Characterization of drug-induced human mitochondrial ADP/ATP carrier inhibition

por Jaiquel Baron, Stephany, King, Martin S., Kunji, Edmund R.S., Schirris, Tom J.J.
Publicado 2021

Statins and Cardiomyocyte Metabolism, Friend or Foe?

por Somers, Tim, Siddiqi, Sailay, Morshuis, Wim J., Russel, Frans G. M., Schirris, Tom J. J.
Publicado 2023

Dissecting Drug-Induced Cytotoxicity and Metabolic Dysfunction in Conditionally Immortalized Human Proximal Tubule Cells

por Hoogstraten, Charlotte A., Smeitink, Jan A. M., Russel, Frans G. M., Schirris, Tom J. J.
Publicado 2022

Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity

por Schirris, Tom J. J., Ritschel, Tina, Herma Renkema, G., Willems, Peter H. G. M., Smeitink, Jan A. M., Russel, Frans G. M.
Publicado 2015

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

por Tavoulari, Sotiria, Schirris, Tom J.J., Mavridou, Vasiliki, Thangaratnarajah, Chancievan, King, Martin S., Jones, Daniel T.D., Ding, Shujing, Fearnley, Ian M., Kunji, Edmund R.S.
Publicado 2022

Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis

por Somers, Tim, Allard, Neeltje A. E., Siddiqi, Sailay, Janssen, Margit C. M., Hopman, Maria T. E., Morshuis, Wim J., Russel, Frans G. M., Timmers, Silvie, Schirris, Tom J. J.
Publicado 2023

Metabolic impact of genetic and chemical ADP/ATP carrier inhibition in renal proximal tubule epithelial cells

por Hoogstraten, Charlotte A., Jacobs, Maaike M. E., de Boer, Guido, van de Wal, Melissa A. E., Koopman, Werner J. H., Smeitink, Jan A. M., Russel, Frans G. M., Schirris, Tom J. J.
Publicado 2023

Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention

por van de Wal, Melissa A E, Adjobo-Hermans, Merel J W, Keijer, Jaap, Schirris, Tom J J, Homberg, Judith R, Wieckowski, Mariusz R, Grefte, Sander, van Schothorst, Evert M, van Karnebeek, Clara, Quintana, Albert, Koopman, Werner J H
Publicado 2021

Safety of drug use in patients with a primary mitochondrial disease: An international Delphi‐based consensus

por De Vries, Maaike C., Brown, David A., Allen, Mitchell E., Bindoff, Laurence, Gorman, Gráinne S., Karaa, Amel, Keshavan, Nandaki, Lamperti, Costanza, McFarland, Robert, Ng, Yi Shiau, O'Callaghan, Mar, Pitceathly, Robert D. S., Rahman, Shamima, Russel, Frans G. M., Varhaug, Kristin N., Schirris, Tom J. J., Mancuso, Michelangelo
Publicado 2020