Neurotoxicity of Engineered Nanomaterials: Testing Considerations

por Scarcello, Eleonora, Sofranko, Adriana, Wahle, Tina, Schins, Roel P. F.
Publicado 2022

Evaluation of the NLRP3 Inflammasome Activating Effects of a Large Panel of TiO(2) Nanomaterials in Macrophages

por Kolling, Julia, Tigges, Jonas, Hellack, Bryan, Albrecht, Catrin, Schins, Roel P. F.
Publicado 2020

Investigating the Role of the NLRP3 Inflammasome Pathway in Acute Intestinal Inflammation: Use of THP-1 Knockout Cell Lines in an Advanced Triple Culture Model

por Busch, Mathias, Ramachandran, Haribaskar, Wahle, Tina, Rossi, Andrea, Schins, Roel P. F.
Publicado 2022

Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model

por Bredeck, Gerrit, Dobner, Jochen, Stahlmecke, Burkhard, Fomba, Khanneh Wadinga, Herrmann, Hartmut, Rossi, Andrea, Schins, Roel P. F.
Publicado 2023

Ingested Engineered Nanomaterials Affect the Expression of Mucin Genes—An In Vitro-In Vivo Comparison

por Bredeck, Gerrit, Kämpfer, Angela A. M., Sofranko, Adriana, Wahle, Tina, Büttner, Veronika, Albrecht, Catrin, Schins, Roel P. F.
Publicado 2021

Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models

por Busch, Mathias, Brouwer, Hugo, Aalderink, Germaine, Bredeck, Gerrit, Kämpfer, Angela A. M., Schins, Roel P. F., Bouwmeester, Hans
Publicado 2023

Mechanistic Insights into the Role of Iron, Copper, and Carbonaceous Component on the Oxidative Potential of Ultrafine Particulate Matter

por Tacu, Ion, Kokalari, Ida, Abollino, Ornella, Albrecht, Catrin, Malandrino, Mery, Ferretti, Anna Maria, Schins, Roel P. F., Fenoglio, Ivana
Publicado 2021

Effects of subchronic dietary exposure to the engineered nanomaterials SiO(2) and CeO(2) in C57BL/6J and 5xFAD Alzheimer model mice

por Sofranko, Adriana, Wahle, Tina, Kolling, Julia, Heusinkveld, Harm J., Stahlmecke, Burkhard, Rosenbruch, Martin, Albrecht, Catrin, Schins, Roel P. F.
Publicado 2022

Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascul...

por Wahle, Tina, Sofranko, Adriana, Dekkers, Susan, Miller, Mark R., Heusinkveld, Harm J., Albrecht, Catrin, Cassee, Flemming R., Schins, Roel P.F.
Publicado 2020

Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells

por Busch, Mathias, Bredeck, Gerrit, Waag, Friedrich, Rahimi, Khosrow, Ramachandran, Haribaskar, Bessel, Tobias, Barcikowski, Stephan, Herrmann, Andreas, Rossi, Andrea, Schins, Roel P. F.
Publicado 2022

Respiratory Effects of Fine and Ultrafine Particles from Indoor Sources—A Randomized Sham-Controlled Exposure Study of Healthy Volunteers

por Soppa, Vanessa J., Schins, Roel P. F., Hennig, Frauke, Hellack, Bryan, Quass, Ulrich, Kaminski, Heinz, Kuhlbusch, Thomas A. J., Hoffmann, Barbara, Weinmayr, Gudrun
Publicado 2014

Correction: Soppa, V.J., et al. Respiratory Effects of Fine and Ultrafine Particles from Indoor Sources—A Randomized Sham-Controlled Exposure Study of Healthy Volunteers Int. J. En...

por Soppa, Vanessa J., Schins, Roel P. F., Hennig, Frauke, Hellack, Bryan, Quass, Ulrich, Kaminski, Heinz, Kuhlbusch, Thomas A. J., Hoffmann, Barbara, Weinmayr, Gudrun
Publicado 2014

Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways

por Stermann, Torben, Nguyen, Thach, Stahlmecke, Burkhard, Todea, Ana Maria, Woeste, Selina, Hacheney, Inken, Krutmann, Jean, Unfried, Klaus, Schins, Roel P. F., Rossi, Andrea
Publicado 2022

Zinc Oxide Nanoparticles Induce Necrosis and Apoptosis in Macrophages in a p47phox- and Nrf2-Independent Manner

por Wilhelmi, Verena, Fischer, Ute, Weighardt, Heike, Schulze-Osthoff, Klaus, Nickel, Carmen, Stahlmecke, Burkhard, Kuhlbusch, Thomas A. J., Scherbart, Agnes M., Esser, Charlotte, Schins, Roel P. F., Albrecht, Catrin
Publicado 2013

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

por Peeters, Paul M, Eurlings, Irene M J, Perkins, Timothy N, Wouters, Emiel F, Schins, Roel P F, Borm, Paul J A, Drommer, Wolfgang, Reynaert, Niki L, Albrecht, Catrin
Publicado 2014

Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer’s disease

por Hullmann, Maja, Albrecht, Catrin, van Berlo, Damiën, Gerlofs-Nijland, Miriam E., Wahle, Tina, Boots, Agnes W., Krutmann, Jean, Cassee, Flemming R., Bayer, Thomas A., Schins, Roel P. F.
Publicado 2017

Digital research data: from analysis of existing standards to a scientific foundation for a modular metadata schema in nanosafety

por Elberskirch, Linda, Binder, Kunigunde, Riefler, Norbert, Sofranko, Adriana, Liebing, Julia, Minella, Christian Bonatto, Mädler, Lutz, Razum, Matthias, van Thriel, Christoph, Unfried, Klaus, Schins, Roel P. F., Kraegeloh, Annette
Publicado 2022

How Structured Metadata Acquisition Contributes to the Reproducibility of Nanosafety Studies: Evaluation by a Round-Robin Test

por Elberskirch, Linda, Sofranko, Adriana, Liebing, Julia, Riefler, Norbert, Binder, Kunigunde, Bonatto Minella, Christian, Razum, Matthias, Mädler, Lutz, Unfried, Klaus, Schins, Roel P. F., Kraegeloh, Annette, van Thriel, Christoph
Publicado 2022

The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice

por Boots, Agnes W., Veith, Carmen, Albrecht, Catrin, Bartholome, Roger, Drittij, Marie-José, Claessen, Sandra M. H., Bast, Aalt, Rosenbruch, Martin, Jonkers, Leonie, van Schooten, Frederik-Jan, Schins, Roel P. F.
Publicado 2020

Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species

por Schiavi, Alfonso, Cirotti, Claudia, Gerber, Lora-Sophie, Di Lauro, Giulia, Maglioni, Silvia, Shibao, Priscila Yumi Tanaka, Montresor, Sabrina, Kirstein, Janine, Petzsch, Patrick, Köhrer, Karl, Schins, Roel P. F., Wahle, Tina, Barilà, Daniela, Ventura, Natascia
Publicado 2023