Development of prophylactic vaccines against HIV-1

por Schiffner, Torben, Sattentau, Quentin J, Dorrell, Lucy
Publicado 2013

Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues

por Maluquer de Motes, Carlos, Schiffner, Torben, Sumner, Rebecca P., Smith, Geoffrey L.
Publicado 2014

The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice

por Wegmann, Frank, Moghaddam, Amin E., Schiffner, Torben, Gartlan, Kate H., Powell, Timothy J., Russell, Rebecca A., Baart, Matthijs, Carrow, Emily W., Sattentau, Quentin J.
Publicado 2015

Humoral responses to HIVconsv induced by heterologous vaccine modalities in rhesus macaques

por Borthwick, Nicola J, Rosario, Maximillian, Schiffner, Torben, Bowles, Emma, Ahmed, Tina, Liljeström, Peter, Stewart-Jones, Guillaume E, Drijfhout, Jan W, Melief, Cornelis J M, Hanke, Tomáš
Publicado 2015

Correction: HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

por Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Publicado 2023

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

por Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Publicado 2017

Comparison of Neutralizing Antibody Responses Elicited from Highly Diverse Polyvalent Heterotrimeric HIV-1 gp140 Cocktail Immunogens versus a Monovalent Counterpart in Rhesus Macaq...

por Bowles, Emma J., Schiffner, Torben, Rosario, Maximillian, Needham, Gemma A., Ramaswamy, Meghna, McGouran, Joanna, Kessler, Benedikt, LaBranche, Celia, McMichael, Andrew J., Montefiori, David, Sattentau, Quentin J., Hanke, Tomáš, Stewart-Jones, Guillaume B. E.
Publicado 2014

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

por Schiffner, Torben, de Val, Natalia, Russell, Rebecca A., de Taeye, Steven W., de la Peña, Alba Torrents, Ozorowski, Gabriel, Kim, Helen J., Nieusma, Travis, Brod, Florian, Cupo, Albert, Sanders, Rogier W., Moore, John P., Ward, Andrew B., Sattentau, Quentin J.
Publicado 2015

Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

por Irimia, Adriana, Serra, Andreia M., Sarkar, Anita, Jacak, Ronald, Kalyuzhniy, Oleksandr, Sok, Devin, Saye-Francisco, Karen L., Schiffner, Torben, Tingle, Ryan, Kubitz, Michael, Adachi, Yumiko, Stanfield, Robyn L., Deller, Marc C., Burton, Dennis R., Schief, William R., Wilson, Ian A.
Publicado 2017

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins

por Schiffner, Torben, Pallesen, Jesper, Russell, Rebecca A., Dodd, Jonathan, de Val, Natalia, LaBranche, Celia C., Montefiori, David, Tomaras, Georgia D., Shen, Xiaoying, Harris, Scarlett L., Moghaddam, Amin E., Kalyuzhniy, Oleksandr, Sanders, Rogier W., McCoy, Laura E., Moore, John P., Ward, Andrew B., Sattentau, Quentin J.
Publicado 2018

Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

por Huang, Deli, Tran, Jenny Tuyet, Olson, Alex, Vollbrecht, Thomas, Tenuta, Mary, Guryleva, Mariia V., Fuller, Roberta P., Schiffner, Torben, Abadejos, Justin R., Couvrette, Lauren, Blane, Tanya R., Saye, Karen, Li, Wenjuan, Landais, Elise, Gonzalez-Martin, Alicia, Schief, William, Murrell, Ben, Burton, Dennis R., Nemazee, David, Voss, James E.
Publicado 2020

Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

por Huang, Deli, Tran, Jenny Tuyet, Olson, Alex, Vollbrecht, Thomas, Tenuta, Mary, Guryleva, Mariia V., Fuller, Roberta P., Schiffner, Torben, Abadejos, Justin R., Couvrette, Lauren, Blane, Tanya R., Saye, Karen, Li, Wenjuan, Landais, Elise, Gonzalez-Martin, Alicia, Schief, William, Murrell, Ben, Burton, Dennis R., Nemazee, David, Voss, James E.
Publicado 2020

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

por Umotoy, Jeffrey, Bagaya, Bernard S., Joyce, Collin, Schiffner, Torben, Menis, Sergey, Saye-Francisco, Karen L., Biddle, Trevor, Mohan, Sanjay, Vollbrecht, Thomas, Kalyuzhniy, Oleksander, Madzorera, Sharon, Kitchin, Dale, Lambson, Bronwen, Nonyane, Molati, Kilembe, William, Poignard, Pascal, Schief, William R., Burton, Dennis R., Murrell, Ben, Moore, Penny L., Briney, Bryan, Sok, Devin, Landais, Elise
Publicado 2019

Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens

por Martin, Gregory M., Russell, Rebecca A., Mundsperger, Philip, Harris, Scarlett, Jovanoska, Lu, Trajano, Luiza Farache, Schiffner, Torben, Fabian, Katalin, Tolazzi, Monica, Scarlatti, Gabriella, McFarlane, Leon, Cheeseman, Hannah, Aldon, Yoann, Schermer, Edith E., Breemen, Marielle, Sliepen, Kwinten, Katinger, Dietmar, Kunert, Renate, Sanders, Rogier W., Shattock, Robin, Ward, Andrew B., Sattentau, Quentin J.
Publicado 2023

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado 2017

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

por Martin, Jacob T., Cottrell, Christopher A., Antanasijevic, Aleksandar, Carnathan, Diane G., Cossette, Benjamin J., Enemuo, Chiamaka A., Gebru, Etse H., Choe, Yury, Viviano, Federico, Fischinger, Stephanie, Tokatlian, Talar, Cirelli, Kimberly M., Ueda, George, Copps, Jeffrey, Schiffner, Torben, Menis, Sergey, Alter, Galit, Schief, William R., Crotty, Shane, King, Neil P., Baker, David, Silvestri, Guido, Ward, Andrew B., Irvine, Darrell J.
Publicado 2020

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

por Rantalainen, Kimmo, Berndsen, Zachary T., Antanasijevic, Aleksandar, Schiffner, Torben, Zhang, Xi, Lee, Wen-Hsin, Torres, Jonathan L., Zhang, Lei, Irimia, Adriana, Copps, Jeffrey, Zhou, Kenneth H., Kwon, Young D., Law, William H., Schramm, Chaim A., Verardi, Raffaello, Krebs, Shelly J., Kwong, Peter D., Doria-Rose, Nicole A., Wilson, Ian A., Zwick, Michael B., Yates, John R., Schief, William R., Ward, Andrew B.
Publicado 2020

B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models

por Huang, Deli, Abbott, Robert K., Havenar-Daughton, Colin, Skog, Patrick D., Al-Kolla, Rita, Groschel, Bettina, Blane, Tanya R., Menis, Sergey, Tran, Jenny Tuyet, Thinnes, Theresa C., Volpi, Sabrina A., Liguori, Alessia, Schiffner, Torben, Villegas, Sophia M., Kalyuzhniy, Oleksandr, Pintea, Mark, Voss, James E., Phelps, Nicole, Tingle, Ryan, Rodriguez, Alberto R., Martin, Greg, Kupryianov, Sergey, deCamp, Allan, Schief, William R., Nemazee, David, Crotty, Shane
Publicado 2020

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

por Steichen, Jon M., Kulp, Daniel W., Tokatlian, Talar, Escolano, Amelia, Dosenovic, Pia, Stanfield, Robyn L., McCoy, Laura E., Ozorowski, Gabriel, Hu, Xiaozhen, Kalyuzhniy, Oleksandr, Briney, Bryan, Schiffner, Torben, Garces, Fernando, Freund, Natalia T., Gitlin, Alexander D., Menis, Sergey, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Jones, Meaghan, Mutafyan, Andrew A., Yun, Dong Soo, Mayer, Christian T., Ward, Andrew B., Burton, Dennis R., Wilson, Ian A., Irvine, Darrell J., Nussenzweig, Michel C., Schief, William R.
Publicado 2016

Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

por Willis, Jordan R., Berndsen, Zachary T., Ma, Krystal M., Steichen, Jon M., Schiffner, Torben, Landais, Elise, Liguori, Alessia, Kalyuzhniy, Oleksandr, Allen, Joel D., Baboo, Sabyasachi, Omorodion, Oluwarotimi, Diedrich, Jolene K., Hu, Xiaozhen, Georgeson, Erik, Phelps, Nicole, Eskandarzadeh, Saman, Groschel, Bettina, Kubitz, Michael, Adachi, Yumiko, Mullin, Tina-Marie, Alavi, Nushin B., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Wilson, Ian A., Yates, John R., Paulson, James C., Crispin, Max, Ward, Andrew B., Schief, William R.
Publicado 2022