The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation

por Shen, Zhong-Jian, Esnault, Stephane, Schinzel, Anna, Borner, Christoph, Malter, James S
Publicado 2009

Conformational control of Bax localization and apoptotic activity by Pro168

por Schinzel, Anna, Kaufmann, Thomas, Schuler, Martin, Martinalbo, Jorge, Grubb, David, Borner, Christoph
Publicado 2004

Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

por Hettmer, Simone, Schinzel, Anna C, Tchessalova, Daria, Richards, Nigel, Hahn, William C, Wagers, Amy J
Publicado 2015

Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

por Hettmer, Simone, Schinzel, Anna C, Tchessalova, Daria, Schneider, Michaela, Parker, Christina L, Bronson, Roderick T, Richards, Nigel GJ, Hahn, William C, Wagers, Amy J
Publicado 2015

PRKACA Mediates Resistance to HER2-Targeted Therapy in Breast Cancer Cells and Restores Anti-Apoptotic Signaling

por Moody, Susan E., Schinzel, Anna C., Singh, Shambhavi, Izzo, Francesca, Strickland, Matthew R., Luo, Leo, Thomas, Sapana R., Boehm, Jesse S., Kim, So Young, Wang, Zhigang C., Hahn, William C.
Publicado 2014

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

por Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Publicado 2010

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

por Day, Tovah A., Layer, Jacob V., Cleary, J. Patrick, Guha, Srijoy, Stevenson, Kristen E., Tivey, Trevor, Kim, Sunhee, Schinzel, Anna C., Izzo, Francesca, Doench, John, Root, David E., Hahn, William C., Price, Brendan D., Weinstock, David M.
Publicado 2017

Corrigendum: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

por Day, Tovah A., Layer, Jacob V., Cleary, J. Patrick, Guha, Srijoy, Stevenson, Kristen E., Tivey, Trevor, Kim, Sunhee, Schinzel, Anna C, Izzo, Francesca, Doench, John, Root, David E., Hahn, William C., Price, Brendan D., Weinstock, David M.
Publicado 2017

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

por Oser, Matthew G., Sabet, Amin H., Gao, Wenhua, Chakraborty, Abhishek A., Schinzel, Anna C., Jennings, Rebecca B., Fonseca, Raquel, Bonal, Dennis M., Booker, Matthew A., Flaifel, Abdallah, Novak, Jesse S., Christensen, Camilla L., Zhang, Hua, Herbert, Zachary T., Tolstorukov, Michael Y., Buss, Elizabeth J., Wong, Kwok-Kin, Bronson, Roderick T., Nguyen, Quang-De, Signoretti, Sabina, Kaelin, William G.
Publicado 2019

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation

por Lane, Andrew A., Chapuy, Bjoern, Lin, Charles Y., Tivey, Trevor, Li, Hubo, Townsend, Elizabeth C., van Bodegom, Diederik, Day, Tovah A., Wu, Shuo-Chieh, Liu, Huiyun, Yoda, Akinori, Alexe, Gabriela, Schinzel, Anna C., Sullivan, Timothy J., Malinge, Sébastien, Taylor, Jordan E., Stegmaier, Kimberly, Jaffe, Jacob D., Bustin, Michael, te Kronnie, Geertruy, Izraeli, Shai, Harris, Marian, Stevenson, Kristen E., Neuberg, Donna, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Hahn, William C., Crispino, John D., Pellman, David, Weinstock, David M.
Publicado 2014

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

por Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Sandy, Peter, Meylan, Etienne, Scholl, Claudia, Fröhling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig, Silver, Serena J., Weir, Barbara A., Reiling, Jan H., Sheng, Qing, Gupta, Piyush B., Wadlow, Raymond C., Le, Hanh, Hoersch, Sebastian, Wittner, Ben S., Ramaswamy, Sridhar, Livingston, David M., Sabatini, David M., Meyerson, Matthew, Thomas, Roman K., Lander, Eric S., Mesirov, Jill P., Root, David E., Gilliland, D. Gary, Jacks, Tyler, Hahn, William C.
Publicado 2009

Initial genome sequencing and analysis of multiple myeloma

por Chapman, Michael A., Lawrence, Michael S., Keats, Jonathan J., Cibulskis, Kristian, Sougnez, Carrie, Schinzel, Anna C., Harview, Christina L., Brunet, Jean-Philippe, Ahmann, Gregory J., Adli, Mazhar, Anderson, Kenneth C., Ardlie, Kristin G., Auclair, Daniel, Baker, Angela, Bergsagel, P. Leif, Bernstein, Bradley E., Drier, Yotam, Fonseca, Rafael, Gabriel, Stacey B., Hofmeister, Craig C., Jagannath, Sundar, Jakubowiak, Andrzej J., Krishnan, Amrita, Levy, Joan, Liefeld, Ted, Lonial, Sagar, Mahan, Scott, Mfuko, Bunmi, Monti, Stefano, Perkins, Louise M., Onofrio, Robb, Pugh, Trevor J., Vincent Rajkumar, S., Ramos, Alex H., Siegel, David S., Sivachenko, Andrey, Trudel, Suzanne, Vij, Ravi, Voet, Douglas, Winckler, Wendy, Zimmerman, Todd, Carpten, John, Trent, Jeff, Hahn, William C., Garraway, Levi A., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R.
Publicado 2011