Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data

por Lenk, Lennart, Alsadeq, Ameera, Schewe, Denis M.
Publicado 2020

Perspectives of Fc engineered antibodies in CD19 targeting immunotherapies in pediatric B-cell precursor acute lymphoblastic leukemia

por Kellner, Christian, Peipp, Matthias, Gramatzki, Martin, Schrappe, Martin, Schewe, Denis M.
Publicado 2018

Perspectives of targeting LILRB1 in innate and adaptive immune checkpoint therapy of cancer

por Zeller, Tobias, Münnich, Ira A., Windisch, Roland, Hilger, Patricia, Schewe, Denis M., Humpe, Andreas, Kellner, Christian
Publicado 2023

TGFβ2 dictates disseminated tumour cell fate in target organs through TGFβ-RIII and p38α/β signalling

por Bragado, Paloma, Estrada, Yeriel, Parikh, Falguni, Krause, Sarah, Capobianco, Carla, Farina, Hernan G., Schewe, Denis M, Aguirre-Ghiso, Julio A.
Publicado 2013

Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment

por Adomako, Alfred, Calvo, Veronica, Biran, Noa, Osman, Keren, Chari, Ajai, Paton, James C, Paton, Adrienne W, Moore, Kateri, Schewe, Denis M, Aguirre-Ghiso, Julio A
Publicado 2015

Accumulation of T-cell-suppressive PD-L1(high) extracellular vesicles is associated with GvHD and might impact GvL efficacy

por Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios
Publicado 2023

Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab

por Baumann, Niklas, Arndt, Christian, Petersen, Judith, Lustig, Marta, Rösner, Thies, Klausz, Katja, Kellner, Christian, Bultmann, Miriam, Bastian, Lorenz, Vogiatzi, Fotini, Leusen, Jeanette H. W., Burger, Renate, Schewe, Denis M., Peipp, Matthias, Valerius, Thomas
Publicado 2022

AP-1 Transcription Factor Complex Members FOSB and FOS are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL

por Spory, Lea, Zimmermann, Johannes, Vossen-Gajcy, Michaela, Beder, Thomas, Bastian, Lorenz, Alsadeq, Ameera, Winterberg, Dorothee, Vogiatzi, Fotini, Wirbelauer, Tim, Bhat, Hilal, Borkhardt, Arndt, Bhatia, Sanil, Schrappe, Martin, Cario, Gunnar, Schewe, Denis M., Lenk, Lennart
Publicado 2023

Molecular complete remission following combination treatment of daratumumab and venetoclax in an adolescent with relapsed mixed phenotype acute leukemia

por Stanulla, Martin, Schewe, Denis M., Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Eberl, Wolfgang, Wolf, Saskia, Wolf, Julian, Vogiatzi, Fotini, Bergmann, Anke K., Cario, Gunnar, Beier, Rita, Sauer, Martin, Kratz, Christian P., Maecker-Kolhoff, Britta
Publicado 2023

Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions

por Baumann, Niklas, Rösner, Thies, Jansen, J. H. Marco, Chan, Chilam, Marie Eichholz, Klara, Klausz, Katja, Winterberg, Dorothee, Müller, Kristina, Humpe, Andreas, Burger, Renate, Peipp, Matthias, Schewe, Denis M., Kellner, Christian, Leusen, Jeanette H. W., Valerius, Thomas
Publicado 2021

Outcome for Pediatric Adreno-Cortical Tumors Is Best Predicted by the COG Stage and Five-Item Microscopic Score—Report from the German MET Studies

por Kuhlen, Michaela, Kunstreich, Marina, Wudy, Stefan A., Holterhus, Paul-Martin, Lessel, Lienhard, Schneider, Dominik T., Brecht, Ines B., Schewe, Denis M., Seitz, Guido, Roecken, Christoph, Vokuhl, Christian, Johann, Pascal D., Frühwald, Michael C., Vorwerk, Peter, Redlich, Antje
Publicado 2022

Recurrent DNMT3B rearrangements are associated with unfavorable outcome in dicentric (9;20)-positive pediatric BCP-ALL

por Antić, Željko, van Bömmel, Alena, Riege, Konstantin, Lentes, Jana, Schröder, Charlotte, Alten, Julia, Eckert, Cornelia, Fuhrmann, Lara, Steinemann, Doris, Lenk, Lennart, Schewe, Denis M., Zimmermann, Martin, Schrappe, Martin, Schlegelberger, Brigitte, Cario, Gunnar, Hoffmann, Steve, Bergmann, Anke K.
Publicado 2023

Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia

por Abdelrasoul, Hend, Vadakumchery, Anila, Werner, Markus, Lenk, Lennart, Khadour, Ahmad, Young, Marc, El Ayoubi, Omar, Vogiatzi, Fotini, Krämer, Markus, Schmid, Vera, Chen, Zhengshan, Yousafzai, Yasar, Cario, Gunnar, Schrappe, Martin, Müschen, Markus, Halsey, Christina, Mulaw, Medhanie A., Schewe, Denis M., Hobeika, Elias, Alsadeq, Ameera, Jumaa, Hassan
Publicado 2020

Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia

por Lenk, Lennart, Winterberg, Dorothee, Vogiatzi, Fotini, Laqua, Anna, Spory, Lea, Mayar, Ahmad, Dietterle, Anna, Münch, Gina, Vokuhl, Christian, Richter, Julia, Polson, Andrew G., Schüler, Thomas, Kahlert, Ulf D., Peipp, Matthias, Valerius, Thomas, Schrappe, Martin, Cario, Gunnar, Jumaa, Hassan, Hobeika, Elias, Brüggemann, Monika, Alsadeq, Ameera, Schewe, Denis M.
Publicado 2022

Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages

por Zeller, Tobias, Lutz, Sebastian, Münnich, Ira A., Windisch, Roland, Hilger, Patricia, Herold, Tobias, Tahiri, Natyra, Banck, Jan C., Weigert, Oliver, Moosmann, Andreas, von Bergwelt-Baildon, Michael, Flamann, Cindy, Bruns, Heiko, Wichmann, Christian, Baumann, Niklas, Valerius, Thomas, Schewe, Denis M., Peipp, Matthias, Rösner, Thies, Humpe, Andreas, Kellner, Christian
Publicado 2022

CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia

por Lenk, Lennart, Carlet, Michela, Vogiatzi, Fotini, Spory, Lea, Winterberg, Dorothee, Cousins, Antony, Vossen-Gajcy, Michaela, Ibruli, Olta, Vokuhl, Christian, Cario, Gunnar, El Ayoubi, Omar, Kramer, Lisa, Ritgen, Matthias, Brüggemann, Monika, Häsler, Robert, Schrappe, Martin, Fuhrmann, Stephan, Halsey, Christina, Jeremias, Irmela, Hobeika, Elias, Jumaa, Hassan, Alsadeq, Ameera, Schewe, Denis M.
Publicado 2021

Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis

por Vogiatzi, Fotini, Heymann, Julia, Müller, Kristina, Winterberg, Dorothee, Drakul, Aneta, Rösner, Thies, Lenk, Lennart, Heib, Michelle, Gehlert, Carina Lynn, Cario, Gunnar, Schrappe, Martin, Claviez, Alexander, Bornhauser, Beat, Bourquin, Jean-Pierre, Bomken, Simon, Adam, Dieter, Frielitz, Fabian-Simon, Maecker-Kolhoff, Britta, Stanulla, Martin, Valerius, Thomas, Peipp, Matthias, Kellner, Christian, Schewe, Denis M.
Publicado 2022

In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets

por Carlet, Michela, Völse, Kerstin, Vergalli, Jenny, Becker, Martin, Herold, Tobias, Arner, Anja, Senft, Daniela, Jurinovic, Vindi, Liu, Wen-Hsin, Gao, Yuqiao, Dill, Veronika, Fehse, Boris, Baldus, Claudia D., Bastian, Lorenz, Lenk, Lennart, Schewe, Denis M., Bagnoli, Johannes W., Vick, Binje, Schmid, Jan Philipp, Wilhelm, Alexander, Marschalek, Rolf, Jost, Philipp J., Miething, Cornelius, Riecken, Kristoffer, Schmidt-Supprian, Marc, Binder, Vera, Jeremias, Irmela
Publicado 2021

MEDB-14. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome

por Kolodziejczak, Anna, Guerrini-Rousseau, Lea, Planchon, Julien Masliah, Ecker, Jonas, Selt, Florian, Mynarek, Martin, Obrecht, Denise, Sill, Martin, Hirsch, Steffen, Sturm, Dominik, Waszak, Sebastian M, Ramaswamy, Vijay, Pentikainen, Virve, Demir, Haci Ahmet, Clifford, Steven C, Schwalbe, Ed, Massimi, Luca, Snuderl, Matija, Galbraith, Kristyn, Karajannis, Matthias A, Hill, Katie, Li, Bryan, White, Christine L, Redmond, Shelagh, Loizos, Loizou, Jakob, Marcus, Kordes, Uwe, Schmid, Irene, Hauer, Julia, Blattmann, Claudia, Filippidou, Maria, Scheurlen, Wolfram, Kontny, Udo, Grund, Kerstin, Sutter, Christian, Pietsch, Torsten, van Tilburg, Cornelis M, Frank, Stephan, Schewe, Denis M, Malkin, David, Taylor, Michael D, Tabori, Uri, Bouffet, Eric, Kool, Marcel, Sahm, Felix, von Deimling, Andreas, Korshunov, Andrey, Von Hoff, Katja, Kratz, Christian, Jones, David T W, Rutkowski, Stefan, Witt, Olaf, Bougeard, Gaelle, Pajtler, Kristian W, Pfister, Stefan M, Bourdeaut, Franck, Milde, Till
Publicado 2022