and Aggressiveness at Time of Treatment Initiation

por Mathur, Deepti, Taylor, Bradford P., Chatila, Walid K., Scher, Howard I., Schultz, Nikolaus, Razavi, Pedram, Xavier, Joao B.
Publicado 2022

Impact of clinical versus radiographic progression on clinical outcomes in metastatic castration-resistant prostate cancer

por Rao, Arpit, Scher, Howard I, De Porre, Peter, Yu, Margaret K, Londhe, Anil, Qi, Keqin, Morris, Michael J, Ryan, Charles
Publicado 2020

Treatment with a GnRH receptor agonist, but not the GnRH receptor antagonist degarelix, induces atherosclerotic plaque instability in ApoE(−/−) mice

por Knutsson, Anki, Hsiung, Sabrina, Celik, Selvi, Rattik, Sara, Mattisson, Ingrid Yao, Wigren, Maria, Scher, Howard I., Nilsson, Jan, Hultgårdh-Nilsson, Anna
Publicado 2016

Automated Bone Scan Index to Optimize Prostate Cancer Working Group Radiographic Progression Criteria for Men With Metastatic Castration-Resistant Prostate Cancer

por Anand, Aseem, Heller, Glenn, Fox, Joseph, Danila, Daniel C., Bjartell, Anders, Edenbrandt, Lars, Larson, Steven M., Scher, Howard I., Morris, Michael J.
Publicado 2022

Clinical outcomes and survival surrogacy studies of prostate‐specific antigen declines following enzalutamide in men with metastatic castration‐resistant prostate cancer previously...

por Armstrong, Andrew J., Saad, Fred, Phung, De, Dmuchowski, Carl, Shore, Neal D., Fizazi, Karim, Hirmand, Mohammad, Forer, David, Scher, Howard I., Bono, Johann De
Publicado 2017

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice

por Philp, Lisa K., Day, Tanya K., Butler, Miriam S., Laven-Law, Geraldine, Jindal, Shalini, Hickey, Theresa E., Scher, Howard I., Butler, Lisa M., Tilley, Wayne D.
Publicado 2016

Development of an immunofluorescent AR-V7 circulating tumor cell assay – A blood-based test for men with metastatic prostate cancer

por Lu, David, Krupa, Rachel, Harvey, Melissa, Graf, Ryon P., Schreiber, Nicole, Barnett, Ethan, Carbone, Emily, Jendrisak, Adam, Gill, Audrey, Orr, Sarah, Scher, Howard I., Schonhoft, Joseph D.
Publicado 2020

The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide: A Multivariate Analysis of the Phase III AFFIRM Trial

por Zhao, Jimmy L., Fizazi, Karim, Saad, Fred, Chi, Kim N., Taplin, Mary-Ellen, Sternberg, Cora N., Armstrong, Andrew J., de Bono, Johann S., Duggan, William T., Scher, Howard I.
Publicado 2022

Population pharmacokinetic analysis of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in adult patients with solid tumors

por Aregbe, Abdulateef O., Sherer, Eric A., Egorin, Merrill J., Scher, Howard I., Solit, David B., Ramanathan, Ramesh K., Ramalingam, Suresh, Belani, Chandra P., Ivy, Percy S., Bies, Robert R.
Publicado 2012

Association Between New Unconfirmed Bone Lesions and Outcomes in Men With Metastatic Castration-Resistant Prostate Cancer Treated With Enzalutamide: Secondary Analysis of the PREVA...

por Armstrong, Andrew J., Al-Adhami, Mohammed, Lin, Ping, Parli, Teresa, Sugg, Jennifer, Steinberg, Joyce, Tombal, Bertrand, Sternberg, Cora N., de Bono, Johann, Scher, Howard I., Beer, Tomasz M.
Publicado 2019

Harnessing Naturally Occurring Tumor Immunity: A Clinical Vaccine Trial in Prostate Cancer

por Frank, Mayu O., Kaufman, Julia, Tian, Suyan, Suárez-Fariñas, Mayte, Parveen, Salina, Blachère, Nathalie E., Morris, Michael J., Slovin, Susan, Scher, Howard I., Albert, Matthew L., Darnell, Robert B.
Publicado 2010

ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss

por Chen, Yu, Chi, Ping, Rockowitz, Shira, Iaquinta, Phillip J., Shamu, Tambudzai, Shukla, Shipra, Gao, Dong, Sirota, Inna, Carver, Brett S., Wongvipat, John, Scher, Howard I., Zheng, Deyou, Sawyers, Charles L.
Publicado 2013

Identification of novel androgen receptor target genes in prostate cancer

por Jariwala, Unnati, Prescott, Jennifer, Jia, Li, Barski, Artem, Pregizer, Steve, Cogan, Jon P, Arasheben, Armin, Tilley, Wayne D, Scher, Howard I, Gerald, William L, Buchanan, Grant, Coetzee, Gerhard A, Frenkel, Baruch
Publicado 2007

Enzalutamide in European and North American men participating in the AFFIRM trial

por Merseburger, Axel S, Scher, Howard I, Bellmunt, Joaquim, Miller, Kurt, Mulders, Peter FA, Stenzl, Arnulf, Sternberg, Cora N, Fizazi, Karim, Hirmand, Mohammad, Franks, Billy, Haas, Gabriel P, de Bono, Johann, de Wit, Ronald
Publicado 2015

Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors

por Pandit-Taskar, Neeta, O’Donoghue, Joseph A, Divgi, Chaitanya R, Wills, Eze A, Schwartz, Lawrence, Gönen, Mithat, Smith-Jones, Peter, Bander, Neil H, Scher, Howard I, Larson, Steven M, Morris, Michael J
Publicado 2015

Statin and metformin use and outcomes in patients with castration-resistant prostate cancer treated with enzalutamide: A meta-analysis of AFFIRM, PREVAIL and PROSPER

por Joshua, Anthony M., Armstrong, Andrew, Crumbaker, Megan, Scher, Howard I., de Bono, Johann, Tombal, Bertrand, Hussain, Maha, Sternberg, Cora N., Gillessen, Silke, Carles, Joan, Fizazi, Karim, Lin, Ping, Duggan, William, Sugg, Jennifer, Russell, David, Beer, Tomasz M.
Publicado 2022