Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2)

por Valdivia, Andres, Vagadia, Purav P., Guo, Guangxu, O’Brien, Eilidh, Matei, Daniela, Schiltz, Gary E.
Publicado 2023

Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists

por Mishra, Rama K., Shum, Andrew K., Platanias, Leonidas C., Miller, Richard J., Schiltz, Gary E.
Publicado 2016

Going beyond Polycomb: EZH2 Functions in Prostate Cancer

por Park, Su H., Fong, Ka-Wing, Mong, Ezinne, Martin, M. Cynthia, Schiltz, Gary E., Yu, Jindan
Publicado 2021

SSWAP: A Simple Semantic Web Architecture and Protocol for semantic web services

por Gessler, Damian DG, Schiltz, Gary S, May, Greg D, Avraham, Shulamit, Town, Christopher D, Grant, David, Nelson, Rex T
Publicado 2009

Regulation of IFNα-induced expression of the short ACE2 isoform by ULK1

por Perez, Ricardo E., Saleiro, Diana, Ilut, Liliana, Schiltz, Gary E., Eckerdt, Frank, Fish, Eleanor N., Platanias, Leonidas C.
Publicado 2022

Positive Allosteric Modulator of SERCA Pump NDC-1173 Exerts Beneficial Effects in Mouse Model of Alzheimer’s Disease

por Dahl, Russell, Moore, Amanda C., Knight, Caitlynn, Mauger, Colleen, Zhang, Hua, Schiltz, Gary E., Koss, Wendy A., Bezprozvanny, Ilya
Publicado 2023

Identification of a druggable protein–protein interaction site between mutant p53 and its stabilizing chaperone DNAJA1

por Tong, Xin, Xu, Dandan, Mishra, Rama K., Jones, Ryan D., Sun, Leyu, Schiltz, Gary E., Liao, Jie, Yang, Guang-Yu
Publicado 2020

Effects of Small Molecule Ligands on ACKR3 Receptors

por Hopkins, Brittany E., Masuho, Ikuo, Ren, Dongjun, Iyamu, Iredia D., Lv, Wei, Malik, Neha, Martemyanov, Kirill A., Schiltz, Gary E., Miller, Richard J.
Publicado 2022

A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression

por Holmes, Austin G., Parker, J. Brandon, Sagar, Vinay, Truica, Mihai I., Soni, Pritin N., Han, Huiying, Schiltz, Gary E., Abdulkadir, Sarki A., Chakravarti, Debabrata
Publicado 2022

A novel strategy to block mitotic progression for targeted therapy

por Chi, Junlong (Jack), Li, Hongchun, Zhou, Zhuan, Izquierdo-Ferrer, Javier, Xue, Yifan, Wavelet, Cindy M., Schiltz, Gary E., Zhang, Bin, Cristofanilli, Massimo, Lu, Xinghua, Bahar, Ivet, Wan, Yong
Publicado 2019

Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons

por Han, Ye, Iyamu, Iredia D., Clutter, Matthew R., Mishra, Rama K., Lyman, Kyle A., Zhou, Chengwen, Michailidis, Ioannis, Xia, Maya Y., Sharma, Horrick, Luan, Chi-Hao, Schiltz, Gary E., Chetkovich, Dane M.
Publicado 2022

Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth

por Gritsina, Galina, Fong, Ka-wing, Lu, Xiaodong, Lin, Zhuoyuan, Xie, Wanqing, Agarwal, Shivani, Lin, Dong, Schiltz, Gary E., Beltran, Himisha, Corey, Eva, Morrissey, Colm, Wang, Yuzhuo, Zhao, Jonathan C., Hussain, Maha, Yu, Jindan
Publicado 2023

Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds

por Caesar, Lindsay K., Robey, Matthew T., Swyers, Michael, Islam, Md N., Ye, Rosa, Vagadia, Purav P., Schiltz, Gary E., Thomas, Paul M., Wu, Chengcang C., Kelleher, Neil L., Keller, Nancy P., Bok, Jin Woo
Publicado 2020

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia

por Zhao, Zibo, Wang, Lu, Volk, Andrew G., Birch, Noah W., Stoltz, Kristen L., Bartom, Elizabeth T., Marshall, Stacy A., Rendleman, Emily J., Nestler, Carson M., Shilati, Joseph, Schiltz, Gary E., Crispino, John D., Shilatifard, Ali
Publicado 2019

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

por Zhai, Lijie, Bell, April, Ladomersky, Erik, Lauing, Kristen L., Bollu, Lakshmi, Sosman, Jeffrey A., Zhang, Bin, Wu, Jennifer D., Miller, Stephen D., Meeks, Joshua J., Lukas, Rimas V., Wyatt, Eugene, Doglio, Lynn, Schiltz, Gary E., McCusker, Robert H., Wainwright, Derek A.
Publicado 2020

Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models

por Han, Xu, Mei, Yang, Mishra, Rama K., Bi, Honghao, Jain, Atul D., Schiltz, Gary E., Zhao, Baobing, Sukhanova, Madina, Wang, Pan, Grigorescu, Arabela A., Weber, Patricia C., Piwinski, John J., Prado, Miguel A., Paulo, Joao A., Stephens, Len, Anderson, Karen E., Abrams, Charles S., Yang, Jing, Ji, Peng
Publicado 2023

Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma

por Zhai, Lijie, Bell, April, Ladomersky, Erik, Lauing, Kristen L., Bollu, Lakshmi, Nguyen, Brenda, Genet, Matthew, Kim, Miri, Chen, Peiwen, Mi, Xinlei, Wu, Jennifer D., Schipma, Matthew J., Wray, Brian, Griffiths, John, Unwin, Richard D., Clark, Simon J., Acharya, Rajesh, Bao, Riyue, Horbinski, Craig, Lukas, Rimas V., Schiltz, Gary E., Wainwright, Derek A.
Publicado 2021

Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma

por Bollu, Lakshmi R., Bommi, Prashant V., Monsen, Paige J., Zhai, Lijie, Lauing, Kristen L., Bell, April, Kim, Miri, Ladomersky, Erik, Yang, Xinyu, Platanias, Leonidas C., Matei, Daniela E., Bonini, Marcelo G., Munshi, Hidayatullah G., Hashizume, Rintaro, Wu, Jennifer D., Zhang, Bin, James, Charles David, Chen, Peiwen, Kocherginsky, Masha, Horbinski, Craig, Cameron, Michael D., Grigorescu, Arabela A., Yamini, Bakhtiar, Lukas, Rimas V., Schiltz, Gary E., Wainwright, Derek A.
Publicado 2022

Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence

por Johnson, Margaret, Bell, April, Lauing, Kristen L., Ladomersky, Erik, Zhai, Lijie, Penco-Campillo, Manon, Shah, Yajas, Mauer, Elizabeth, Xiu, Joanne, Nicolaides, Theodore, Drumm, Michael, McCortney, Kathleen, Elemento, Olivier, Kim, Miri, Bommi, Prashant, Low, Justin T., Memon, Ruba, Wu, Jennifer, Zhao, Junfei, Mi, Xinlei, Glantz, Michael J., Sengupta, Soma, Castro, Brandyn, Yamini, Bakhtiar, Horbinski, Craig, Baker, Darren J., Walunas, Theresa L., Schiltz, Gary E., Lukas, Rimas V., Wainwright, Derek A.
Publicado 2023

The Generation Challenge Programme Platform: Semantic Standards and Workbench for Crop Science

por Bruskiewich, Richard, Senger, Martin, Davenport, Guy, Ruiz, Manuel, Rouard, Mathieu, Hazekamp, Tom, Takeya, Masaru, Doi, Koji, Satoh, Kouji, Costa, Marcos, Simon, Reinhard, Balaji, Jayashree, Akintunde, Akinnola, Mauleon, Ramil, Wanchana, Samart, Shah, Trushar, Anacleto, Mylah, Portugal, Arllet, Ulat, Victor Jun, Thongjuea, Supat, Braak, Kyle, Ritter, Sebastian, Dereeper, Alexis, Skofic, Milko, Rojas, Edwin, Martins, Natalia, Pappas, Georgios, Alamban, Ryan, Almodiel, Roque, Barboza, Lord Hendrix, Detras, Jeffrey, Manansala, Kevin, Mendoza, Michael Jonathan, Morales, Jeffrey, Peralta, Barry, Valerio, Rowena, Zhang, Yi, Gregorio, Sergio, Hermocilla, Joseph, Echavez, Michael, Yap, Jan Michael, Farmer, Andrew, Schiltz, Gary, Lee, Jennifer, Casstevens, Terry, Jaiswal, Pankaj, Meintjes, Ayton, Wilkinson, Mark, Good, Benjamin, Wagner, James, Morris, Jane, Marshall, David, Collins, Anthony, Kikuchi, Shoshi, Metz, Thomas, McLaren, Graham, van Hintum, Theo
Publicado 2008