Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)

por van der Sligte, Naomi E, Scherpen, Frank J G, ter Elst, Arja, Guryev, Victor, van Leeuwen, Frank N, de Bont, Eveline S J M
Publicado 2015

Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

por Mahmud, Hasan, Kornblau, Steven M., ter Elst, Arja, Scherpen, Frank J. G., Qiu, Yi Hua, Coombes, Kevin R., de Bont, Eveline S. J. M.
Publicado 2016

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML

por Mahmud, Hasan, Scherpen, Frank J.G., de Boer, Tiny Meeuwsen, Lourens, Harm-Jan, Schoenherr, Caroline, Eder, Matthias, Scherr, Michaela, Guryev, Victor, De Bont, Eveline S.
Publicado 2017

The Presence of EGFR T790M in TKI-Naïve Lung Cancer Samples of Patients Who Developed a T790M-Positive Relapse on First or Second Generation TKI Is Rare

por Li, Weiting, Kok, Klaas, Tan, Geok Wee, Meng, Pei, Mastik, Mirjam, Rifaela, Naomi, Scherpen, Frank, Hiltermann, T. Jeroen N., Groen, Harry J. M., van der Wekken, Anthonie J., van den Berg, Anke
Publicado 2022

Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair

por Mahmud, Hasan, ter Elst, Arja, Scherpen, Frank J.G., Boer, Tiny Meeuwsen-de, Kampen, Kim R., de Haas, Valérie, Guryev, Victor, Peppelenbosch, Maikel M., Kornblau, Steven M., de Bont, Eveline S.J.M.
Publicado 2019

Growth-Factor-Driven Rescue to Receptor Tyrosine Kinase (RTK) Inhibitors through Akt and Erk Phosphorylation in Pediatric Low Grade Astrocytoma and Ependymoma

por Sie, Mariska, den Dunnen, Wilfred F. A., Lourens, Harm Jan, Meeuwsen-de Boer, Tiny G. J., Scherpen, Frank J. G., Zomerman, Walderik W., Kampen, Kim R., Hoving, Eelco W., de Bont, Eveline S. J. M.
Publicado 2015

Essential role for cyclic-AMP responsive element binding protein 1 (CREB) in the survival of acute lymphoblastic leukemia

por van der Sligte, Naomi E., Kampen, Kim R., ter Elst, Arja, Scherpen, Frank J.G., Meeuwsen-de Boer, Tiny G.J., Guryev, Victor, van Leeuwen, Frank N., Kornblau, Steven M., de Bont, Eveline S.J.M.
Publicado 2015

CREB signaling activity correlates with differentiation and survival in medulloblastoma

por Armandari, Inna, Zomerman, Walderik W., Plasschaert, Sabine L. A., Smit, Marlinde J., Martini, Tosca. E. I., de Camargo Magalhães, Eduardo S., Hogeling, Shanna M., Rozema-Huizinga, Geesina C., Lourens, Harm J., Meeuwsen-de Boer, Tiny G. J., Scherpen, Frank J. G., de Bont, Eveline S. J. M., Bruggeman, Sophia W. M.
Publicado 2021

Clinical Value of EGFR Copy Number Gain Determined by Amplicon-Based Targeted Next Generation Sequencing in Patients with EGFR-Mutated NSCLC

por Wei, Jiacong, Meng, Pei, Terpstra, Miente Martijn, van Rijk, Anke, Tamminga, Menno, Scherpen, Frank, ter Elst, Arja, Alimohamed, Mohamed Z., Johansson, Lennart F., Stigt, Jos, Gijtenbeek, Rolof P. G., van Putten, John, Hiltermann, T. Jeroen N., Groen, Harry J. M., Kok, Klaas, van der Wekken, Anthonie J., van den Berg, Anke
Publicado 2021

The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity

por Smit, Marlinde J., Martini, Tosca E. I., Armandari, Inna, Bočkaj, Irena, Zomerman, Walderik W., de Camargo Magalhães, Eduardo S., Siragna, Zillah, Meeuwsen, Tiny G. J., Scherpen, Frank J. G., Schoots, Mirthe H., Ritsema, Martha, den Dunnen, Wilfred F. A., Hoving, Eelco W., Paridaen, Judith T. M. L., de Haan, Gerald, Guryev, Victor, Bruggeman, Sophia W. M.
Publicado 2022