Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase

por Maetani, Micah, Kato, Nobutaka, Jabor, Valquiria A. P., Calil, Felipe A., Nonato, Maria Cristina, Scherer, Christina A., Schreiber, Stuart L.
Publicado 2017

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intrac...

por Nühs, Andrea, De Rycker, Manu, Manthri, Sujatha, Comer, Eamon, Scherer, Christina A., Schreiber, Stuart L., Ioset, Jean-Robert, Gray, David W.
Publicado 2015

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

por Weïwer, Michel, Spoonamore, James, Wei, Jingqiang, Guichard, Boris, Ross, Nathan T., Masson, Kristina, Silkworth, Whitney, Dandapani, Sivaraman, Palmer, Michelle, Scherer, Christina A., Stern, Andrew M., Schreiber, Stuart L., Munoz, Benito
Publicado 2012

Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human

por Magness, Charles L, Fellin, P Campion, Thomas, Matthew J, Korth, Marcus J, Agy, Michael B, Proll, Sean C, Fitzgibbon, Matthew, Scherer, Christina A, Miner, Douglas G, Katze, Michael G, Iadonato, Shawn P
Publicado 2005

Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors

por Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.
Publicado 2015

High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria

por Swann, Justine, Corey, Victoria, Scherer, Christina A., Kato, Nobutaka, Comer, Eamon, Maetani, Micah, Antonova-Koch, Yevgeniya, Reimer, Christin, Gagaring, Kerstin, Ibanez, Maureen, Plouffe, David, Zeeman, Anne-Marie, Kocken, Clemens H. M., McNamara, Case W., Schreiber, Stuart L., Campo, Brice, Winzeler, Elizabeth A., Meister, Stephan
Publicado 2016

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission

por Plouffe, David M., Wree, Melanie, Du, Alan Y., Meister, Stephan, Li, Fengwu, Patra, Kailash, Lubar, Aristea, Okitsu, Shinji L., Flannery, Erika L., Kato, Nobutaka, Tanaseichuk, Olga, Comer, Eamon, Zhou, Bin, Kuhen, Kelli, Zhou, Yingyao, Leroy, Didier, Schreiber, Stuart L., Scherer, Christina A., Vinetz, Joseph, Winzeler, Elizabeth A.
Publicado 2016

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents

por Comer, Eamon, Beaudoin, Jennifer A., Kato, Nobutaka, Fitzgerald, Mark E., Heidebrecht, Richard W., Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E., Lukens, Amanda K., Wiegand, Roger C., Wirth, Dyann F., Palmer, Michelle A., Foley, Michael A., Munoz, Benito, Scherer, Christina A., Duvall, Jeremy R., Schreiber, Stuart L.
Publicado 2014