Bystander killing of cancer requires the cooperation of CD4(+) and CD8(+) T cells during the effector phase

por Schietinger, Andrea, Philip, Mary, Liu, Rebecca B., Schreiber, Karin, Schreiber, Hans
Publicado 2010

A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs)

por Stone, Jennifer D., Aggen, David H., Schietinger, Andrea, Schreiber, Hans, Kranz, David M.
Publicado 2012

Rejection of immunogenic tumor clones is limited by clonal fraction

por Gejman, Ron S, Chang, Aaron Y, Jones, Heather F, DiKun, Krysta, Hakimi, Abraham Ari, Schietinger, Andrea, Scheinberg, David A
Publicado 2018

52350 PKM2 mediates anti-tumor immunity and T cell dysfunction

por Markowitz, Geoffrey, Ban, Yi, Crowley, Michael, Tavarez, Diamile, Wong, Stephen T.C., Chang, Kenneth, Schietinger, Andrea, Altorki, Nasser, Mittal, Vivek
Publicado 2021

Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors

por Espinosa-Carrasco, Gabriel, Scrivo, Aurora, Zumbo, Paul, Dave, Asim, Betel, Doron, Hellmann, Matthew, Burt, Bryan M, Lee, Hyun-Sung, Schietinger, Andrea
Publicado 2023

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

por Zhang, Bin, Bowerman, Natalie A., Salama, Joseph K., Schmidt, Hank, Spiotto, Michael T., Schietinger, Andrea, Yu, Ping, Fu, Yang-Xin, Weichselbaum, Ralph R., Rowley, Donald A., Kranz, David M., Schreiber, Hans
Publicado 2007

Chromatin states define tumor-specific T cell dysfunction and reprogramming

por Philip, Mary, Fairchild, Lauren, Sun, Liping, Horste, Ellen L., Camara, Steven, Shakiba, Mojdeh, Scott, Andrew C., Viale, Agnes, Lauer, Peter, Merghoub, Taha, Hellmann, Matthew D., Wolchok, Jedd D., Leslie, Christina S., Schietinger, Andrea
Publicado 2017

Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer

por Schietinger, Andrea, Arina, Ainhoa, Liu, Rebecca B, Wells, Sam, Huang, Jianhua, Engels, Boris, Bindokas, Vytas, Bartkowiak, Todd, Lee, David, Herrmann, Andreas, Piston, David W, Pittet, Mikael J, Lin, P Charles, Zal, Tomasz, Schreiber, Hans
Publicado 2013

An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection

por Brennick, Cory A., George, Mariam M., Moussa, Marmar M., Hagymasi, Adam T., Seesi, Sahar Al, Shcheglova, Tatiana V., Englander, Ryan P., Keller, Grant L.J., Balsbaugh, Jeremy L., Baker, Brian M., Schietinger, Andrea, Mandoiu, Ion I., Srivastava, Pramod K.
Publicado 2021

Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging

por Tee, Sui Seng, Kim, Nathaniel, Cullen, Quinlan, Eskandari, Roozbeh, Mamakhanyan, Arsen, Srouji, Rami M., Chirayil, Rachel, Jeong, Sangmoo, Shakiba, Mojdeh, Kastenhuber, Edward R., Chen, Shuibing, Sigel, Carlie, Lowe, Scott W., Jarnagin, William R., Thompson, Craig B., Schietinger, Andrea, Keshari, Kayvan R.
Publicado 2022

GABA Regulates Electrical Activity and Tumor Initiation in Melanoma

por Tagore, Mohita, Hergenreder, Emiliano, Perlee, Sarah C., Cruz, Nelly M., Menocal, Laura, Suresh, Shruthy, Chan, Eric, Baron, Maayan, Melendez, Stephanie, Dave, Asim, Chatila, Walid K., Nsengimana, Jeremie, Koche, Richard P., Hollmann, Travis J., Ideker, Trey, Studer, Lorenz, Schietinger, Andrea, White, Richard M.
Publicado 2023

TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion

por Shakiba, Mojdeh, Zumbo, Paul, Espinosa-Carrasco, Gabriel, Menocal, Laura, Dündar, Friederike, Carson, Sandra E., Bruno, Emmanuel M., Sanchez-Rivera, Francisco J., Lowe, Scott W., Camara, Steven, Koche, Richard P., Reuter, Vincent P., Socci, Nicholas D., Whitlock, Benjamin, Tamzalit, Fella, Huse, Morgan, Hellmann, Matthew D., Wells, Daniel K., Defranoux, Nadine A., Betel, Doron, Philip, Mary, Schietinger, Andrea
Publicado 2021

TOX is a critical regulator of tumour-specific T cell differentiation

por Scott, Andrew C., Dündar, Friederike, Zumbo, Paul, Chandran, Smita S., Klebanoff, Christopher A., Shakiba, Mojdeh, Trivedi, Prerak, Menocal, Laura, Appleby, Heather, Camara, Steven, Zamarin, Dmitriy, Walther, tyler, Snyder, Alexandra, Femia, Matthew R., Comen, Elizabeth A., Wen, Hannah Y., Hellmann, Matthew D., Anandasabapathy, Niroshana, Liu, Yong, Altorki, Nasser K., Lauer, Peter, Levy, Olivier, Glickman, Michael S., Kaye, Jonathan, Betel, Doron, Philip, Mary, Schietinger, Andrea
Publicado 2019

Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma

por Pourmaleki, Maryam, Jones, Caitlin J., Ariyan, Charlotte E., Zeng, Zheng, Pirun, Mono, Navarrete, Daniel A., Li, Yanyun, Zhang, Mianlei, Nandakumar, Subhiksha, Campos, Carl, Nadeem, Saad, Klimstra, David S., Temple-Oberle, Claire F., Brenn, Thomas, Lipson, Evan J., Schenk, Kara M., Stein, Julie E., Taube, Janis M., White, Michael G., Traweek, Raymond, Wargo, Jennifer A., Kirkwood, John M., Gasmi, Billel, Goff, Stephanie L., Corwin, Alex D., McDonough, Elizabeth, Ginty, Fiona, Callahan, Margaret K., Schietinger, Andrea, Socci, Nicholas D., Mellinghoff, Ingo K., Hollmann, Travis J.
Publicado 2022

Ovarian cancer mutational processes drive site-specific immune evasion

por Vázquez-García, Ignacio, Uhlitz, Florian, Ceglia, Nicholas, Lim, Jamie L. P., Wu, Michelle, Mohibullah, Neeman, Niyazov, Juliana, Ruiz, Arvin Eric B., Boehm, Kevin M., Bojilova, Viktoria, Fong, Christopher J., Funnell, Tyler, Grewal, Diljot, Havasov, Eliyahu, Leung, Samantha, Pasha, Arfath, Patel, Druv M., Pourmaleki, Maryam, Rusk, Nicole, Shi, Hongyu, Vanguri, Rami, Williams, Marc J., Zhang, Allen W., Broach, Vance, Chi, Dennis S., Da Cruz Paula, Arnaud, Gardner, Ginger J., Kim, Sarah H., Lennon, Matthew, Long Roche, Kara, Sonoda, Yukio, Zivanovic, Oliver, Kundra, Ritika, Viale, Agnes, Derakhshan, Fatemeh N., Geneslaw, Luke, Issa Bhaloo, Shirin, Maroldi, Ana, Nunez, Rahelly, Pareja, Fresia, Stylianou, Anthe, Vahdatinia, Mahsa, Bykov, Yonina, Grisham, Rachel N., Liu, Ying L., Lakhman, Yulia, Nikolovski, Ines, Kelly, Daniel, Gao, Jianjiong, Schietinger, Andrea, Hollmann, Travis J., Bakhoum, Samuel F., Soslow, Robert A., Ellenson, Lora H., Abu-Rustum, Nadeem R., Aghajanian, Carol, Friedman, Claire F., McPherson, Andrew, Weigelt, Britta, Zamarin, Dmitriy, Shah, Sohrab P.
Publicado 2022

NASH limits anti-tumour surveillance in immunotherapy-treated HCC

por Pfister, Dominik, Núñez, Nicolás Gonzalo, Pinyol, Roser, Govaere, Olivier, Pinter, Matthias, Szydlowska, Marta, Gupta, Revant, Qiu, Mengjie, Deczkowska, Aleksandra, Weiner, Assaf, Müller, Florian, Sinha, Ankit, Friebel, Ekaterina, Engleitner, Thomas, Lenggenhager, Daniela, Moncsek, Anja, Heide, Danijela, Stirm, Kristin, Kosla, Jan, Kotsiliti, Eleni, Leone, Valentina, Dudek, Michael, Yousuf, Suhail, Inverso, Donato, Singh, Indrabahadur, Teijeiro, Ana, Castet, Florian, Montironi, Carla, Haber, Philipp K., Tiniakos, Dina, Bedossa, Pierre, Cockell, Simon, Younes, Ramy, Vacca, Michele, Marra, Fabio, Schattenberg, Jörn M., Allison, Michael, Bugianesi, Elisabetta, Ratziu, Vlad, Pressiani, Tiziana, D’Alessio, Antonio, Personeni, Nicola, Rimassa, Lorenza, Daly, Ann K., Scheiner, Bernhard, Pomej, Katharina, Kirstein, Martha M., Vogel, Arndt, Peck-Radosavljevic, Markus, Hucke, Florian, Finkelmeier, Fabian, Waidmann, Oliver, Trojan, Jörg, Schulze, Kornelius, Wege, Henning, Koch, Sandra, Weinmann, Arndt, Bueter, Marco, Rössler, Fabian, Siebenhüner, Alexander, De Dosso, Sara, Mallm, Jan-Philipp, Umansky, Viktor, Jugold, Manfred, Luedde, Tom, Schietinger, Andrea, Schirmacher, Peter, Emu, Brinda, Augustin, Hellmut G., Billeter, Adrian, Müller-Stich, Beat, Kikuchi, Hiroto, Duda, Dan G., Kütting, Fabian, Waldschmidt, Dirk-Thomas, Ebert, Matthias Philip, Rahbari, Nuh, Mei, Henrik E., Schulz, Axel Ronald, Ringelhan, Marc, Malek, Nisar, Spahn, Stephan, Bitzer, Michael, Ruiz de Galarreta, Marina, Lujambio, Amaia, Dufour, Jean-Francois, Marron, Thomas U., Kaseb, Ahmed, Kudo, Masatoshi, Huang, Yi-Hsiang, Djouder, Nabil, Wolter, Katharina, Zender, Lars, Marche, Parice N., Decaens, Thomas, Pinato, David J., Rad, Roland, Mertens, Joachim C., Weber, Achim, Unger, Kristian, Meissner, Felix, Roth, Susanne, Jilkova, Zuzana Macek, Claassen, Manfred, Anstee, Quentin M., Amit, Ido, Knolle, Percy, Becher, Burkhard, Llovet, Josep M., Heikenwalder, Mathias
Publicado 2021