Novel Bruton’s Tyrosine Kinase inhibitor remibrutinib: Drug‐drug interaction potential as a victim of CYP3A4 inhibitors based on clinical data and PBPK modeling

por Huth, Felix, Schiller, Hilmar, Jin, Yi, Poller, Birk, Schuhler, Carole, Weis, Wendy, Woessner, Ralph, Drollmann, Anton, End, Peter
Publicado 2021

An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

por James, Alexander D., Schiller, Hilmar, Marvalin, Cyrille, Jin, Yi, Borell, Hubert, Roffel, Ad F., Glaenzel, Ulrike, Ji, Yan, Camenisch, Gian
Publicado 2020

The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease

por Neumann, Ulf, Ufer, Mike, Jacobson, Laura H, Rouzade‐Dominguez, Marie‐Laure, Huledal, Gunilla, Kolly, Carine, Lüönd, Rainer M, Machauer, Rainer, Veenstra, Siem J, Hurth, Konstanze, Rueeger, Heinrich, Tintelnot‐Blomley, Marina, Staufenbiel, Matthias, Shimshek, Derya R, Perrot, Ludovic, Frieauff, Wilfried, Dubost, Valerie, Schiller, Hilmar, Vogg, Barbara, Beltz, Karen, Avrameas, Alexandre, Kretz, Sandrine, Pezous, Nicole, Rondeau, Jean‐Michel, Beckmann, Nicolau, Hartmann, Andreas, Vormfelde, Stefan, David, Olivier J, Galli, Bruno, Ramos, Rita, Graf, Ana, Lopez Lopez, Cristina
Publicado 2018